Dr. Laura Di Sieno Profile

Dr. Laura Di Sieno

SPIE Involvement:

Editorial Board Member: Biophotonics Discovery | Author

Publications (45)

Proceedings Article | 8 September 2023 Paper

Use of bioresorbable fibers for interstitial time-domain diffuse optical spectroscopy with fast-gating

Vamshi Damagatla, Nadia Boetti, Laura Di Sieno, Diego Pugliese, Davide Janner, Alberto Dalla Mora, Antonio Pifferi

Proceedings Volume 12628, 1262818 (2023) https://doi.org/10.1117/12.2670504

KEYWORDS: Absorption, Diffuse optical spectroscopy, Single photon avalanche diodes, Scattering, Liquids, Tissues, Optical fibers, Light scattering, Glasses, Water

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Proceedings Article | 9 August 2023 Paper

Towards time-domain diffuse optics with extreme photon rate

L. Di Sieno, T. Talala, E. Avanzi, I. Nissinen, J. Nissinen, A. Dalla Mora

Proceedings Volume 12628, 1262815 (2023) https://doi.org/10.1117/12.2669264

KEYWORDS: Diffuse optical imaging, Pulsed laser operation, Photon counting, Mammography, Light harvesting, Integrated optics, In vivo imaging, Heart, Equipment, Distortion

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Proceedings Article | 9 August 2023 Paper

Initial examples of the SOLUS multimodal potential

G. Maffeis, A. Pifferi, A. Dalla Mora, L. Di Sieno, R. Cubeddu, A. Tosi, E. Conca, A. Giudice, A. Ruggeri, S. Tisa, A. Flocke, B. Rosinski, J.-M. Dinten, M. Perriollat, C. Fraschini, J. Lavaud, S. Arridge, G. Di Sciacca, A. Farina, P. Panizza, E. Venturini, P. Gordebeke, P. Taroni

Proceedings Volume 12628, 1262807 (2023) https://doi.org/10.1117/12.2670430

KEYWORDS: Radio optics, Machine learning, Data processing, Absorption, Ultrasonography, Multimodal imaging, Elastography, Doppler tomography, Diffuse optical tomography, Critical dimension metrology

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Proceedings Article | 7 March 2023 Presentation + Paper

Evaluation of the timing performance of silicon photomultiplier detectors array and its preliminary application in fluorescence lifetime sensing and diffuse optics

E. Avanzi, A. Ghezzi, A. Farina, C. D'Andrea, A. Dalla Mora, L. Di Sieno

Proceedings Volume 12376, 123760N (2023) https://doi.org/10.1117/12.2648786

KEYWORDS: Fluorescence, Silicon photomultipliers, Prototyping, Detector arrays, Signal detection, Single photon detectors, Picosecond phenomena, Diffuse optical imaging, Absorption, Time correlated single photon counting

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Proceedings Article | 7 March 2023 Presentation + Paper

Breast lesion classification based on absorption and composition parameters: a look at SOLUS first outcomes

G. Maffeis, A. Pifferi, A. Dalla Mora, L. Di Sieno, R. Cubeddu, A. Tosi, E. Conca, A. Giudice, A. Ruggeri, S. Tisa, A. Flocke, B. Rosinski, J.-M Dinten, M. Perriollat, C. Fraschini, J. Lavaud, S. Arridge, G. Di Sciacca, A. Farina, P. Panizza, E. Venturini, P. Gordebeke, Paola Taroni

Proceedings Volume 12376, 123760K (2023) https://doi.org/10.1117/12.2648945

KEYWORDS: Breast, Absorption, Machine learning, Image segmentation, Diffuse optical tomography, Diffuse optical imaging, Data analysis, Breast cancer, Ultrasound transducers

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SPIE Journal Paper | 15 June 2022 Open Access

Multi-laboratory performance assessment of diffuse optics instruments: the BitMap exercise

Pranav Lanka, Lin Yang, David Orive-Miguel, Joshua Deepak Veesa, Susanna Tagliabue, Aleh Sudakou, Saeed Samaei, Mario Forcione, Zuzana Kovacsova, Anurag Behera, Thomas Gladytz, Dirk Grosenick, Lionel Hervé, Turgut Durduran, Karolina Bejm, Magdalena Morawiec, Michał Kacprzak, Piotr Sawosz, Anna Gerega, Adam Liebert, Antonio Belli, Ilias Tachtsidis, Frédéric Lange, Gemma Bale, Luca Baratelli, Sylvain Gioux, Alexander Kalyanov, Martin Wolf, Sanathana Konugolu-Venkata-Sekar, Marta Zanoletti, Ileana Pirovano, Michele Lacerenza, Lina Qiu, Edoardo Ferocino, Giulia Maffeis, Caterina Amendola, Lorenzo Colombo, Lorenzo Frabasile, Pietro Levoni, Mauro Buttafava, Marco Renna, Laura Di Sieno, Rebecca Re, Andrea Farina, Lorenzo Spinelli, Alberto Dalla Mora, Davide Contini, Paola Taroni, Alberto Tosi, Alessandro Torricelli, Hamid Dehghani, Heidrun Wabnitz, Antonio Pifferi

