PROCEEDINGS ARTICLE | December 11, 2012
Proc. SPIE. 8553, Optics in Health Care and Biomedical Optics V
KEYWORDS: Medicine, Biomedical optics, Nanoparticles, Silver, Surface enhanced Raman spectroscopy, Raman spectroscopy, Cardiovascular system, Solids, Solid state physics, Signal detection
Due to its high sensitivity, flexibility, and “fingerprints” sensing capability, Surface-enhanced Raman Spectroscopy
(SERS) is a very powerful method for characterization of substances. In this paper, two kinds of Radix Astragali with
different quality were firstly extracted through continuous circumfluence extraction method and then mixed with silver
nanoparticles for SERS detection. Most Raman bands obtained in Radix Astragali extraction solution are found at
300-7000cm-1 and 900-1390 cm-1. Although, major peak positions at 470, 556, 949, 1178 and 1286 cm-1 found in these
two kinds of Radix Astragali appear nearly the same, Raman bands of 556 and 1178 cm-1 are different in intensity, thus
may be used as a characteristic marker of Radix Astragali quality. In detail, we can make full use of the different
intensity of two different kinds but the same state at 556 cm-1 to describe the quality standard of Radix Astragali. Our
preliminary results show that SERS combining with continuous circumfluence extraction method may provide a direct,
accurate and rapid detection method of Radix Astragali.
