Dr. Kevin C. Zhou Profile

Dr. Kevin C. Zhou

Postdoc at Univ of California Berkeley

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Author

Publications (17)

Proceedings Article | 13 March 2024 Presentation

Fourier light field camera array mesoscope for video-rate 3D imaging

Clare Cook, Kevin Zhou, Roarke Horstmeyer

Proceedings Volume PC12857, PC1285704 (2024) https://doi.org/10.1117/12.3001897

KEYWORDS: Imaging arrays, Stereoscopy, Microscopes, Cameras, Objectives, Microscopy, Microlens array, Imaging systems, Image sensors, Image resolution

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Proceedings Article | 13 March 2024 Presentation

High-content multimodal in vivo imaging using a parallelized gigapixel scale microscope

Xi Yang, Aurélien Bègue, Mark Harfouche, Clare Cook, Kanghyun Kim, Kevin Zhou, Roarke Horstmeyer

Proceedings Volume PC12848, PC128480H (2024) https://doi.org/10.1117/12.3002079

KEYWORDS: Organisms, In vivo imaging, Microscopy, Neurological disorders, Biological imaging, Alzheimer's disease, Zoom lenses, Video, Parkinson disease, Motion models

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Proceedings Article | 13 March 2024 Presentation

High-throughput computational microscopy with diffractive multiplexing across a gigapixel sensor array

Kevin Zhou, Chaoying Gu, Grace Jiang, Nicholas Antipa, Roarke Horstmeyer, Laura Waller

Proceedings Volume PC12857, PC128570A (2024) https://doi.org/10.1117/12.3000876

KEYWORDS: Sensors, Detector arrays, Multiplexing, Microscopy, Microscopes, Diffractive optical elements, Point spread functions, Reconstruction algorithms, Inverse problems, Image sensors

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Proceedings Article | 13 March 2024 Presentation

Tomographic behavioral tracking of freely-moving model organisms with a hemispheric Fourier light field microscope

Kevin Zhou, Clare Cook, Archan Chakraborty, Joakim Jönsson, Kyung Chul Lee, Xi Yang, Shiqi Xu, Jennifer Bagwell, Donald Fox, Michel Bagnat, Roarke Horstmeyer

Proceedings Volume PC12848, PC128480M (2024) https://doi.org/10.1117/12.3000874

KEYWORDS: Organisms, Microscopes, Tomography, Algorithm development, 3D modeling, Detection and tracking algorithms, 3D tracking, 3D image processing, Reconstruction algorithms, Muscles

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Proceedings Article | 13 March 2024 Presentation

Line-scan phase-resolved synthetic wavelength LiDAR using an off-axis holographic approach

Jingkai Zhang, Joseph Izatt, Robert Trout, Jianwei Li, Julia Foust, Al-Hafeez Dhalla, Kevin Zhou

Proceedings Volume PC12830, PC128300E (2024) https://doi.org/10.1117/12.3002644

KEYWORDS: Holography, Line scan image sensors, LIDAR, Optical coherence, 3D image processing, Interferograms, Imaging technologies, Imaging systems, Coherence imaging, Switches

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SPIE Journal Paper | 4 March 2024 Open Access

Tensorial tomographic Fourier ptychography with applications to muscle tissue imaging

Shiqi Xu, Xi Yang, Paul Ritter, Xiang Dai, Kyung Chul Lee, Lucas Kreiss, Kevin Zhou, Kanghyun Kim, Amey Chaware, Jadee Neff, Carolyn Glass, Seung Ah Lee, Oliver Friedrich, Roarke Horstmeyer

AP, Vol. 6, Issue 02, 026004, (March 2024) https://doi.org/10.1117/12.10.1117/1.AP.6.2.026004

KEYWORDS: Muscles, Biological samples, Tissues, Tomography, Birefringence, Polarization, Image restoration, Light sources and illumination, Matrices, Biological imaging

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Proceedings Article | 11 August 2023 Presentation + Paper

High-throughput imaging across multiple spatial scales with the multi-camera array microscope (MCAM)

