The mathematical model the hyperthermy of the multilayer biological structure under the effect of laser
emission is proposed. One allows to variate the electrophysical parameters of the biological structure (complex
parameter of refraction of the blood and blood corpuscles, epidermis, the upper layer of derma, the lower layer
of derma), the significant dimensions of the regular elements of the blood and to establish dependencies between
them and by the biophysical properties of the blood taking into account heating biological tissue under the
influence on its surface flow of the nonpolarized monochromatic radiation for the case in vivo.