A novel finite element (FE) based technique is introduced, which can be applied for real-time or near real-time soft
tissue deformation calculation, irrespective of the complexities arising from the tissue constitutive law or loading
conditions. Unlike classical FE methods, which are computationally slow, this technique is very fast and yet highly
accurate. The proposed technique is based on statistical analysis of pre-processed FE models on a class of organ shapes
similar to the object shape of interest. We show that FE analysis results of any new shape in the class of objects can be
obtained by a linear combination of main modes of the FE output parameter space. Several examples are presented for
validation and finally an application of this method in real-time elastography is demonstrated.