Dr. Michael Murek Profile

Dr. Michael Murek

at Inselspital

SPIE Involvement:

Author

Publications (12)

Proceedings Article | 3 October 2023 Presentation + Paper

Complete Mueller polarimetry: do we need it for biological tissues diagnosis?

Tatiana Novikova, Jessica Ramella-Roman, Leonard Felger, Romain Gros, Ekkehard Hewer, Theoni Maragkou, Richard McKinley, Stefano Moriconi, Michael Murek, Angelo Pierangelo, Omar Rodríguez-Núñez, Irena Zubak, Philippe Schucht

Proceedings Volume 12690, 1269006 (2023) https://doi.org/10.1117/12.2689662

KEYWORDS: Mueller matrices, Polarimetry, Depolarization, Brain, Tissues, Neuroimaging, Diagnostics, Reflection, Nervous system

Read Abstract +

Proceedings Article | 11 August 2023 Paper

Partial Mueller polarimetry for the complete optical diagnosis of biological tissue

Proceedings Volume 12629, 1262902 (2023) https://doi.org/10.1117/12.2670094

KEYWORDS: Polarimetry, Tissues, Tissue optics, Mueller matrices, Biomedical optics, Polarization, Depolarization, Optical components, Imaging systems, Video

Read Abstract +

Proceedings Article | 23 March 2023 Presentation

Brain white matter fiber tracts identification using wide-field imaging Mueller polarimetry: Ex vivo studies in a surgery-like environment

Leonard Felger, Romain Gros, Theoni Maragkou, Richard McKinley, Stefano Moriconi, Michael Murek, Tatiana Novikova, Angelo Pierangelo, Omar Rodríguez-Núnez, Irena Zubak, Philippe Schucht

Proceedings Volume 12364, 1236406 (2023) https://doi.org/10.1117/12.2650106

KEYWORDS: Polarimetry, Brain, Tissues, Neuroimaging, Cavitation, Blood, Ultrasonics, Tumors, Natural surfaces, In vivo imaging

Read Abstract +

Proceedings Article | 15 March 2023 Presentation

Evaluation of light penetration depth for Imaging Mueller polarimeter operating in a visible wavelength range in reflection geometry: ex-vivo studies of healthy brain white matter (Conference Presentation)

Omar Rodríguez-Núñez, Leonard Felger, Romain Gross, Theoni Maragkou, Richard McKinley, Stefano Moriconi, Michael Murek, Angelo Pierangelo, Philippe Schucht, Irena Zubak, Tatiana Novikova

Proceedings Volume PC12382, PC1238209 (2023) https://doi.org/10.1117/12.2650008

KEYWORDS: Brain, Polarimetry, Tumors, Neuroimaging, Brain mapping, Tissue optics, Tissues, Surgery, Backscatter, Anisotropy

Read Abstract +

Proceedings Article | 15 March 2023 Presentation

Evolution of polarimetric parameters of cadaver brain tissue with time and formaldehyde fixation in wide-field Mueller matrix images (Conference Presentation)

Romain Gros, Leonard Felger, Theoni Maragkou, Richard Mckinley, Stefano Moriconi, Michael Murek, Tatiana Novikova, Omar Rodríguez-Núñez, Philippe Schucht, Irena Zubak, Angelo Pierangelo

Proceedings Volume PC12382, PC1238203 (2023) https://doi.org/10.1117/12.2645668

KEYWORDS: Brain, Tissues, Tissue optics, Polarimetry, Neuroimaging, Statistical analysis, Tumors, Image registration, Brain mapping, Anisotropy

Read Abstract +

Proceedings Article | 15 March 2023 Presentation

Denoising diffusion networks applied to Mueller polarimetric images of brain tissue (Conference Presentation)

Stefano Moriconi, Leonard Felger, Romain Gros, Ekkehard Hewer, Theoni Maragkou, Michael Murek, Tatiana Novikova, Omar Rodríguez-Núñez, Angelo Pierangelo, Philippe Schucht, Richard McKinley

Proceedings Volume PC12382, PC123820H (2023) https://doi.org/10.1117/12.2649820

KEYWORDS: Polarimetry, Denoising, Signal to noise ratio, Neuroimaging, Diffusion, Brain, Tissues, Polarization, Visualization, Signal attenuation

