An experiment was performed to assess the effect of using a Helmet Mounted Display (HMD) versus a conventional computer monitor and joystick to perform an Unmanned Aerial Vehicle (UAV) sensor operator target search task. Eight subjects were evaluated on objective performance measures including their target detection accuracy and responses, in addition to subjective measures including workload, fatigue, situational awareness, and simulator sickness in both experimental conditions. Subjects were flown through a virtual world and asked to identify objects as targets, non-targets, or distractors. Results for objective measures indicated no difference in the operators' ability to accurately classify targets and non-targets. The subjects' ability to place the cursor on a target of interset (targeting accuracy), was, however, significantly better in the computer monitor condition than the HMD. The distance at which subjects could classify an object's identity was also significantly better in the computer monitor condition. Subjective measures showed no overall differences for sel-reported fatigue, workload, and situational awareness. A significant disadvantage, however, was found for the HMD with respect to self-reported nausea, disorientation, and oculomotor strain. Results are discussed in terms of their implications for the incorporation of HMDs into UAV ground control station operations.