Influence of low power laser irradiance on healthy skin using diffuse reflectance spectroscopy and multispectral
imaging was studied. Changes of diffuse reflectance spectra in spectral range from 500 to 600 nm were observed after
405 nm, 473 nm and 532 nm laser provocation, leading to conclusion that the content of skin hemoglobin has changed.
Peaks in spectral absorbance (optical density) curves corresponded to well-known oxy-hemoglobin absorbance peaks at
542 and 577 nm.
The autofluorescence photobleaching intensity dynamics of in vivo skin and skin pathologies under continuous 532 nm
laser irradiation have been studied. Overall the 141 human skin malformations were investigated by laser induced skin
autofluorescence photobleaching analysis. Details of equipment are described along with some measurement results
illustrating potentiality of the technology.
Photo-bleaching of in-vivo skin autofluorescence intensity under continuous low power laser irradiation has been
studied. Temporal behavior of single-spot fluorescence and spectral fluorescent images have been studied at continuous
405 nm, 473 nm and 532 nm laser excitation and/or pre-irradiation, with power densities well below the laser-skin safety
limits. Skin autofluorescence photo-memory effects (laser signatures) have been observed and analyzed, as well.