The evolution of the field of nanotechnology has propelled humankind to the brink of an impending revolution, which will fundamentally impact every aspect of human life. While theory and experimentation are indeed critical to this future, simulation will play a key role in the shape of this future. To this end, the field of nanotechnology has required significant advances in the way cyberinfrastructure is utilized to derive scientific progress. To sustain and indeed fuel growth in nanotechnology requires a new generation of scientists, currently in middle and high schools and in colleges and universities, trained to think and perform across disciplinary barriers. The task of reaching these students and to capture their imagination requires a fundamental and systematic approach, that is positioned at the convergence point of nanotechnology, pedagogy, and cyberinfrastructure. The Network for Computational Nanotechnology (NCN), through its nanoHUB.org website, is leading a new charge in bridging nanotechnology discovery and learning. In this paper, we will use the nanoHUB.org as a case study to highlight how the nanoscale vision is impacting teaching and learning at various levels.