Prof. Jürgen Lademann Profile

Prof. Jürgen Lademann

Professor at Charite Universitaetsmedizin Berlin

SPIE Involvement:

Conference Program Committee | Author

Publications (87)

Proceedings Article | 3 March 2020 Paper

A diode laser based clinical diagnostic system using shifted excitation resonance Raman difference spectroscopy for the in vivo detection of ß-carotene in human skin

Bernd Sumpf, Marcel Braune, Martin Maiwald, Maxim Darvin, Jürgen Lademann, Günther Tränkle

Proceedings Volume 11257, 1125707 (2020) https://doi.org/10.1117/12.2554015

KEYWORDS: Raman spectroscopy, Skin, Semiconductor lasers, Light sources, Diagnostics, Spectroscopy, In vivo imaging, Laser development, Raman scattering, Absorption

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Proceedings Article | 21 February 2020 Paper

Confocal Raman microspectroscopy for evaluation of optical clearing efficiency of the skin ex vivo

I. Yu. Yanina, J. Schleusener, J. Lademann, V. Tuchin, M. Darvin

Proceedings Volume 11239, 112390W (2020) https://doi.org/10.1117/12.2550352

KEYWORDS: Skin, Raman spectroscopy, Confocal microscopy, Optical clearing, Imaging spectroscopy, Tissues, Water, Tissue optics, Scattering, Ear

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Proceedings Article | 4 March 2019 Presentation

SPF determination of sunscreens with UV-LED (Conference Presentation)

Jürgen Lademann

Proceedings Volume 10877, 108770Q (2019) https://doi.org/10.1117/12.2509704

KEYWORDS: Skin, Ultraviolet radiation, Sun, Optical fibers, Tissue optics, Sensors, Light emitting diodes, In vivo imaging

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Proceedings Article | 15 March 2018 Presentation

Application of spectroscopic methods for the prevention of side effects on patients during chemotherapy (Conference Presentation)

Jürgen Lademann, Maxim Darvin, Johannes Schleusener, Gisela Thiede, Thomas Bocklitz, Martina Meinke, Sora Jung

Proceedings Volume 10493, 104930M (2018) https://doi.org/10.1117/12.2316588

KEYWORDS: Skin, Spectroscopy, Luminescence, Cancer, Oncology, Raman spectroscopy

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SPIE Journal Paper | 28 July 2017 Open Access

In vivo characterization of structural changes after topical application of glucocorticoids in healthy human skin

Sora Jung, Jürgen Lademann, Maxim Darvin, Claudia Richter, Claus Pedersen, Heike Richter, Sabine Schanzer, Jan Kottner, Ulrike Blume-Peytavi, Mads Røpke

JBO, Vol. 22, Issue 07, 076018, (July 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.7.076018

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SPIE Journal Paper | 5 January 2017 Open Access

Depth-dependent autofluorescence photobleaching using 325, 473, 633, and 785 nm of porcine ear skin ex vivo

Johannes Schleusener, Jürgen Lademann, Maxim Darvin

JBO, Vol. 22, Issue 09, 091503, (January 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.9.091503

KEYWORDS: Skin, Luminescence, Raman spectroscopy, In vivo imaging, Ultraviolet radiation, Ear, Confocal microscopy, Collagen, Microscopes, Near infrared

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SPIE Journal Paper | 20 October 2016 Open Access

Comparison of different cutaneous carotenoid sensors and influence of age, skin type, and kinetic changes subsequent to intake of a vegetable extract

Martina Meinke, Sabine Schanzer, Silke Lohan, Ihar Shchatsinin, Maxim Darvin, Henning Vollert, Björn Magnussen, Wolfang Köcher, Jürgen Helfmann, Jürgen Lademann

JBO, Vol. 21, Issue 10, 107002, (October 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.10.107002

KEYWORDS: Skin, Sensors, Blood, Calibration, Reflectance spectroscopy, Raman spectroscopy, Remote sensing, Scanning electron microscopy, Reflectivity, Plasma

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SPIE Journal Paper | 27 May 2016 Open Access

In vivo/ex vivo targeting of Langerhans cells after topical application of the immune response modifier TMX-202: confocal Raman microscopy and histology analysis

Maxim Darvin, Gisela Thiede, Saul Mujica Ascencio, Sabine Schanzer, Heike Richter, Sabrina Vinzón, Daniel Hasche, Frank Rösl, Roberto May, Yohan Hazot, Dov Tamarkin, Juergen Lademann

JBO, Vol. 21, Issue 05, 055004, (May 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.5.055004

KEYWORDS: Skin, Raman spectroscopy, Confocal microscopy, Microscopy, Ear, In vivo imaging, Principal component analysis, Foam, Biological research, Laser scanners

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Proceedings Article | 26 April 2016 Presentation

Topical application of nanoparticles: prospects and safety aspects (Conference Presentation)

Jürgen Lademann, Heike Richter, Sora Jung, Martina Meinke, Eckart Rühl, Ulrike Alexiev, Marcelo Calderon, Alexa Patzelt

Proceedings Volume 9707, 97070I (2016) https://doi.org/10.1117/12.2212109

KEYWORDS: Nanoparticles, Particles, Skin, Safety, Blood vessels, Biomedical optics, Photonics, Current controlled current source

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SPIE Journal Paper | 26 April 2016 Open Access

Detection of capecitabine (Xeloda^®) on the skin surface after oral administration

Mao-Dong Huang, Harald Fuss, Jürgen Lademann, Stefan Florek, Alexa Patzelt, Martina Meinke, Sora Jung

JBO, Vol. 21, Issue 04, 047002, (April 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.4.047002

KEYWORDS: Skin, Fluorine, Personal protective equipment, Statistical analysis, Absorption, Spectroscopy, Magnesium, Cancer, Colorectal cancer, Oncology

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Proceedings Article | 12 March 2015 Paper

Penetration of spherical and rod-like gold nanoparticles into intact and barrier-disrupted human skin

Christina Graf, Daniel Nordmeyer, Sebastian Ahlberg, Jörg Raabe, Annika Vogt, Jürgen Lademann, Fiorenza Rancan, Eckart Rühl

Proceedings Volume 9338, 93381L (2015) https://doi.org/10.1117/12.2079719

KEYWORDS: Skin, Gold, Nanoparticles, Scanning electron microscopy, X-ray microscopy, Particles, Spherical lenses, X-rays, Transmission electron microscopy, Nanorods

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SPIE Journal Paper | 2 December 2014 Open Access

Characterization of atopic skin and the effect of a hyperforin-rich cream by laser scanning microscopy

Martina Meinke, Heike Richter, Anke Kleemann, Juergen Lademann, Kathrin Tscherch, Sascha Rohn, Christoph Schempp

JBO, Vol. 20, Issue 05, 051013, (December 2014) https://doi.org/10.1117/12.10.1117/1.JBO.20.5.051013

KEYWORDS: Skin, Microscopy, Laser scanners, Reflectivity, Inflammation, Confocal microscopy, Luminescence, Seaborgium, In vivo imaging, Capillaries

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SPIE Journal Paper | 13 November 2014 Open Access