JBO, Vol. 27, Issue 07, 074716, (June 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.7.074716

KEYWORDS: Raster graphics, Optical properties, Diffuse optical imaging, Scattering, Imaging spectroscopy, Absorption, Tissue optics, Spectroscopes, Sensors, Oximetry

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Proceedings Article | 3 March 2022 Paper

Breaking the rules of time-domain diffuse optics: working with 1 cm2 SiPM and well-beyond the single-photon statistics

L. Di Sieno, E. Avanzi, F. Acerbi, A. Gola, M. Lacerenza, A. Behera, D. Contini, A. Dalla Mora

Proceedings Volume 11974, 119740A (2022) https://doi.org/10.1117/12.2608656

KEYWORDS: Photons, Sensors, Absorption, Microchannel plates, Scattering, Diffuse optical imaging, Chromium, Single photon detectors, Light harvesting, Solids

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Proceedings Article | 9 December 2021 Paper

Fast-gated digital silicon photomultiplier maximizes light harvesting and depth sensitivity in time-domain diffuse optics

Alberto Dalla Mora, Laura Di Sieno, Edoardo Ferocino, Enrico Conca, Vincenzo Sesta, Mauro Buttafava, Federica Villa, Franco Zappa, Davide Contini, Alessandro Torricelli, Paola Taroni, Alberto Tosi, Antonio Pifferi

Proceedings Volume 11920, 1192004 (2021) https://doi.org/10.1117/12.2614311

KEYWORDS: Photons, Light harvesting, Silicon photomultipliers, Diffuse optical imaging, Sensors, In vivo imaging, Digital photography, Optical signal processing, Picosecond phenomena, Tissues

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Proceedings Article | 9 December 2021 Paper

Silicon photomultiplier-based detection module with up to 1 cm2 area to push time-domain diffuse optics performances

Laura Di Sieno, Alberto Dalla Mora, Anurag Behera, Alberto Gola, Fabio Acerbi

Proceedings Volume 11920, 1192005 (2021) https://doi.org/10.1117/12.2615204

KEYWORDS: Sensors, Optical properties, In vivo imaging, Diffuse optical imaging, Signal detection, Light harvesting, Absorption, Silicon, Radiography, Radio optics

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Proceedings Article | 9 December 2021 Paper

Time-domain diffuse optics beyond pile-up limits: a simulation study based on relevant figures of merit

Elisabetta Avanzi, Laura Di Sieno, Anurag Behera, Davide Contini, Alberto Dalla Mora

Proceedings Volume 11920, 1192006 (2021) https://doi.org/10.1117/12.2615206

KEYWORDS: Chromium, Photons, Scattering, Diffuse optical imaging, Laser scattering, Distortion, Picosecond phenomena, Optical properties, Microchannel plates, Absorption

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Proceedings Article | 9 December 2021 Paper

SOLUS: a novel multimodal approach to ultrasound and diffuse optics imaging of breast cancer

Antonio Pifferi, Alberto Dalla Mora, Laura Di Sieno, Giulia Maffeis, Alberto Tosi, Enrico Conca, Vincenzo Sesta, Andrea Giudice, Alessandro Ruggeri, Simone Tisa, Alexander Flocke, Bogdan Rosinski, Jean-Marc Dinten, Mathieu Perriollat, Hélène Sportouche, Christophe Fraschini, Simon Arridge, Giuseppe Di Sciacca, Andrea Farina, Pietro Panizza, Elena Venturini, Peter Gordebeke, Pamela Zolda, Paola Taroni

Proceedings Volume 11920, 1192003 (2021) https://doi.org/10.1117/12.2614309

KEYWORDS: Tissues, Picosecond phenomena, Imaging systems, Ultrasonography, Diffuse optical imaging, Breast cancer, Mammography, Sensors, Multimodal imaging, Breast

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Proceedings Article | 5 March 2021 Presentation + Paper

SOLUS: an innovative multimodal imaging system to improve breast cancer diagnosis through diffuse optics and ultrasounds

Antonio Pifferi, Alberto Dalla Mora, Laura Di Sieno, Edoardo Ferocino, Alberto Tosi, Enrico Conca, Vincenzo Sesta, Andrea Giudice, Alessandro Ruggeri, Simone Tisa, Alexander Flocke, Bogdan Rosinski, Jean-Marc Dinten, Mathieu Perriollat, Christophe Fraschini, Hélène Sportouche, Simon Arridge, Giuseppe Di Sciacca, Andrea Farina, Pietro Panizza, Elena Venturini, Peter Gordebeke, Pamela Zolda, Paola Taroni

