Plasmonics deals with understanding and manipulating the interaction between light and matter at a scale that is significantly smaller than the wavelength of light (e.g., metal nanoparticles), and chemical nanoplasmonics is mainly about the study and use of nanoscale chemistry for advancing plasmonics and the use of plasmonics to address key issues and challenges in chemistry and other related fields. Designing, synthesizing and controlling metal nanostructures with a superhigh precision for a large number of structures are the keys to the reliable and widespread use of plasmonic nanostructures in chemistry, materials science, optics, nanoscience, biotechnology and medicine. Here, I will share the design, synthetic strategies and characterization results of molecularly tunable and structurally reproducible plasmonic nanostructures including metal nanogap structures, multi-component metal nanoparticles and gold nanocatenanes with strong, controllable and quantifiable plasmonic signals (e.g., quantitative surface-enhanced Raman scattering). I will then show their potential in addressing some of important challenges in plasmonics, biosensing, bioimaging and therapeutics, and discuss h
Designing, synthesizing and controlling plasmonic metal nanostructures with a superhigh precision (nm or sub-nm precision) are of paramount importance for the reliable and widespread use of plasmonic nanostructures in optics, nanoscience, chemistry, materials science, energy and biotechnology. In particular, synthesizing plasmonic nanostructures, often with a nanogap, that can generate ultrastrong, controllable and quantifiable optical signals is the key to the practical use of plasmonic enhancement-based spectroscopies such as surface-enhanced Raman scattering (SERS), but has been highly challenging. Here, I will introduce the design, synthetic strategies and characterization of molecularly tunable and structurally reproducible plasmonically coupled and enhanced nanostructures (e.g., plasmonic nanogap structures) with strong, controllable and quantifiable plasmonic signals including SERS signals. I will then show their potential in addressing some of important challenges in plasmonics, biosensing, bioimaging and biocomputing including quantitative SERS and scalable DNA computing, and discuss how these new plasmonic materials and platforms can lead us to new breakthroughs in next-generation disease diagnostics including the liquid biopsies for early-stage cancers and infectious diseases.
Accurate measurement of Rayleigh scattering is crucially important for fundamental understanding of the plasmonic properties of meltimeric (≥ 3) nanoparticles that can be served as efficient SERS sensing platforms and nanophotonic materials. Thus, using the laser-scanning assisted dark-field microscopy that enabled to precisely collect far-field (Rayleigh) scattering from the centers of individual trimeric nanoparticles, we monitored spectral redistributions of oscillating coupled plasmonic modes as a function of trimer symmetry. As a consequence of the precise measurement of the polarization-resolved Rayleigh scattering spectra obtained from triangular trimers to linear trimers via elongated triangular trimers, the in-phase horizontally oscillating plasmonic mode with the largest dipole moment is found to be greatly increased by 20-folds, whereas the axially oscillating plasmonic mode with the second-largest dipole moment is dramatically decreased by 70-folds. Consequently, the overall quantity of the far-field scattering, the total sum of the individual coupled plasmonic modes, was gradually increased by 2-folds. The precise polarization-resolved Rayleigh scattering measurement also visualizes directly the directions of the radiation fields of individual oscillating coupled plasmonic modes, which would be valuable information in systematic controlling the polarization direction of the scattered light from the trimers. Overall, we showed an exemplary quantitative and extensive study of the coupled plasmonic modes from nanoparticles, giving a simple but clear insight.
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