Penetration of silver nanoparticles into porcine skin ex vivo using fluorescence lifetime imaging microscopy, Raman microscopy, and surface-enhanced Raman scattering microscopy

Yongjian Zhu, Chun-Sik Choe, Sebastian Ahlberg, Martina Meinke, Alexiev Ulrike, Juergen Lademann, Maxim Darvin

JBO, Vol. 20, Issue 05, 051006, (November 2014) https://doi.org/10.1117/12.10.1117/1.JBO.20.5.051006

KEYWORDS: Silver, Skin, Raman spectroscopy, Microscopy, Fluorescence lifetime imaging, Confocal microscopy, Luminescence, Ear, Nanoparticles, Raman scattering

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SPIE Journal Paper | 28 June 2013 Open Access

Special Section Guest Editorial: Optical Methods of Imaging in the Skin

Jürgen Lademann

JBO, Vol. 18, Issue 06, 061201, (June 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.6.061201

KEYWORDS: Skin, Tissue optics, Optical imaging, Laser scanners, Microscopy, Sensors, Diagnostics, Optical spectroscopy, Spectroscopy, Raman spectroscopy

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SPIE Journal Paper | 1 March 2013 Open Access

In vivo detection of basal cell carcinoma: comparison of a reflectance confocal microscope and a multiphoton tomograph

Martina Ulrich, Marisa Klemp, Maxim Darvin, Karsten König, Jürgen Lademann, Martina Meinke

JBO, Vol. 18, Issue 06, 061229, (March 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.6.061229

KEYWORDS: Skin, Confocal microscopy, Reflectivity, Microscopes, In vivo imaging, Tissue optics, Tumors, Tissues, Collagen, Statistical analysis

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Proceedings Article | 22 February 2013 Paper

Combining multiphoton and CARS microscopy for skin imaging

H. Breunig, M. Weinigel, M. Kellner-Höfer, R. Bückle, M. Darvin, J. Lademann, K. König

Proceedings Volume 8588, 85880N (2013) https://doi.org/10.1117/12.2001985

KEYWORDS: Skin, CARS tomography, Imaging systems, In vivo imaging, Multiphoton microscopy, Biomedical optics, Tissue optics, Molecules, Microscopy, Second-harmonic generation

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Proceedings Article | 22 February 2013 Paper

New developments in clinical CARS

Martin Weinigel, Hans Georg Breunig, Marcel Kellner-Höfer, Rainer Bückle, Maxim Darvin, Juergen Lademann, Karsten König

Proceedings Volume 8588, 85881E (2013) https://doi.org/10.1117/12.2001855

KEYWORDS: Skin, CARS tomography, In vivo imaging, Tissue optics, Femtosecond phenomena, Signal detection, Biomedical optics, Luminescence, Imaging systems, Photonic crystal fibers

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SPIE Journal Paper | 20 February 2013 Open Access

Optical methods for noninvasive determination of carotenoids in human and animal skin

Maxim Darvin, Martina Meinke, Wolfram Sterry, Jürgen Lademann

JBO, Vol. 18, Issue 06, 061230, (February 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.6.061230

KEYWORDS: Skin, Raman spectroscopy, Reflectance spectroscopy, Tissue optics, Spectroscopy, Absorption, In vivo imaging, Raman scattering, Biomedical optics, Microscopy

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SPIE Journal Paper | 12 December 2012 Open Access

Analyses of the correlation between dermal and blood carotenoids in female cattle by optical methods

Julia Klein, Maxim Darvin, Martina Meinke, Florian Schweigert, Kerstin Müller, Jürgen Lademann

JBO, Vol. 18, Issue 06, 061219, (December 2012) https://doi.org/10.1117/12.10.1117/1.JBO.18.6.061219

KEYWORDS: Blood, Skin, Plasma, Biological research, Tissue optics, In vivo imaging, Statistical analysis, Reflectance spectroscopy, Spectroscopy, Magnesium

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SPIE Journal Paper | 15 June 2012 Open Access

Confocal laser-scanning microscopy of capillaries in normal and psoriatic skin

Rami Archid, Alexa Patzelt, Sufian Ahmad, Wolfram Sterry, Jürgen Lademann, Bernhard Lange-Asschenfeldt, Martina Ulrich, Eggert Stockfleth, Sandra Philipp

JBO, Vol. 17, Issue 10, 101511, (June 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.10.101511

KEYWORDS: Capillaries, Skin, Confocal microscopy, Microscopy, Laser therapeutics, Pathogens, Blood vessels, Blood circulation, Refractive index, Dermatology

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SPIE Journal Paper | 14 June 2012 Open Access

Noninvasive measurements of carotenoids in bovine udder by reflection spectroscopy

Julia Klein, Kerstin Muller, Maxim Darvin, Jürgen Lademann

JBO, Vol. 17, Issue 10, 101514, (June 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.10.101514

KEYWORDS: Skin, Reflectance spectroscopy, Spectroscopy, Raman spectroscopy, Blood, In vivo imaging, Biopsy, Plasma, Statistical analysis, Tissue optics

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SPIE Journal Paper | 14 May 2012 Open Access

Analysis of the efficiency of hair removal by different optical methods: comparison of Trichoscan, reflectance confocal microscopy, and optical coherence tomography

Monika Kuck, Sabine Schanzer, Martina Meinke, Joachim Fluhr, Jürgen Lademann, Martina Ulrich, Eggert Stockfleth, Natalie Garcia Bartels, Ulrike Blume-Peytavi, Martin Krah

JBO, Vol. 17, Issue 10, 101504, (May 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.10.101504

KEYWORDS: Optical coherence tomography, Skin, Reflectivity, Confocal microscopy, Tissue optics, Biomedical optics, Biological research, Image quality, Dermatology, Imaging systems

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Proceedings Article | 8 May 2012 Paper

Spectroscopic detection of chemotherapeutics and antioxidants

Ines Latka, Roman Grüner, Christian Matthäus, Benjamin Dietzek, W. Werncke, Jürgen Lademann, Jürgen Popp

Proceedings Volume 8427, 84272O (2012) https://doi.org/10.1117/12.921768

KEYWORDS: Skin, Raman spectroscopy, Cancer, Spectroscopy, Luminescence, Personal protective equipment, Oncology, CARS tomography, Tissues, Raman scattering

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The hand-foot-syndrome presents a severe dermal side-effect of chemotherapeutic cancer treatment. The cause of this side-effect is the elimination of systemically administered chemotherapeutics with the sweat. Transported to the skin surface, the drugs subsequently penetrate into the skin in the manner of topically applied substances. Upon accumulation of the chemotherapeutics in the skin the drugs destroy cells and tissue - in the same way as they are supposed to act in cancer cells. Aiming at the development of strategies to illuminate the molecular mechanism underlying the handfoot- syndrome (and, in a second step, strategies to prevent this severe side-effect), it might be important to evaluate the concentration and distribution of chemotherapeutics and antioxidants in the human skin. The latter can be estimated by the carotenoid concentration, as carotenoids serve as marker substances for the dermal antioxidative status.Following the objectives outlined above, this contribution presents a spectroscopic study aiming at the detection and quantification of carotenoids and selected chemotherapeutics in human skin. To this end, spontaneous Raman scattering and coherent anti-Stokes Raman scattering (CARS) microspectroscopy are combined with two-photon excited fluorescence. While the latter technique is Please verify that (1) all pages are present, (2) all figures are correct, (3) all fonts and special characters are correct, and (4) all text and figures fit within the red margin lines shown on this review document. Complete formatting information is available at http://SPIE.org/manuscripts Return to your MySPIE To Do List at http://myspie.org and approve or disapprove this submission. Your manuscript will not be published without this approval.restricted to the detection of fluorescent chemotherapeutics, e.g., doxorubicin, the vibrational spectroscopic techniques can - in principle - be applied to any type of analyte molecules. Furthermore, we will present the monitoring of doxorubicin uptake during experiments.

