Prof. Karsten König
Professor at JenLab GmbH
SPIE Involvement:
Fellow status | Conference Chair | Conference Program Committee | Author | Editor | Instructor
Area of Expertise:
multiphoton tomography , two photon microscopy , laser transfection , laser nanoprocessing , femtosecond laser , FLIM
Websites:
Profile Summary

Karsten König is C4 Full Professor and Head of the Department of Biophotonics and Laser Technologies at the Saarland University, Germany. He is also founder and president of the company JenLab GmbH with facilities in Jena and Saarbruecken.

He gained the PhD degree in physics as well as the habilitation degree in cell biology from the University Jena. Prof. König published about 500 scientific papers (2x Nature) in the field of biophotonics and laser material processing, filed 25 patents, and pioneered fluorescence lifetime imaging, femtosecond laser nanoprocessing, femtosecond laser transfection, and clinical multiphoton tomography.
His work was awarded with the SPIE Prism Award, the Leibinger Innovation Award, the Pascal Rol Award, the Award of the International Society of Skin Pharmacology and Physiology, the Technology for the Human Being Award of the Fraunhofer Society, the Kortum Motivation Prize, the Feulgen Prize, The New Economy Award, and the IAIR Award as European Man of the Year 2014.

His company JenLab sponsors the JenLab Young Investigator Award ($2000) that is presented during the annual Photonics West Conference in San Francisco as well as the Skin Imaging Award ($2000).

Karsten König focuses on biomedical and technical applications of femtosecond laser technology. His current projects include Sub-100nm-Nanomachining with 10 Femtosecond Laser Pulses, Optical Reprogramming by laser transfection, Testing the biosafety of nanoparticles in cosmetic products, and Multiphoton Tomography of astronauts to understand skin ageing effects in space.
Publications (212)

PROCEEDINGS ARTICLE | May 24, 2018
Proc. SPIE. 10679, Optics, Photonics, and Digital Technologies for Imaging Applications V
KEYWORDS: Second-harmonic generation, Cornea, Tissues, Skin, Luminescence, Fluorescence lifetime imaging, In vivo imaging, Tissue optics, Multiphoton tomography

SPIE Conference Volume | April 11, 2018

PROCEEDINGS ARTICLE | March 14, 2018
Proc. SPIE. 10498, Multiphoton Microscopy in the Biomedical Sciences XVIII
KEYWORDS: Two photon imaging, Femtosecond phenomena, Medicine, Multiphoton microscopy, Microscopy, Fluorescent markers, Fluorescence lifetime imaging, Stem cells, Tissue optics, Viruses

PROCEEDINGS ARTICLE | March 14, 2018
Proc. SPIE. 10467, Photonics in Dermatology and Plastic Surgery 2018
KEYWORDS: Two photon imaging, Femtosecond phenomena, Multiphoton microscopy, Cancer, Skin, Diagnostics, Melanoma, Tomography, Fluorescence lifetime imaging, In vivo imaging

SPIE Journal Paper | March 2, 2018
JBO Vol. 23 Issue 03
KEYWORDS: Cornea, Pathology, Collagen, Second-harmonic generation, Two photon imaging, Optical fibers, Mode conditioning cables, Microscopes, Statistical analysis, Diagnostics

PROCEEDINGS ARTICLE | February 23, 2018
Proc. SPIE. 10498, Multiphoton Microscopy in the Biomedical Sciences XVIII
KEYWORDS: Second-harmonic generation, Tissues, Skin, Collagen, Laser scanners, In vivo imaging, Tissue optics, Photomicroscopy, Laser tissue interaction, Multiphoton tomography

Showing 5 of 212 publications
Conference Committee Involvement (28)
Multiphoton Microscopy in the Biomedical Sciences XIX
3 February 2019 | San Francisco, California, United States
Multiphoton Microscopy in the Biomedical Sciences XVIII
28 January 2018 | San Francisco, California, United States
Multiphoton Microscopy in the Biomedical Sciences XVII
29 January 2017 | San Francisco, California, United States
Multiphoton Microscopy in the Biomedical Sciences XVI
14 February 2016 | San Francisco, California, United States
Multiphoton Microscopy in the Biomedical Sciences XV
8 February 2015 | San Francisco, California, United States
Showing 5 of 28 published special sections
Course Instructor
SC1092: Hands-on Multiphoton Tomography: From the Lab into the Clinics
Multiphoton Tomography based on two-photon fluorescence and second harmonic generation is a novel non-invasive method to obtain label-free optical tissue biopsies within seconds and with submicron resolution. The course provides deep insight into the basic mechanisms and performance of multiphoton tomographs as medical instruments. Expansion with CARS, FLIM, and OCT modules as well as applications in the field of cancer and stem cell detection, small animal imaging, and intratissue drug tracing (e.g. sunscreen nanoparticles) will also be discussed. Hands-on tissue studies will be demonstrated with a multiphoton tomograph.
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