Statistical analysis of endoscopic optical coherence tomography (EOCT) surveillance of 78 patients with Barrett's
esophagus (BE) is presented in this study. The sensitivity of OCT device in retrospective open detection of early
malignancy (including high grade dysplasia and intramucosal adenocarcinoma (IMAC)) was 75%, specificity 82%,
diagnostic accuracy - 80%, positive predictive value- 60%, negative predictive value- 87%. In the open recognition of
IMAC sensitivity was 81% and specificity were 85% each. Results of a blind recognition with the same material were
similar: sensitivity - 77%, specificity 85%, diagnostic accuracy - 82%, positive predictive value- 70%, negative
predictive value- 87%. As the endoscopic detection of early malignancy is problematic, OCT holds great promise in
enhancing the diagnostic capability of clinical GI endoscopy.