Proceedings Article | 8 May 2012 Paper

Discrimination of skin diseases using the multimodal imaging approach

N. Vogler, S. Heuke, D. Akimov, I. Latka, F. Kluschke, H.-J. Röwert-Huber, J. Lademann, B. Dietzek, J. Popp

Proceedings Volume 8427, 842710 (2012) https://doi.org/10.1117/12.921748

KEYWORDS: Tissues, Tumors, Second-harmonic generation, Skin, Collagen, Multimodal imaging, Signal detection, Cancer, Raman spectroscopy, Diagnostics

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Proceedings Article | 8 May 2012 Paper

Two-photon-excited autofluorescence and second-harmonic generation microscopy for the visualization of penetration of TiO2 and ZnO nanoparticles into human tooth tissue ex vivo

Natalia Trunina, Alexey Popov, Jürgen Lademann, Valery Tuchin, Risto Myllylä, Maxim Darvin

Proceedings Volume 8427, 84270Y (2012) https://doi.org/10.1117/12.924073

KEYWORDS: Nanoparticles, Teeth, Second-harmonic generation, Zinc oxide, Atrial fibrillation, Tissues, Ultrasonography, Microscopy, Visualization, Titanium dioxide

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SPIE Journal Paper | 1 October 2011 Open Access

Transfer of ultraviolet photon energy into fluorescent light in the visible path represents a new and efficient protection mechanism of sunscreens

Theognosia Vergou, Christina Antoniou, Alexa Patzelt, Heike Richter, Sabine Schanzer, Wolfram Sterry, Jürgen Lademann, Leonhard Zastrow, Karin Golz, Olivier Doucet

JBO, Vol. 16, Issue 10, 105001, (October 2011) https://doi.org/10.1117/12.10.1117/1.3631790

KEYWORDS: Ultraviolet radiation, Skin, Visible radiation, Luminescence, Sun, Spectroscopy, Absorption, Energy transfer, Laser scanners, Microscopy

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SPIE Journal Paper | 1 September 2011 Open Access

Optical coherent tomography: promising in vivo measurement of hair shaft cross section

Natalie Garcia Bartels, Karola Stieler, Ulrike Blume-Peytavi, Heike Richter, Alexa Patzelt, Jürgen Lademann

JBO, Vol. 16, Issue 09, 096003, (September 2011) https://doi.org/10.1117/12.10.1117/1.3626210

KEYWORDS: Optical coherence tomography, In vivo imaging, Tomography, Biomedical optics, Skin, Diagnostics, Microscopy, Tissues, In vitro testing, Tissue optics

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SPIE Journal Paper | 1 April 2011 Open Access

Application of optical methods to characterize textile materials and their influence on the human skin

Helene Strese, Monika Kuck, Sabine Schanzer, Heike Richter, Martina Meinke, Wolfram Sterry, Jürgen Lademann, Rainer Benken, Joachim Fluhr, Christian Benderoth, Gottfried Frankowski

JBO, Vol. 16, Issue 04, 046013, (April 2011) https://doi.org/10.1117/12.10.1117/1.3562978

KEYWORDS: Skin, Tissue optics, In vivo imaging, Optical coherence tomography, Microscopy, Haptic technology, Laser scanners, Biomedical optics, Dermatology, Physiology

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SPIE Journal Paper | 1 March 2011 Open Access

Kinetics of carotenoid distribution in human skin in vivo after exogenous stress: disinfectant and wIRA-induced carotenoid depletion recovers from outside to inside

Joachim Fluhr, Heike Richter, Wolfram Sterry, Jürgen Lademann, Maxim Darvin, Peter Caspers, J. Andre van der Pol

JBO, Vol. 16, Issue 03, 035002, (March 2011) https://doi.org/10.1117/12.10.1117/1.3555183

KEYWORDS: Skin, Raman spectroscopy, In vivo imaging, Spectroscopy, Microscopy, Confocal microscopy, Infrared radiation, Infrared spectroscopy, Tissue optics, Imaging spectroscopy

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Proceedings Article | 11 February 2011 Paper

Combining multiphoton and CARS microscopy for skin imaging

H. Breunig, M. Weinigel, J. Lademann, W. Sterry, I. Latka, B. Dietzek, J. Popp, K. König

Proceedings Volume 7903, 79031A (2011) https://doi.org/10.1117/12.874969

KEYWORDS: Skin, CARS tomography, Microscopy, Multiphoton microscopy, In vivo imaging, Picosecond phenomena, In vitro testing, Optical parametric oscillators, Luminescence, Tissues

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SPIE Journal Paper | 1 September 2010 Open Access

Influence of the absorption behavior of sunscreens in the short-wavelength UV range (UVB) and the long-wavelength UV range (UVA) on the relation of the UVB absorption to sun protection factor

Hans-Jürgen Weigmann, Sabine Schanzer, Christina Antoniou, Wolfram Sterry, Jürgen Lademann

JBO, Vol. 15, Issue 05, 055008, (September 2010) https://doi.org/10.1117/12.10.1117/1.3497047

KEYWORDS: Ultraviolet radiation, Absorption, Sun, Optical filters, Absorption filters, Spectroscopy, Skin, Statistical modeling, Dermatology, Physiology

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Proceedings Article | 18 May 2010 Paper

ZnO and TiO2 particles: a study on nanosafety and photoprotection

Alexey Popov, Xin Zhao, Andrei Zvyagin, Jürgen Lademann, Michael Roberts, Washington Sanchez, Alexander Priezzhev, Risto Myllylä

Proceedings Volume 7715, 77153G (2010) https://doi.org/10.1117/12.854561

KEYWORDS: Particles, Zinc oxide, Skin, Nanoparticles, Ultraviolet radiation, Absorption, In vivo imaging, Reflectivity, In vitro testing, Titanium dioxide

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Proceedings Article | 3 March 2010 Paper

In vivo detection of time-resolved singlet oxygen luminescence under PDT relevant conditions

Jan Schlothauer, Beate Röder, Steffen Hackbarth, Jürgen Lademann

Proceedings Volume 7551, 755106 (2010) https://doi.org/10.1117/12.839851

KEYWORDS: Oxygen, Luminescence, Skin, Picosecond phenomena, In vivo imaging, Photodynamic therapy, Photolysis, Signal processing, Diffusion, Quantum efficiency

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SPIE Journal Paper | 1 September 2009 Open Access

