Prof. Karsten König
Professor at JenLab GmbH
SPIE Involvement:
Fellow status | Conference Chair | Conference Program Committee | Editor | Author | Instructor
Area of Expertise:
multiphoton tomography , two photon microscopy , laser transfection , laser nanoprocessing , femtosecond laser , FLIM
Websites:
Profile Summary

Karsten König is C4 Full Professor and Head of the Department of Biophotonics and Laser Technologies at the Saarland University, Germany. He is also founder and president of the company JenLab GmbH with facilities in Jena and Saarbruecken.

He gained the PhD degree in physics as well as the habilitation degree in cell biology from the University Jena. Prof. König published about 500 scientific papers (2x Nature) in the field of biophotonics and laser material processing, filed 25 patents, and pioneered fluorescence lifetime imaging, femtosecond laser nanoprocessing, femtosecond laser transfection, and clinical multiphoton tomography.
His work was awarded with the SPIE Prism Award, the Leibinger Innovation Award, the Pascal Rol Award, the Award of the International Society of Skin Pharmacology and Physiology, the Technology for the Human Being Award of the Fraunhofer Society, the Kortum Motivation Prize, the Feulgen Prize, The New Economy Award, and the IAIR Award as European Man of the Year 2014.

His company JenLab sponsors the JenLab Young Investigator Award ($2000) that is presented during the annual Photonics West Conference in San Francisco as well as the Skin Imaging Award ($2000).

Karsten König focuses on biomedical and technical applications of femtosecond laser technology. His current projects include Sub-100nm-Nanomachining with 10 Femtosecond Laser Pulses, Optical Reprogramming by laser transfection, Testing the biosafety of nanoparticles in cosmetic products, and Multiphoton Tomography of astronauts to understand skin ageing effects in space.
Publications (202)

SPIE Conference Volume | May 17, 2017

PROCEEDINGS ARTICLE | February 21, 2017
Proc. SPIE. 10069, Multiphoton Microscopy in the Biomedical Sciences XVII
KEYWORDS: Breast, Second-harmonic generation, Oncology, Multiphoton microscopy, Atrial fibrillation, Cancer, Breast cancer, Tissues, Skin, Radiotherapy, Skin cancer, Fluorescence lifetime imaging, In vivo imaging, Harmonic generation

PROCEEDINGS ARTICLE | February 21, 2017
Proc. SPIE. 10069, Multiphoton Microscopy in the Biomedical Sciences XVII
KEYWORDS: Two photon imaging, Eye, Second-harmonic generation, Atrial fibrillation, Cornea, Tissues, Imaging systems, Luminescence, Collagen, Transplantation, Fluorescence lifetime imaging, In vivo imaging, Tissue optics, Two photon excitation microscopy, Multiphoton tomography

PROCEEDINGS ARTICLE | February 21, 2017
Proc. SPIE. 10069, Multiphoton Microscopy in the Biomedical Sciences XVII
KEYWORDS: Wound healing, Pathophysiology, Multiphoton microscopy, Skin, Medical research, Diagnostics, Biopsy, Inflammation, Tomography, Fluorescence lifetime imaging, Biological research, In vivo imaging, Multiphoton fluorescence microscopy, Multiphoton tomography

PROCEEDINGS ARTICLE | February 16, 2017
Proc. SPIE. 10068, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XV
KEYWORDS: Target detection, Microscopes, Femtosecond phenomena, Oscillators, Phase contrast, Green fluorescent protein, Imaging systems, Cameras, Luminescence, Laser irradiation, Genetics, Beam shaping, Stem cells, Optical manipulation, Camera shutters, Beam controllers

PROCEEDINGS ARTICLE | February 6, 2017
Proc. SPIE. 10037, Photonics in Dermatology and Plastic Surgery
KEYWORDS: Eye, Second-harmonic generation, Multiphoton microscopy, Atrial fibrillation, Skin, Microscopy, Collagen, Head, 3D metrology, Fluorescence lifetime imaging, In vivo imaging, Signal generators, Tissue optics, Multiphoton fluorescence microscopy

Showing 5 of 202 publications
Conference Committee Involvement (27)
Multiphoton Microscopy in the Biomedical Sciences XVIII
28 January 2018 | San Francisco, California, United States
Multiphoton Microscopy in the Biomedical Sciences XVII
29 January 2017 | San Francisco, California, United States
Multiphoton Microscopy in the Biomedical Sciences XVI
14 February 2016 | San Francisco, California, United States
Multiphoton Microscopy in the Biomedical Sciences XV
8 February 2015 | San Francisco, California, United States
Multiphoton Microscopy in the Biomedical Sciences XIV
2 February 2014 | San Francisco, California, United States
Showing 5 of 27 published special sections
Course Instructor
SC1092: Hands-on Multiphoton Tomography: From the Lab into the Clinics
Multiphoton Tomography based on two-photon fluorescence and second harmonic generation is a novel non-invasive method to obtain label-free optical tissue biopsies within seconds and with submicron resolution. The course provides deep insight into the basic mechanisms and performance of multiphoton tomographs as medical instruments. Expansion with CARS, FLIM, and OCT modules as well as applications in the field of cancer and stem cell detection, small animal imaging, and intratissue drug tracing (e.g. sunscreen nanoparticles) will also be discussed. Hands-on tissue studies will be demonstrated with a multiphoton tomograph.
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