Lucas Kreiss, Kevin Zhou, Kanghyun Kim, Mark Harfouche, Shiqi Xu, Joakim Jönsson, Kyung Chul Lee, Clare Cook, Xi Yang, Paul Reamey, Veton Saliu, Gregor Horstmeyer, Roarke Horstmeyer

Proceedings Volume 12622, 126220S (2023) https://doi.org/10.1117/12.2675451

KEYWORDS: Cameras, Microscopes, Video, Image resolution, 3D image processing, Video microscopy, Stereoscopy, Lens arrays, Imaging systems

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Proceedings Article | 16 March 2023 Presentation

High-throughput tomographic fluorescence imaging with a synchronized camera array (Conference Presentation)

Kevin Zhou, Joakim Jönsson, Clare Cook, Kyung Chul Lee, Xi Yang, Shiqi Xu, Jennifer Bagwell, Archan Chakraborty, Donald Fox, Michel Bagnat, Roarke Horstmeyer

Proceedings Volume PC12390, PC123900C (2023) https://doi.org/10.1117/12.2649458

KEYWORDS: Tomography, Luminescence, Cameras, Organisms, 3D modeling, Objectives, Video, Signal attenuation, Reflectors, Reconstruction algorithms

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Proceedings Article | 15 March 2023 Presentation

Multi-modal imaging with a parallelized 16-gigapixel microscope (Conference Presentation)

Kanghyun Kim, Kevin Zhou, Mark Harfouche, Roarke Horstmeyer

Proceedings Volume PC12383, PC1238303 (2023) https://doi.org/10.1117/12.2649472

KEYWORDS: Microscopes, Multimodal imaging, Microscopy, Phase contrast, Luminescence, Light emitting diodes, Lenses, Image resolution, Diagnostics

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Proceedings Article | 7 March 2022 Presentation

3D optical coherence refraction tomography using a parabolic mirror

Kevin Zhou, Ryan McNabb, Ruobing Qian, Simone Degan, Al-Hafeez Dhalla, Sina Farsiu, Joseph Izatt

Proceedings Volume PC11948, PC119480W (2022) https://doi.org/10.1117/12.2611206

KEYWORDS: Optical coherence tomography, Tomography, Refraction, Coherence (optics), Mirrors, 3D modeling, Speckle, Resolution enhancement technologies, Visualization, Reconstruction algorithms

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Proceedings Article | 2 March 2022 Presentation

Real-time FMCW 3D imaging for various room-scale applications

Jingkai Zhang, Joseph Izatt, Ruobing Qian, Hafeez Dhalla, Kevin Zhou, Christian Viehland

Proceedings Volume PC11966, PC1196602 (2022) https://doi.org/10.1117/12.2609132

KEYWORDS: Stereoscopy, Cameras, Telescopes, Coherence imaging, Beam steering, Robot vision, Reflector telescopes, Reflectivity, Real time imaging, Optical instrument design

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Proceedings Article | 12 September 2021 Presentation