Risk assessment of the application of a plasma jet in dermatology

Jürgen Lademann, Heike Richter, Alena Alborova, D. Humme, Alexa Patzelt, Axel Kramer, K. D. Weltmann, B. Hartmann, C. Ottomann, J. W. Fluhr, P. Hinz, G. Hübner, O. Lademann

JBO, Vol. 14, Issue 05, 054025, (September 2009) https://doi.org/10.1117/12.10.1117/1.3247156

KEYWORDS: Plasma, Skin, Tissues, Dermatology, Ultraviolet radiation, Natural surfaces, In vivo imaging, Quartz, Temperature metrology, Ear

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SPIE Journal Paper | 1 September 2009 Open Access

Effects of a topically applied wound ointment on epidermal wound healing studied by in vivo fluorescence laser scanning microscopy analysis

Bernhard Lange-Asschenfeldt, Alena Alborova, Daniela Kruger-Corcoran, Alexa Patzelt, Heike Richter, Wolfram Sterry, Axel Kramer, Eggert Stockfleth, Jürgen Lademann

JBO, Vol. 14, Issue 05, 054001, (September 2009) https://doi.org/10.1117/12.10.1117/1.3213603

KEYWORDS: Wound healing, Skin, Tissues, Luminescence, In vivo imaging, Tissue optics, Laser scanners, Microscopy, Dermatology, Optical fibers

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Proceedings Article | 8 July 2009 Paper

Interaction of sunscreen TiO2 nanoparticles with skin and UV light: penetration, protection, phototoxicity

Alexey Popov, Jürgen Lademann, Alexander Priezzhev, Risto Myllylä

Proceedings Volume 7368, 736822 (2009) https://doi.org/10.1117/12.831573

KEYWORDS: Particles, Skin, Ultraviolet radiation, Nanoparticles, Silicon, In vitro testing, Glasses, Absorption, Sun, Titanium dioxide

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SPIE Journal Paper | 1 March 2009 Open Access

Strategy of topical vaccination with nanoparticles

Sascha Jung, Alexa Patzelt, Nina Otberg, Gisela Thiede, Wolfram Sterry, Jürgen Lademann

JBO, Vol. 14, Issue 02, 021001, (March 2009) https://doi.org/10.1117/12.10.1117/1.3080714

KEYWORDS: Skin, Luminescence, Nanoparticles, Biopsy, Ear, Confocal laser scanning microscopy, Particles, Microscopy, Dermatology, Physiology

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SPIE Journal Paper | 1 March 2009 Open Access

Determination of the cuticula thickness of human and porcine hairs and their potential influence on the penetration of nanoparticles into the hair follicles

Jürgen Lademann, Alexa Patzelt, Heike Richter, Christina Antoniou, Wolfram Sterry, Fanny Knorr

JBO, Vol. 14, Issue 02, 021014, (March 2009) https://doi.org/10.1117/12.10.1117/1.3078813

KEYWORDS: Particles, Skin, Nanoparticles, In vivo imaging, Scanning electron microscopy, Tissues, Dermatology, Ear, Biopsy, Physiology

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SPIE Journal Paper | 1 March 2009 Open Access

Qualitative detection of single submicron and nanoparticles in human skin by scanning transmission x-ray microscopy

Christina Graf, Martina Meinke, Qi Gao, Sabrina Hadam, Jörg Raabe, Wolfram Sterry, Ulrike Blume-Peytavi, Jürgen Lademann, Eckart Ruhl, Annika Vogt

JBO, Vol. 14, Issue 02, 021015, (March 2009) https://doi.org/10.1117/12.10.1117/1.3078811

KEYWORDS: Particles, Skin, Nanoparticles, Gold, X-ray microscopy, Silica, Transmission electron microscopy, Absorption, Tissues, Microscopy

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SPIE Journal Paper | 1 March 2009 Open Access

Raman spectroscopic analysis of the increase of the carotenoid antioxidant concentration in human skin after a 1-week diet with ecological eggs

Karoline Hesterberg, Jürgen Lademann, Alexa Patzelt, Wolfram Sterry, Maxim Darvin

JBO, Vol. 14, Issue 02, 024039, (March 2009) https://doi.org/10.1117/12.10.1117/1.3119257

KEYWORDS: Skin, Raman spectroscopy, Spectroscopy, Organisms, Ultraviolet radiation, Molecules, Biological research, Physiology, Sun, Dermatology

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SPIE Journal Paper | 1 March 2009 Open Access

Comparison of human and porcine skin for characterization of sunscreens

Hans-Jürgen Weigmann, Sabine Schanzer, Alexa Patzelt, Virginie Bahaban, Fabienne Durat, Wolfram Sterry, Jürgen Lademann

JBO, Vol. 14, Issue 02, 024027, (March 2009) https://doi.org/10.1117/12.10.1117/1.3103340

KEYWORDS: Skin, Ultraviolet radiation, Sun, Spectroscopy, Ear, Absorption, In vivo imaging, Optical filters, In vitro testing, Dermatology

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SPIE Journal Paper | 1 March 2009 Open Access

Effect of size of TiO2 nanoparticles applied onto glass slide and porcine skin on generation of free radicals under ultraviolet irradiation

Alexey Popov, Stefan Haag, Martina Meinke, Jürgen Lademann, Alexander Priezzhev, Risto Myllylä

JBO, Vol. 14, Issue 02, 021011, (March 2009) https://doi.org/10.1117/12.10.1117/1.3078802

KEYWORDS: Particles, Skin, Ultraviolet radiation, Glasses, Nanoparticles, Principal component analysis, In vitro testing, Absorption, Ear, Titanium dioxide

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SPIE Journal Paper | 1 July 2008 Open Access

One-year study on the variation of carotenoid antioxidant substances in living human skin: influence of dietary supplementation and stress factors

Maxim Darvin, Alexa Patzelt, Fanny Knorr, Ulrike Blume-Peytavi, Wolfram Sterry, Juergen Lademann

JBO, Vol. 13, Issue 04, 044028, (July 2008) https://doi.org/10.1117/12.10.1117/1.2952076

KEYWORDS: Skin, Raman spectroscopy, Organisms, In vivo imaging, Blood, Physiology, Dermatology, Defense and security, Defense systems, Spectroscopy

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Proceedings Article | 5 June 2008 Paper

Monte Carlo calculations of UV protective properties of emulsions containing TiO2, Si and SiO2 nanoparticles

Alexey Popov, Alexander Priezzhev, Jürgen Lademann, Risto Myllylä

Proceedings Volume 7022, 702211 (2008) https://doi.org/10.1117/12.804096

KEYWORDS: Particles, Silicon, Transmittance, Silica, Ultraviolet radiation, Reflectivity, Nanoparticles, Refractive index, Absorption, Titanium dioxide

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SPIE Journal Paper | 1 January 2008 Open Access

Clinical applicability of in vivo fluorescence confocal microscopy for noninvasive diagnosis and therapeutic monitoring of nonmelanoma skin cancer

Susanne Astner, Susanne Dietterle, Nina Otberg, Hans-Joachim Röwert-Huber, Eggert Stockfleth, Jürgen Lademann

JBO, Vol. 13, Issue 01, 014003, (January 2008) https://doi.org/10.1117/12.10.1117/1.2837411

