In this paper, we report the results of an attempt to disperse MWCNTs in water and determine their biocompatibilities. The length of the MWCNTs was reduced by treating the acidic nanotube suspension with ultrasonic irradiation. Then, the cut nanotubes were size-separated into 670, 550 and 220 nm length by filtration using polycarbonate membrane filters. The neutrophils activity (TNF-α) of size-separated MWCNTs was low and confirmed biocompatible.
We report the preparation, properties and biocompatibility of multi-walled carbon nanotube (MWCNT) disk. Sintered Multi-walled carbon nanotube disk was fabricated by spark plasma sintering the MWCNT and phenol resin mixture by using the Spark Plasma System (SPS) under 1273 K and 80 MPa in vacuum. As the concentration of phenol resin in the sintered MWCNT disk increases, the bending strength and Young’s modulus increased. However, the inflammatory response was observed in the tissue exposed to the surface of the sintered MWCNT disk. This was believed due to the residual phenol resin in the disk. The result indicates that the disk has to be annealed at higher temperatures under inert gas atmosphere to perfectly convert phenol resin to graphitic materials.
Magnetic nanoparticles are considered for biomedical applications, such as the medium in magnetic resonance imaging, hyperthermia, drug delivery, and for the purification or classification of DNA or virus. The performance of magnetic nanoparticles in biomedical application such as hyperthermia depends very much on the magnetic properties, size and size distribution. We briefly described the basic idea behind their use in drug delivery, magnetic separation and hyperthermia and discussed the prerequisite properties magnetic particles for biomedical applications. Finally reported the synthesis and classification scheme to prepare magnetite (Fe3O4) nanoparticles with narrow size distribution for magnetic fluid hyperthermia.
Conference Committee Involvement (2)
Nanosensing: Materials and Devices II
23 October 2005 | Boston, MA, United States
Nanosensing: Materials and Devices
25 October 2004 | Philadelphia, Pennsylvania, United States