This paper presents the design and optimization of an RF energy harvesting system from multiple sources. The RF power is harvested from four frequency bands representing five wireless systems, namely GSM, UMTS, DTV, Wi-Fi, and road tolling system. A Schottky diode model was developed based on which an RF-DC rectifier joined with a voltage multiplier circuits were designed. The simulation results of the complete RF harvesting system showed superior performance to similar state of the art systems. To further optimize the design, and to eliminate use of a non-standard CMOS process associated with Schottky diodes, the Schottky diode based rectifier was replaced by diode connected transistor configuration based on self-threshold cancellation (SVC) technique.