KEYWORDS: Skin, Luminescence, Confocal microscopy, In vivo imaging, Confocal fluorescent microscopy, Tissue optics, Tumors, Visualization, Skin cancer, Tissues

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Excisional biopsies and routine histology remains the gold standard for the histomorphologic evaluation of normal and diseased skin. However, there is increasing interest in the development of noninvasive optical technologies for evaluation, diagnosis, and monitoring of skin disease in vivo. Fluorescent confocal microscopy is an innovative optical technology that has previously been used for morphologic evaluation of live human tissue. We evaluate the clinical applicability of a fluorescent confocal laser scanning microscope (FLSM) for a systematic evaluation of normal and diseased skin in vivo and in correlation with routine histology. A total of 40 patients were recruited to participate in the study. Skin sites of 10 participants with no prior history of skin disease served as controls and to evaluate topographic variations of normal skin in vivo. Thirty patients with a suspected diagnosis of nonmelanoma skin cancer were evaluated, whereby FLSM features of actinic keratoses (AK) and basal cell carcinoma (BCC) were recorded in an observational analysis. Selected BCCs were monitored for their skin response to topical therapy using Imiquimod as an immune-response modifier. A commercially available fluorescence microscope (OptiScan Ltd., Melbourne, Australia) was used to carry out all FLSM evaluations. Common FLSM features to AK and BCC included nuclear pleomorphism at the level of the granular and spinous layer and increased vascularity in the superficial dermal compartment. Even though the presence of superficial disruption and mere atypia of epidermal keratinocytes was more indicative of AK, the nesting of atypical basal cells, increased blood vessel tortuosity, and nuclear polarization were more typical for BCC. All diagnoses were confirmed by histology. FLSM allowed a monitoring of the local immune response following therapy with Imiquimod and demonstrated a continuous normalization of diseased skin on repeated evaluations over time. (Partial Abstract)

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SPIE Journal Paper | 1 January 2008 Open Access

Two-wavelength carbon dioxide laser application for in-vitro blood glucose measurements

Martina Meinke, Gerhard Müller, Hansjörg Albrecht, Christina Antoniou, H. Richter, Jürgen Lademann

JBO, Vol. 13, Issue 01, 014021, (January 2008) https://doi.org/10.1117/12.10.1117/1.2870093

KEYWORDS: Glucose, Blood, Gas lasers, Absorption, Carbon dioxide lasers, Carbon monoxide, FT-IR spectroscopy, Absorbance, Plasma, Temperature metrology

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Proceedings Article | 19 July 2007 Paper

Reconstruction of stratum corneum profile of porcine ear skin after tape stripping using UV/VIS spectroscopy

Alexey Popov, Jürgen Lademann, Alexander Priezzhev, Risto Myllylä

Proceedings Volume 6628, 66281S (2007) https://doi.org/10.1117/12.729525

KEYWORDS: Skin, Absorbance, Ear, Spectroscopy, In vivo imaging, Transmittance, Laser scanners, In vitro testing, Sodium, Luminescence

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SPIE Journal Paper | 1 July 2007 Open Access

Ex-vivo spectroscopic quantification of sunscreen efficacy: proposal of a universal sun protection factor

Hans-Jürgen Weigmann, Sabine Schanzer, Alexa Teichmann, F. Durat, Christina Antoniou, H. Schaefer, Wolfram Sterry, Jürgen Lademann

JBO, Vol. 12, Issue 04, 044013, (July 2007) https://doi.org/10.1117/12.10.1117/1.2753365

KEYWORDS: Sun, Ultraviolet radiation, Spectroscopy, Skin, Optical filters, In vivo imaging, Absorption, Absorbance, Injuries, Physiology

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Proceedings Article | 7 May 2007 Paper

Influence of multiple light-scattering on TiO2 nanoparticles imbedded into stratum corneum on light transmittance in UV and visible wavelength regions

Alexey Popov, Alexander Priezzhev, Jürgen Lademann, Risto Myllylä

Proceedings Volume 6535, 65351E (2007) https://doi.org/10.1117/12.740988

KEYWORDS: Particles, Scattering, Nanoparticles, Photons, Skin, Transmittance, Light scattering, Ultraviolet radiation, Mie scattering, Signal attenuation

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Proceedings Article | 26 April 2007 Paper

Monte Carlo study of skin optical clearing to enhance light penetration in the tissue

Alexey Bashkatov, Elina Genina, Valery Tuchin, Mikhail Stolnitz, Dmitry Zhestkov, Jürgen Lademann

Proceedings Volume 6535, 653514 (2007) https://doi.org/10.1117/12.740977

KEYWORDS: Skin, Scattering, Tissue optics, Optical clearing, Blood, Tissues, Refractive index, Glucose, Absorption, Light scattering

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Proceedings Article | 26 April 2007 Paper

Non-invasive in-vivo Raman spectroscopic measurement of the dynamics of the antioxidant substance lycopene in the human skin after a dietary supplementation

M. Darvin, I. Gersonde, H. Albrecht, W. Sterry, J. Lademann

Proceedings Volume 6535, 653502 (2007) https://doi.org/10.1117/12.740598

KEYWORDS: Skin, Raman spectroscopy, Organisms, In vivo imaging, Spectroscopy, Tissue optics, Imaging systems, Physiology, Laser applications, Ultraviolet radiation

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SPIE Journal Paper | 1 November 2006 Open Access

Investigation of the homogeneity of the distribution of sunscreen formulations on the human skin: characterization and comparison of two different methods

Alexa Teichmann, Marc Pissavini, Louis Ferrero, Adeline Dehais, Leonhard Zastrow, Heike Richter, Jürgen Lademann

JBO, Vol. 11, Issue 06, 064005, (November 2006) https://doi.org/10.1117/12.10.1117/1.2409291

KEYWORDS: Skin, In vivo imaging, Fourier transforms, Laser scanners, Sun, Microscopy, Ultraviolet radiation, Colorimetry, Confocal microscopy, Optical filters

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SPIE Journal Paper | 1 September 2006 Open Access

Penetration studies of topically applied substances: optical determination of the amount of stratum corneum removed by tape stripping

Jürgen Lademann, A. Ilgevicius, O. Zurbau, Hans-Dieter Liess, S. Schanzer, Hans-Jürgen Weigmann, Christina Antoniou, R. von Pelchrzim, Wolfram Sterry

JBO, Vol. 11, Issue 05, 054026, (September 2006) https://doi.org/10.1117/12.10.1117/1.2359466

KEYWORDS: Skin, Spectroscopy, Projection systems, Absorption, Dermatology, Adhesives, Mass spectrometry, Physiology, Testing and analysis, Lamps

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SPIE Journal Paper | 1 July 2006 Open Access

In vivo confocal scanning laser microscopy: comparison of the reflectance and fluorescence mode by imaging human skin

Lars Meyer, Nina Otberg, Wolfram Sterry, Jürgen Lademann

JBO, Vol. 11, Issue 04, 044012, (July 2006) https://doi.org/10.1117/12.10.1117/1.2337294

KEYWORDS: Skin, Confocal microscopy, Reflectivity, Luminescence, In vivo imaging, Microscopy, Tissues, Tissue optics, Dermatology, Image resolution