Proceedings Volume 11639, 116390C (2021) https://doi.org/10.1117/12.2576778

KEYWORDS: Ultrasonography, Multimodal imaging, Imaging systems, Diffuse optical imaging, Breast cancer, Tissue optics, Sensors, Picosecond phenomena, Transducers, Tomography

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Proceedings Article | 5 March 2021 Presentation + Paper

A multi-laboratory comparison of photon migration instruments and their performances: the BitMap exercise

Sri Rama Pranav Kumar Lanka, Lin Yang, David Orive-Miguel, Joshua Deepak Veesa, Susanna Tagliabue, Aleh Sudakou, Saeed Samaei, Mario Forcione, Zuzana Kovacsova, Anurag Behera, Thomas Gladytz, Dirk Grosenick, Lionel Hervé, Giuseppe Lo Presti, Lorenzo Cortese, Turgut Durduran, Karolina Bejm, Magdalena Morawiec, Piotr Sawosz, Michal Kacprzak, Anna Gerega, Adam Liebert, Antonio Belli, Ilias Tachtsidis, Frédéric Lange, Gemma Bale, Luca Baratelli, Sylvain Gioux, Alexander Kalyanov, Martin Wolf, Sanathana Konugolu Venkata Sekar, Marta Zanoletti, Ileana Pirovano, Michele Lacerenza, Lina Qiu, Edoardo Ferocino, Giulia Maffeis, Caterina Amendola, Lorenzo Colombo, Mauro Buttafava, Marco Renna, Laura Di Sieno, Rebecca Re, Andrea Farina, Lorenzo Spinelli, Alberto Dalla Mora, Davide Contini, Alessandro Torricelli, Alberto Tosi, Paola Taroni, Hamid Dehghani, Heidrun Wabnitz, Antonio Pifferi

Proceedings Volume 11639, 116390F (2021) https://doi.org/10.1117/12.2578521

KEYWORDS: Raster graphics, Photonic devices, Tissue optics, Spectroscopes, Oximetry, Optical components, Mammography, Imaging spectroscopy, Functional imaging

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Proceedings Article | 27 April 2020 Presentation

Time-resolved multispectral fluorescence imaging system based on compressed sensing (Conference Presentation)

Cosimo D'Andrea, Andrea Farina, Giulia Acconcia, Ivan Labanca, Laura Di Sieno, Andrea Bassi, Gianluca Valentini, Ivan Rech

Proceedings Volume 11386, 113860I (2020) https://doi.org/10.1117/12.2558713

KEYWORDS: Luminescence, Imaging systems, Multispectral imaging, Compressed sensing, Signal processing, Reconstruction algorithms, Biomedical optics, Ultrafast imaging, Ultrafast measurement systems, Multidimensional signal processing

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Proceedings Article | 24 February 2020 Presentation + Paper

Time-resolved multi-dimensional fluorescence imaging using a Digital-Micromirror-Device and a SPAD-array detector

A. Farina, L. Di Sieno, G. Acconcia, A. Gulinatti, G. Valentini, I. Rech, C. D'Andrea

Proceedings Volume 11243, 112430N (2020) https://doi.org/10.1117/12.2546881

KEYWORDS: Luminescence, Imaging systems, Sensors, Cameras, Digital micromirror devices, Image compression, Biomedical optics, Tissue optics, CCD cameras, Charge-coupled devices

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Proceedings Article | 22 July 2019 Paper

Multimaterial bioresorbable optical fibers for theranostics

Daniel Milanese, Diego Pugliese, Nadia Boetti, Stavros Pissadakis, Maria Konstantaki, Pavel Peterka, Laura Di Sieno, Duccio Gallichi-Nottiani, Joris Lousteau, Davide Janner

Proceedings Volume 11075, 110750S (2019) https://doi.org/10.1117/12.2527679

KEYWORDS: Optical fibers, Glasses, Fiber Bragg gratings, Sensors, Diffuse optical imaging, Biomedical optics, Breast, Single mode fibers, Temperature sensors, Oxides

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Proceedings Article | 22 July 2019 Paper

Solid heterogeneous phantoms for multimodal ultrasound and diffuse optical imaging: an outcome of the SOLUS project for standardization

Laura Di Sieno, Rinaldo Cubeddu, Hélène Sportouche, David Savéry, Sanathana Konugolu Venkata Sekar, Bogdan Rosinski, Andrea Farina, Edoardo Ferocino, Pranav Lanka, Paola Taroni, Antonio Pifferi, Alberto Dalla Mora

Proceedings Volume 11075, 1107516 (2019) https://doi.org/10.1117/12.2526645

KEYWORDS: Ultrasonography, Optical properties, Diffuse optical imaging, Silicon, Imaging systems, Solids, Multimodal imaging, Tissues, Absorption, Calibration

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