Mesoscopic shot noise is not only probabilistic: it has features
which reflect quantum mechanical entanglement. We discuss recent proposals of orbital entanglement generation and detection in mesoscopic coherent conductors. Orbital entanglement avoids the difficulty of detecting spin and leads to simpler structures. Orbital entanglement schemes invoke two two-particle sources. The index of the source plays the role of a pseudo-spin. The rotation of qubits can be implemented with beam-splitters or even just quantum point contacts. Entanglement is detected via violation of a Bell inequality. The necessary correlations can be extracted from shot noise measurements. Possible two particle sources are Cooper pairs emitted from superconductors or even simpler electron-hole pairs generated at tunnel contacts or generated dynamically with the help of oscillating potentials.