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SPIE Journal Paper | 1 January 2006 Open Access

Comparison of blood flow to the cutaneous temperature and redness after topical application of benzyl nicotinate

Ute Jacobi, Marco Kaiser, Jürgen Koscielny, Rijk Schuetz, Martina Meinke, Wolfram Sterry, Jürgen Lademann

JBO, Vol. 11, Issue 01, 014025, (January 2006) https://doi.org/10.1117/12.10.1117/1.2166370

KEYWORDS: Skin, Blood circulation, Temperature metrology, Doppler effect, Capillaries, Blood, Dermatology, Signal detection, Semiconductor lasers, Data modeling

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SPIE Journal Paper | 1 November 2005 Open Access

Effect of size of TiO₂ nanoparticles embedded into stratum corneum on ultraviolet-A and ultraviolet-B sun-blocking properties of the skin

Alexey Popov, Jürgen Lademann, Alexander Priezzhev, Risto Myllylä

JBO, Vol. 10, Issue 06, 064037, (November 2005) https://doi.org/10.1117/12.10.1117/1.2138017

KEYWORDS: Particles, Absorption, Scattering, Skin, Ultraviolet radiation, Light scattering, Nanoparticles, Monte Carlo methods, Refractive index, Titanium dioxide

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SPIE Journal Paper | 1 September 2005 Open Access

Optical investigations to avoid the disturbing influences of furrows and wrinkles quantifying penetration of drugs and cosmetics into the skin by tape stripping

Jürgen Lademann, Hans-Jürgen Weigmann, S. Schanzer, Heike Richter, Heike Audring, Christina Antoniou, G. Tsikrikas, Heiner Gers-Barlag, Wolfram Sterry

JBO, Vol. 10, Issue 05, 054015, (September 2005) https://doi.org/10.1117/12.10.1117/1.2055507

KEYWORDS: Skin, Tissue optics, Adhesives, Ultraviolet radiation, Optical coherence tomography, Microscopy, Biopsy, Biomedical optics, Absorption, Laser optics

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Proceedings Article | 22 June 2005 Paper

Efficiency of TiO2 nanoparticles of different sizes as UV-B light skin-protective fraction in sunscreens

Alexey Popov, Alexander Priezzhev, J. Lademann, Risto Myllyla

Proceedings Volume 5771, (2005) https://doi.org/10.1117/12.634664

KEYWORDS: Particles, Absorption, Skin, Scattering, Monte Carlo methods, Light scattering, Ultraviolet radiation, Refractive index, Nanoparticles, Titanium dioxide

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Proceedings Article | 7 June 2005 Paper

Control of optical properties of human skin by embedding light scattering nanoparticles

Alexey Popov, Alexander Priezzhev, Jurgen Lademann

Proceedings Volume 5850, (2005) https://doi.org/10.1117/12.633742

KEYWORDS: Particles, Absorption, Skin, Light scattering, Scattering, Monte Carlo methods, Ultraviolet radiation, Refractive index, Optical properties, Titanium dioxide

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Proceedings Article | 7 March 2005 Paper

Optical sensing of titanium dioxide nanoparticles within horny layer of human skin and their protecting effect against solar UV radiation

Alexey Popov, Mikhail Kirillin, Alexander Priezzhev, Jurgen Lademann, Jukka Hast, Risto Myllyla

Proceedings Volume 5702, (2005) https://doi.org/10.1117/12.590860

KEYWORDS: Particles, Optical coherence tomography, Skin, Absorption, Monte Carlo methods, Nanoparticles, Ultraviolet radiation, Scattering, Solar radiation, Titanium dioxide

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SPIE Journal Paper | 1 January 2005 Open Access

Determination of penetration profiles of topically applied substances by means of tape stripping and optical spectroscopy: UV filter substance in sunscreens

Hans-Jürgen Weigmann, Ute Jacobi, Christina Antoniou, G. Tsikrikas, Volker Wendel, Cladius Rapp, Heiner Gers-Barlag, Wolfram Sterry, Jürgen Lademann

JBO, Vol. 10, Issue 01, 014009, (January 2005) https://doi.org/10.1117/12.10.1117/1.1854683

KEYWORDS: Ultraviolet radiation, Optical filters, Spectroscopy, Absorbance, Skin, Absorption, Laser scanners, Absorption filters, Microscopy, Optical spectroscopy

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SPIE Journal Paper | 1 January 2005 Open Access

Synergy effects between organic and inorganic UV filters in sunscreens

Jürgen Lademann, S. Schanzer, Ute Jacobi, H. Schaefer, F. Pflücker, H. Driller, J. Beck, M. Meinke, Andre Roggan, Wolfram Sterry

JBO, Vol. 10, Issue 01, 014008, (January 2005) https://doi.org/10.1117/12.10.1117/1.1854112

KEYWORDS: Absorption, Skin, Scattering, Ultraviolet radiation, Photons, Tissue optics, In vitro testing, Silica, In vivo imaging, Particles

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Proceedings Article | 9 December 2004 Paper

Manipulation of optical properties of human skin by light scattering nanoparticles of titanium dioxide

Alexey Popov, Alexander Priezzhev, Jurgen Lademann, Risto Myllyla

Proceedings Volume 5578, (2004) https://doi.org/10.1117/12.567423

KEYWORDS: Particles, Absorption, Skin, Monte Carlo methods, Scattering, Light scattering, Ultraviolet radiation, Anisotropy, Refractive index, Optical properties

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SPIE Journal Paper | 1 November 2004 Open Access

Influence of nonhomogeneous distribution of topically applied UV filters on sun protection factors

Jürgen Lademann, Andreas Rudolph, Ute Jacobi, Hans-Jürgen Weigmann, Hans Schaefer, Wolfram Sterry

JBO, Vol. 9, Issue 06, (November 2004) https://doi.org/10.1117/12.10.1117/1.1805557

KEYWORDS: Skin, Tissue optics, Ultraviolet radiation, In vivo imaging, Optical filters, Sun, In vitro testing, Laser scanners, Microscopy, UV optics

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Proceedings Article | 20 August 2004 Paper

Raman spectroscopic measurements of beta-carotene and lycopene in human skin

M. Darvin, I. Gerzonde, S. Ey, Nikolai Brandt, Hansjoerg Albrecht, Sergei Gonchukov, Wolfram Sterry, Juergen Lademann

Proceedings Volume 5474, (2004) https://doi.org/10.1117/12.578308

KEYWORDS: Raman spectroscopy, Skin, Molecules, Spectroscopy, Oxygen, In vivo imaging, Optical imaging, Imaging systems, Tissues, Absorption

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SPIE Journal Paper | 1 March 2004 Open Access

Noninvasive selective detection of lycopene and β-carotene in human skin using Raman spectroscopy

Igor Ermakov, Maia Ermakova, Werner Gellermann, Jürgen Lademann

JBO, Vol. 9, Issue 02, (March 2004) https://doi.org/10.1117/12.10.1117/1.1646172

KEYWORDS: Skin, Raman spectroscopy, Molecules, Absorption, Carbon, Tissues, Luminescence, Raman scattering, Tissue optics, Argon ion lasers

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Proceedings Article | 13 October 2003 Paper

