Non-circular orbits in cone-beam CT (CBCT) imaging are increasingly being studied for potential benefits in field-of-view, dose reduction, improved image quality, minimal interference in guided procedures, metal artifact reduction, and more. While modern imaging systems such as robotic C-arms are enabling more freedom in potential orbit designs, practical implementation on such clinical systems remains challenging due to obstacles in critical stages of the workflow, including orbit realization, geometric calibration, and reconstruction. In this work, we build upon previous successes in clinical implementation and address key challenges in the geometric calibration stage with a novel calibration method. The resulting workflow eliminates the need for prior patient scans or dedicated calibration phantoms, and can be conducted in clinically relevant processing times.
Metal artifacts have been a difficult challenge for cone-beam CT (CBCT), especially for intraoperative imaging. Metal surgical tools and implants are often present in the field of view and can attenuate X-rays so heavily that they essentially create a missing-data problem. Recently, an increasing number of intra-operative imaging systems such as robotic C-arms are capable of non-circular orbits for data acquisition. Such trajectories can potentially improve sampling and the degree of data completeness to solve the metal-induced missing-data problem, thereby reducing or eliminating the associated image artifacts. In this work, we extend our prior theoretical and experimental work and implement non-circular orbits for metal artifact reduction on a clinical robotic C-arm (Siemens Artis zeego). To maximize the potential for clinical translation, we restrict our implementation to standard built-in motion and data collection functions, also available on other zeego systems, and work within the physical constraints and limitations on positioning and motion. Customized software tools for data extraction, processing, calibration, and reconstruction are used. We demonstrate example non-circular orbits and the resulting image quality using a phantom containing pedicle screws for spine fixation. As compared with a standard circular CBCT orbit, these non-circular orbits exhibit significantly reduced metal artifacts. These results suggest a high potential for image quality improvements for intraoperative CBCT imaging when metal tools or implants are present in the field-of-view.
Many interventional procedures aim at changing soft tissue perfusion or blood flow. One problem at present is that soft tissue perfusion and its changes cannot be assessed in an interventional suite because cone-beam computed tomography is too slow (it takes 4–10 s per volume scan). In order to address the problem, we propose a novel method called IPEN for Intra-operative 4-dimensional soft tissue PErfusion using a standard x-ray system with No gantry rotation. In this simulation study, we provide a proof-of-concept that the core ideas work.
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