In recent years, optical detection technology for human skin has developed rapidly. This paper introduces a novel imaging technique, polarization parameters indirect microscopic imaging. We insert polarization-modulation mechanics into a conventional reflection microscopic imaging system. Instead of normal light source, we use a high transmission infrared light source. The resolution of such optical microscopy can reach to 100 nanometers. Using this imaging system, we can obtain multiple optical vector parameters such as polarization phase, degree of polarizations ,wave vector phrase, spatial angles, angles and modulation etc. By analyzing the polarization parameters, we obtain inversion images of human skin.