Application of in vivo laser scanning microscope in dermatology

Juergen Lademann, H. Richter, N. Otberg, F. Lawrenz, U. Blume-Peytavi, W. Sterry

Proceedings Volume 5068, (2003) https://doi.org/10.1117/12.518622

KEYWORDS: Skin, In vivo imaging, Laser scanners, Dermatology, Microscopes, Microscopy, In vitro testing, Tissue optics, Biopsy, Physiology

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SPIE Journal Paper | 1 October 2003 Open Access

Quantification of the horny layer using tape stripping and microscopic techniques

Ulrich Lindemann, Kathrin Wilken, Hans-Jürgen Weigmann, Hans Schaefer, Wolfram Sterry, Jürgen Lademann

JBO, Vol. 8, Issue 04, (October 2003) https://doi.org/10.1117/12.10.1117/1.1609200

KEYWORDS: Skin, Microscopy, Ultraviolet radiation, Laser scanners, Spectroscopy, Adhesives, Ear, Microscopes, Optical filters, Phase contrast

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Proceedings Article | 23 July 2003 Paper

In vitro glucose measurements using a two-wavelength CO2 laser

Juergen Lademann, Heike Richter, Martina Meinke, Gerhard Mueller, Pavel Kapustin, Victor Masychev, Yuri Bulkin, Klaus Berndt, Wolfram Sterry

Proceedings Volume 4965, (2003) https://doi.org/10.1117/12.485581

KEYWORDS: Glucose, Blood, Absorption, FT-IR spectroscopy, Carbon dioxide lasers, Plasma, Statistical analysis, Temperature metrology, Absorbance, Crystals

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Proceedings Article | 16 July 2002 Paper

Optical methods for the analysis of dermatopharmacokinetics

Juergen Lademann, Hans-Juergen Weigmann, R. von Pelchrzim, Wolfram Sterry

Proceedings Volume 4707, (2002) https://doi.org/10.1117/12.475577

KEYWORDS: Skin, Spectroscopy, Absorbance, Tissue optics, Biological research, Physiology, Ultraviolet radiation, Luminescence, Statistical analysis, Titanium dioxide

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Proceedings Article | 13 June 2001 Paper

Diagnostic potential of erythrocytes aggregation and sedimentation measurements in whole blood samples

Juergen Lademann, Heike Richter, W. Sterry, Alexander Priezzhev

Proceedings Volume 4263, (2001) https://doi.org/10.1117/12.429328

KEYWORDS: Blood, Signal processing, Statistical analysis, Diagnostics, Proteins, Optical testing, Light scattering, Scatter measurement, Data processing, Sensors

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Proceedings Article | 31 May 2000 Paper

Investigation of the aggregation and disaggregation properties of erythrocytes by light-scattering measurements

Juergen Lademann, Hans-Juergen Weigmann, Wolfram Sterry, Holger Kiesewetter, Andre Roggan, Gerhard Mueller, Alexander Priezzhev, Nikolai Firsov

Proceedings Volume 3923, (2000) https://doi.org/10.1117/12.387142

KEYWORDS: Blood, Signal processing, Signal detection, Statistical analysis, Laser spectroscopy, Cancer, Spectroscopy, Data processing, Visible radiation, Glasses

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Proceedings Article | 28 April 2000 Paper

Analysis of the penetration process of drugs and cosmetic products into the skin by tape stripping in combination with spectroscopic measurements

Juergen Lademann, Hans-Juergen Weigmann, Wolfram Sterry, Valery Tuchin, Dmitry Zimnyakov, G. Mueller, Hans Schaefer

Proceedings Volume 3915, (2000) https://doi.org/10.1117/12.384156

KEYWORDS: Absorbance, Skin, Spectroscopy, Laser scanners, Particles, Spatial frequencies, Fractal analysis, Microscopy, Statistical analysis, Scattering

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Proceedings Article | 17 May 1999 Paper

Assessment of erythrocyte aggregation in whole blood samples by light backscattering: clinical applications

Alexander Priezzhev, Nikolai Firsov, Marina Vyshlova, Juergen Lademann, Heike Richter, Holger Kiesewetter, Gerhard Mueller

Proceedings Volume 3599, (1999) https://doi.org/10.1117/12.348368

KEYWORDS: Blood, Rheumatology, Signal processing, Backscatter, Pathology, Optical diagnostics, Diagnostics, Therapeutics, Light scattering, Blood circulation

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Proceedings Article | 5 February 1999 Paper

Laser spectroscopic investigation of radical formation during laser-tissue interaction

J. Lademann, Hans-Juergen Weigmann, Wolfram Sterry, Gerhard Mueller

Proceedings Volume 3732, (1999) https://doi.org/10.1117/12.340028

KEYWORDS: Laser tissue interaction, Laser spectroscopy, Oxygen, Spectroscopy, Laser therapeutics, Laser cutting, Luminescence, Laser applications, Gas lasers, Carbon dioxide lasers

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Proceedings Article | 5 December 1996 Paper

Permanent gases and highly volatile organic compounds in laser plume

Hans-Juergen Weigmann, Juergen Lademann, H. Meffert, Wolfram Sterry

Proceedings Volume 2923, (1996) https://doi.org/10.1117/12.260737

KEYWORDS: Laser tissue interaction, Gases, Carbon dioxide lasers, Chemical reactions, Continuous wave operation, Oxygen, Laser spectroscopy, Excimer lasers, Aerosols, Industrial chemicals

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Proceedings Article | 5 December 1996 Paper

Radical formation during laser-tissue interaction

Juergen Lademann, Hans-Juergen Weigmann, H. Meffert, Wolfram Sterry

Proceedings Volume 2923, (1996) https://doi.org/10.1117/12.260736

KEYWORDS: Laser tissue interaction, Laser cutting, Laser spectroscopy, Luminescence, Laser therapeutics, Pulsed laser operation, Oxygen, Spectroscopy, Continuous wave operation, Laser applications

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Proceedings Article | 10 January 1996 Paper

Detection of hydrocarbon chlorides in the laser plume during laser treatment of tissue in medicine by an ion mobility drift sensor

Juergen Lademann, Hans-Dieter Liess, Juergen Leonhardt, W. Rohrbeck, H. Bensch, Hans-Juergen Weigmann

Proceedings Volume 2624, (1996) https://doi.org/10.1117/12.229554

KEYWORDS: Ions, Laser tissue interaction, Sensors, Spectroscopy, Laser cutting, Chlorine, Electrodes, Medicine, Laser therapeutics, Laser spectroscopy

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Proceedings Article | 10 January 1996 Paper

Characterization of laser tissue interaction processes by laser spectroscopic measurements

Juergen Lademann, Hans-Juergen Weigmann, Heike Audring, Wolfram Sterry, H. Meffert

Proceedings Volume 2624, (1996) https://doi.org/10.1117/12.229553

KEYWORDS: Laser tissue interaction, Laser spectroscopy, Spectroscopy, Aerosols, Carbon dioxide lasers, Excimer lasers, Luminescence, Laser processing, Chemical species, Carbon dioxide

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Proceedings Article | 10 January 1996 Paper

