The making of new nanomaterials for deep tissue imaging is important for clinic applications. In this work, Erbium based metal organic complex nanoparticles is synthesized. They show near-infrared fluorescence (800-1100 nm) when excited by 785 nm light. Deep tissues imaging is demonstrated using a nanoparticle-loaded 2 mL centrifuge tube covered with pig bacon meat tissue. The maximum imaging depth larger than 1.4 cm is achieved. Our work provides a validated procedure to make nanoparticles for near infrared deep tissue imaging.