Bacteria, viruses and parasites elimination from human environment is one of the most important problem, extensively
studied by many groups. The growing resistance to commonly used disinfection and/or sterilization methods and
antibiotics, is one of the major problem in the health care sector. Nanomaterials with tailored antimicrobial features may
find applications in this field. One of the promising application of nanomaterials is the possibility to enhance the
antimicrobial photodynamic therapy (APDT), which combines a nontoxic photoactive dye - photosensitizer and
nanomaterials properties. This paper focused on the examination of optical and antibacterial properties of silica- and
titania-based nanopowders doped with silver and photosensitizer - Photolon. Various concentration of Photolon and
nanomaterials have been prepared in order to examine the fluorescence enhancement and resulting better antibacterial
activity. It was proved that the fluorescence intensity of Photolon increased, depending on silver concentration.
Antibacterial study showed that silver doped silica and titania nanoparticles revealed antibacterial activity, but in the
presence of Photolon, the antibacterial activity of materials is more effective.