Optimization of tissue interaction in electrosurgery

Helmut Wurzer, Rainer Maeckel, Juergen Lademann, Hans-Juergen Weigmann, Heike Audring, Hans-Dieter Liess

Proceedings Volume 2624, (1996) https://doi.org/10.1117/12.229568

KEYWORDS: Tissues, Electrodes, In vitro testing, Connective tissue, Nerve, Automatic control, Tissue optics, Adsorption, Structured optical fibers, Natural surfaces

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Proceedings Article | 10 January 1996 Paper

Characterization of laser-tissue interaction processes by low-boiling emitted substances

Hans-Juergen Weigmann, Juergen Lademann, Ulrike Serfling, W. Lehnert, Wolfram Sterry, H. Meffert

Proceedings Volume 2624, (1996) https://doi.org/10.1117/12.229552

KEYWORDS: Laser tissue interaction, Carbon dioxide lasers, Continuous wave operation, Tissues, Magnesium, Laser processing, Laser therapeutics, Systems modeling, Gas lasers, Chlorine

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Proceedings Article | 18 January 1995 Paper

Dependence of laser plume components on different laser-tissue interaction processes

Hans-Juergen Weigmann, Juergen Lademann, Ulrike Serfling

Proceedings Volume 2323, (1995) https://doi.org/10.1117/12.199233

KEYWORDS: Laser tissue interaction, Carbon monoxide, Oxygen, Carbon dioxide lasers, Bone, Gases, Laser processing, Tissues, Continuous wave operation, Oxidation

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Proceedings Article | 18 January 1995 Paper

Investigation of laser-tissue interaction in medicine by means of laser spectroscopic measurements

Juergen Lademann, Hans-Juergen Weigmann

Proceedings Volume 2323, (1995) https://doi.org/10.1117/12.199235

KEYWORDS: Laser tissue interaction, Luminescence, Laser spectroscopy, Carbon dioxide lasers, Spectroscopy, Laser therapeutics, Continuous wave operation, Tissues, Laser processing, Molecular lasers

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Proceedings Article | 18 January 1995 Paper

Process controlling of a high-frequency cauter during tissue treatment

Helmut Wurzer, Rainer Maeckel, Juergen Lademann, Hans-Dieter Liess

Proceedings Volume 2323, (1995) https://doi.org/10.1117/12.199242

KEYWORDS: Tissues, Electrodes, Control systems, Process control, Surgery, Heterojunctions, Power supplies, Wound healing, Skin, Combustion

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Proceedings Article | 15 February 1994 Paper

New type of miniaturized drift sensor and its application in laser medicine

Hans-Dieter Liess, Juergen Lademann, Juergen Leonhardt, Dieter Berger

Proceedings Volume 2085, (1994) https://doi.org/10.1117/12.168755

KEYWORDS: Sensors, Ions, Ionization, Laser therapeutics, Electrodes, Spectroscopy, Molecules, Ultraviolet radiation, Laser tissue interaction, Process control

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Proceedings Article | 1 February 1994 Paper

Characterization of laser-tissue interaction by laser plume species

Hans-Juergen Weigmann, Juergen Lademann, Jochen Liebetruth

Proceedings Volume 2077, (1994) https://doi.org/10.1117/12.168042

KEYWORDS: Laser tissue interaction, Plasma, Carbon monoxide, Laser cutting, Oxygen, Gas lasers, Bone, Laser therapeutics, Carbon dioxide lasers, Nitrogen

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Proceedings Article | 1 February 1994 Paper

Laser spectroscopic detection of molecules and radicals during laser-tissue interaction in laser plumes

Juergen Lademann, Hans-Juergen Weigmann

Proceedings Volume 2077, (1994) https://doi.org/10.1117/12.168049

KEYWORDS: Laser tissue interaction, Luminescence, Laser spectroscopy, Plasma, Spectroscopy, Excimer lasers, Laser therapeutics, Bone, Molecules, Molecular spectroscopy

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Showing 5 of 87 publications

Conference Committee Involvement (38)

Dynamics and Fluctuations in Biomedical Photonics XXII

25 January 2025 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics XXI

28 January 2024 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics XX

29 January 2023 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics XIX

22 January 2022 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics XVIII

6 March 2021 | Online Only, California, United States

Dynamics and Fluctuations in Biomedical Photonics XVII

1 February 2020 | San Francisco, California, United States

Optical Diagnostics and Sensing XIX: Toward Point-of-Care Diagnostics

4 February 2019 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics XVI

2 February 2019 | San Francisco, California, United States

Optical Diagnostics and Sensing XVIII: Toward Point-of-Care Diagnostics

29 January 2018 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics XV

28 January 2018 | San Francisco, California, United States

Optical Diagnostics and Sensing XVII: Toward Point-of-Care Diagnostics

30 January 2017 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics XIV

29 January 2017 | San Francisco, California, United States

Optical Diagnostics and Sensing XVI: Toward Point-of-Care Diagnostics

15 February 2016 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics XIII

14 February 2016 | San Francisco, California, United States

Optical Diagnostics and Sensing XV: Toward Point-of-Care Diagnostics

10 February 2015 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics XII

7 February 2015 | San Francisco, California, United States

Optical Diagnostics and Sensing XIV: Toward Point-of-Care Diagnostics

3 February 2014 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics XI

1 February 2014 | San Francisco, California, United States

Optical Diagnostics and Sensing XIII: Toward Point-of-Care Diagnostics

6 February 2013 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics X

2 February 2013 | San Francisco, California, United States

Optical Diagnostics and Sensing XII: Toward Point-of-Care Diagnostics

25 January 2012 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics VII

22 January 2012 | San Francisco, California, United States

Optical Diagnostics and Sensing XI: Toward Point-of-Care Diagnostics

26 January 2011 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics VI

22 January 2011 | San Francisco, California, United States

Optical Diagnostics and Sensing X: Toward Point-of-Care Diagnostics

26 January 2010 | San Francisco, California, United States

Dynamics and Fluctuations in Biomedical Photonics VII

23 January 2010 | San Francisco, California, United States

Optical Diagnostics and Sensing IX

27 January 2009 | San Jose, California, United States

Dynamics and Fluctuations in Biomedical Photonics VI

24 January 2009 | San Jose, California, United States

Optical Diagnostics and Sensing VIII

23 January 2008 | San Jose, California, United States

Complex Dynamics and Fluctuations in Biomedical Photonics V

19 January 2008 | San Jose, California, United States

Optical Diagnostics and Sensing VII

23 January 2007 | San Jose, California, United States

Complex Dynamics and Fluctuations in Biomedical Photonics IV

20 January 2007 | San Jose, California, United States

Optical Diagnostics and Sensing VI

25 January 2006 | San Jose, California, United States

Complex Dynamics and Fluctuations in Biomedical Photonics III

21 January 2006 | San Jose, California, United States

Medical Imaging

1 September 2005 | Warsaw, Poland

Optical Diagnostics and Sensing V

25 January 2005 | San Jose, CA, United States

Optical Diagnostics and Sensing IV

27 January 2004 | San Jose, CA, United States

Optical Diagnostics and Sensing III

28 January 2003 | San Jose, CA, United States

Showing 5 of 38 Conference Committees

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