Dr. Mateusz Scibor Profile

Dr. Mateusz Scibor

at Friedrich-Alexander Univ Erlangen Nürnberg

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Author

Publications (6)

SPIE Journal Paper | 1 October 1997 Open Access

Imaging spectroscopy of the human ocular fundus in vivo

Martin Hammer, Dietrich Schweitzer, Lutz Leistritz, Mateusz Scibor, Karl-Heinz Donnerhacke, Juergen Strobel

JBO, Vol. 2, Issue 04, (October 1997) https://doi.org/10.1117/12.10.1117/12.285093

KEYWORDS: Reflectivity, In vivo imaging, Eye, Confocal microscopy, Image resolution, Cameras, Absorbance, Charge-coupled devices, Spectroscopy, Imaging spectroscopy

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Proceedings Article | 5 December 1996 Paper

Simultaneous measurement of oxygen saturation and vessel diameter by imaging spectrometry

Dietrich Schweitzer, Lutz Leistritz, Martin Hammer, Ulrich Bartsch, Mateusz Scibor, J. Kraft, C. Muench, W. Vilser, E. Bareshova, P. Putsche

Proceedings Volume 2930, (1996) https://doi.org/10.1117/12.260862

KEYWORDS: Oxygen, Blood, Scattering, Spectroscopy, Reflectivity, Light scattering, Absorption, Imaging spectrometry, Eye, Veins

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Proceedings Article | 5 December 1996 Paper

Laser scanner ophthalmoscope with free selectable wavelength

Dietrich Schweitzer, B. Kalve, Lutz Leistritz, Mateusz Scibor, Martin Hammer

Proceedings Volume 2930, (1996) https://doi.org/10.1117/12.260863

KEYWORDS: Laser scanners, Eye, Absorbance, Sensors, Signal to noise ratio, Laser systems engineering, Reflectivity, Bragg cells, Multispectral imaging, Oxygen

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Proceedings Article | 10 January 1996 Paper

Local resolved spectroscopy at the human ocular fundus in vivo: technique and clinical examples

Martin Hammer, Dietrich Schweitzer, Mateusz Scibor

Proceedings Volume 2632, (1996) https://doi.org/10.1117/12.229577

KEYWORDS: Reflectivity, Absorption, Reflectometry, Spectrographs, Cameras, Macula, Eye models, CCD cameras, Spectroscopy, In vivo imaging

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Proceedings Article | 22 May 1995 Paper

Calibration-free measurement of the oxygen saturation in human retinal vessels

Dietrich Schweitzer, Lutz Leistritz, Martin Hammer, Mateusz Scibor, Ulrich Bartsch, Juergen Strobel

Proceedings Volume 2393, (1995) https://doi.org/10.1117/12.209850

KEYWORDS: Oxygen, Blood, Scattering, Reflectivity, Brain, Spectroscopy, Signal attenuation, In vitro testing, Calibration, In vivo imaging

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The detection of alterations in the microcirculation requires both the measurement of the blood-flow and the measurement of the oxygen saturation in whole blood. The basis for the non-invasive estimation of the oxygen saturation is the difference between extinction-spectra of hemoglobin and of oxyhemoglobin. Further in whole blood the scattering at the erythrocytes has to be taken into account. In principle spectral measurements at three neighboring wavelengths are sufficient for the calculation of the oxygen saturation, the concentration- thickness-geometry product and the scattering intensity. Caused by the maximal permissible exposure, the signal/noise ratio is very low in fundus reflectometry. But if the wavelength- range from 520 nm to 620 nm is evaluated, the requirement at the signal/noise ratio is reduced. This reduction corresponds to the square root of the number of discrete wavelengths at which the ocular fundus reflectance is measured. So the oxygen saturation can be calculated with an error lower than +/- 4%. For this purpose the extinction spectrum of whole blood is approximated by a model, including besides the above mentioned unknowns the spectral dependency of the scattering. The experimental arrangement for the measurement of the oxygen saturation is an imaging ophthalmo-spectrometer which allows reflectance measurements with a good spectral (< 3 nm) and local (> 3 micrometers ) resolution simultaneously at a vessel and in its neighborhood. The extinction of blood is calculated as the logarithm of the ratio of the reflectance of the neighborhood and of the vessel. In this calculation the influences of the ocular media, of the background and of eye movements are eliminated. The sensitivity of the detector system has to be very high in order to detect the light which is reflected at a dark background and travels through the blood. The new method was tested by a comparison the oxygen saturation of the blood in an arteriole and a venule in the brain of a piglet measured by reflectometry with the oxygen saturation of the left ventricular and the venous blood measured by a laboratory hemoximeter. First results of the measurement of the oxygen saturation in human retinal vessels are demonstrated.

Proceedings Article | 24 June 1993 Paper

Early diagnosis of substance-specific alterations in primary open-angle glaucoma by means of fundus spectrometry

Dietrich Schweitzer, Mateusz Scibor, Martin Hammer, Sabine Guenther

Proceedings Volume 1877, (1993) https://doi.org/10.1117/12.147532

KEYWORDS: Scattering, Reflectivity, Visualization, Nerve, Light scattering, Macula, Spectroscopy, Particles, Eye, Mass attenuation coefficient

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