Photoacoustic measurements are tested as a possible tool for non invasive quantification of Water/Collagen relative content in InterVertebral Discs (IVDs).
A multiphysics model was developed to model the increase in temperature during phototherapy treatment (PTT) in mouse brain. The model includes also a numerical model for Photoacoustic thermometer during the hyper- thermia therapy. The coupling of different physics was investigated.
In situ temperature monitoring with photoacoustic measurements is introduced in an integrated setup, specifically designed for photothermotherapy treatmentof the glioblastoma, aided by nanoparticles and HIFU blood-brain barrier opening.
This paper proposes a method for improving the localization and the quantification of the optical parameters in photoacoustic (PA) tomography of biological tissues that are intrinsically heterogeneous in both optical and acoustic properties. It is based on the exploitation of both the PA signal, generated by the heterogeneous optical structures, and the secondary acoustic echoes due to the interaction between a primary PA wave generated near the tissue surface and the heterogeneous acoustic structures. These secondary echoes can also be collected through proper measurements of the PA signals. The experimental procedure is presented along with the method to filter the signal and the reconstruction algorithm that includes the account of the acoustic information.
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