Imaging anisotropy with vectorial Fourier ptychography

Shiqi Xu, Xiang Dai, Xi Yang, Kevin Zhou, Pavan Konda, Roarke Horstmeyer

Proceedings Volume 11875, 118750F (2021) https://doi.org/10.1117/12.2598999

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Microscopic imaging of anisotropic samples has many important applications in cytopathology. The endogenous contrast from the polarization properties of a specimen, such as its birefringence, provides valuable diagnostic information for several deadly diseases, including cardiac amyloidosis and squamous cell carcinoma, for example. In the past, polarized light microscopy (PLM) has been widely used as a diagnostic tool during the clinical review. However, in analogy with the standard microscope, the PLM typically has a restricted spatial-bandwidth product (SBP). As a consequence, one can either image a large area with low resolution or see the details of a very small area of the sample at the resolutions required for accurate analysis. To address the SBP issue of the PLM, we propose a computational microscopy method, termed vectorial Fourier ptychography, to illuminate the specimen with polarized light from different angles and detects different polarization states of the diffracted light. By illuminating a specimen with plane waves from different angles, our vectorial Fourier ptychography method effectively modulates the high-spatial-frequency components of the specimen into lower frequencies that can be detected by the optical system. With a Jones calculus-based forward model and a second-order phase retrieval method, we can reconstruct high-resolution, wide field-of-view(FOV) amplitude, phase, birefringence, retardance, and diattenuation of the specimen. To assess the reconstruction accuracy of our method, we imaged polystyrene beads submerged in immersion oils of different refractive index, as well as monosodium urate crystals. Further, To validate the diattenuation reconstruction accuracy, we reconstruct a USAF resolution test chart with a half blocked by a linear polarizer. These experiments confirm quantitatively accurate reconstruction results with a 1.25 um full-pitch resolution over a FOV of 6.6 x 4.4 mm^2, which is 5 times higher than the native (brightfield) resolution of the non-computational optical system. Finally, we demonstrate our technique by producing high SBP polarization images of several anisotropic biologic samples, includes collagen tissue, congo red stained cardiac tissue, and a bean root sample.

Proceedings Article | 5 March 2021 Presentation

Snapshot 3D imaging with a gigapixel-scale multi-aperture microscope

Kevin Zhou, Colin Cooke, Jaehee Park, Pavan Konda, Mark Harfouche, Roarke Horstmeyer

Proceedings Volume 11649, 116490C (2021) https://doi.org/10.1117/12.2576903

KEYWORDS: Microscopes, Stereoscopy, Cameras, 3D metrology, Temporal resolution, 3D image processing, Tomography, Spatial resolution, Reconstruction algorithms, Imaging systems

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SPIE Journal Paper | 11 April 2019 Open Access

Unraveling the molecular nature of melanin changes in metastatic cancer

Kuk-Youn Ju, Simone Degan, Martin Fischer, Kevin Zhou, Xiaomeng Jia, Jin Yu, Warren Warren

JBO, Vol. 24, Issue 05, 051414, (April 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.5.051414

KEYWORDS: Particles, Melanoma, Cancer, Microscopy, Transmission electron microscopy, Oxidation, Hydrogen, Chemical analysis, Skin, Absorption

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Proceedings Article | 19 April 2017 Presentation

Stimulated Raman scattering (SRS) spectroscopic OCT (Conference Presentation)

Francisco Robles, Kevin Zhou, Martin Fischer, Warren Warren

Proceedings Volume 10053, 100530X (2017) https://doi.org/10.1117/12.2254829

KEYWORDS: Imaging spectroscopy, Optical coherence tomography, Spectroscopy, Raman spectroscopy, Molecular spectroscopy, Raman scattering, Tissues, Coherence (optics), Multiplexing, Tomography

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Proceedings Article | 27 April 2016 Presentation

OCT-based three-dimensional, three vector component imaging of cilia-driven fluid flow for developmental biology (Conference Presentation)

Brendan Huang, Kevin Zhou, Ute Gamm, Vineet Bhandari, Mustafa Khokha, Michael Choma

Proceedings Volume 9716, 97160J (2016) https://doi.org/10.1117/12.2211601

KEYWORDS: 3D image processing, Biology, Particles, Velocimetry, 3D metrology, Skin, Calibration, Medicine, Velocity measurements, Reconstruction algorithms

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Proceedings Article | 26 April 2016 Presentation

Particle streak velocimetry-OCT (PSV-OCT): a novel method for multi-vector component velocimetry of microscale flow physiology (Conference Presentation)

Kevin Zhou, Brendan Huang, Ute Gamm, Vineet Bhandari, Mustafa Khokha, Michael Choma

Proceedings Volume 9697, 96970F (2016) https://doi.org/10.1117/12.2214794

KEYWORDS: Particles, Velocimetry, Optical coherence tomography, Physiology, Microfluidics, Animal model studies, Microfluidic imaging, Image acquisition, Biological research, 3D modeling

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Showing 5 of 17 publications

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