Read Abstract +

Proceedings Article | 15 March 2023 Presentation

Multi-domain cotraining for tissue segmentation in fixed and fresh brain tissue using Mueller polarimetry (Conference Presentation)

Richard McKinley, Leonard Felger, Romain Gros, Ekkehard Hewer, Theoni Maragkou, Stefano Moriconi, Michael Murek, Tatiana Novikova, Omar Rodrıguez-Nunez, Angelo Pierangelo, Philippe Schucht

Proceedings Volume PC12382, PC1238208 (2023) https://doi.org/10.1117/12.2649787

KEYWORDS: Tissues, Brain, Tissue optics, Polarimetry, Image segmentation, Neuroimaging, Visualization, Tumors, Surgery, Real time imaging

Read Abstract +

Proceedings Article | 6 March 2023 Presentation + Paper

Intraoperative laser speckle contrast imaging to visualize blood flow dynamics in neurosurgery

Alexis Dimanche, David Miller, Johannes Goldberg, Cedric Kissling, Timothy Müller, Mandy Müller, Michael Murek, David Bervini, Andreas Raabe, Andrew Dunn

Proceedings Volume 12368, 1236804 (2023) https://doi.org/10.1117/12.2647911

KEYWORDS: Laser speckle contrast imaging, Surgery, Blood circulation, Speckle, Microscopes, Neurosurgery, Visualization, Aneurysms

Read Abstract +

Proceedings Article | 20 May 2022 Presentation + Paper

Machine learning for white matter fibre tract visualization in the human brain via Mueller matrix polarimetric data

Richard McKinley, Leonard Felger, Ekkehard Hewer, Theoni Maragkou, Michael Murek, Tatiana Novikova, Omar Rodríguez-Núñez, Angelo Pierangelo, Philippe Schucht

Proceedings Volume 12136, 121360G (2022) https://doi.org/10.1117/12.2624465

KEYWORDS: Brain, Polarimetry, Neuroimaging, Tissues, Tumors, Image segmentation, Visualization, Machine learning, Data modeling, Surgery

Read Abstract +

A clear identification of the border between a brain tumor and surrounding healthy tissue during neurosurgery is essential in order to maximize tumor resection while preserving neurological function. However, tumor tissue is often difficult to differentiate from infiltrated brain during surgery. Most existing techniques have drawbacks in terms of cost, measurement time and accuracy. The fibre tracts of healthy brain white matter are composed of densely packed bundles of myelinated axons that form uniaxial linear birefringent medium with the optical axis oriented along the direction of the fibre bundle. Brain tumors, whose cells grow in a largely chaotic way, lack this anisotropy of refractive index. Therefore tumor tissue can be distinguished from of healthy white matter using polarized light. A wide-field visible wavelength imaging Mueller polarimetric system was used for the study of formalin-fixed human brain sections measured in reflection geometry. The non-linear decomposition of the Mueller matrices provided the maps of depolarization, scalar retardance and azimuth of the optical axis. A compelling correlation between the azimuth of the optical axis and the orientation of the brain fibre tracts was proven with the gold standard histology analysis. We present the results of post-processing of Mueller polarimetric images of fixed human brain sections using a combination of classical computer vision and machine learning algorithms, for the automated brain fibre tracking in the white matter tracts. Manually labelled polarimetric data was used to train a convolutional neural network to identify white matter. Within the identified white matter, surface fibre tracts could be visualized. We expect that Mueller polarimetric imaging modality combined with our ML algorithms for fibre tracking will visualize the directions of fibre tracts in imaging plane during tumor surgery, thus, allowing a neurosurgeon to orient himself, to spare essential fibre tracts and to make surgery more complete and safe.

Proceedings Article | 7 December 2021 Paper

Retardance map of brain white matter: a potential game changer for the intra-operative navigation during brain tumor surgery

Omar Roriguez-Núñez, Philippe Schucht, Hee Ryung Lee, Mohammed Hachem Mezouar, Ekkehard Hewer, Andreas Raabe, Michael Murek, Irena Zubak, Johannes Goldberg, Enikö Kövari, Angelo Pierangelo, Tatiana Novikova

Proceedings Volume 11919, 119190Y (2021) https://doi.org/10.1117/12.2614598

KEYWORDS: Brain, Tumors, Tissue optics, Polarimetry, Neuroimaging, Brain mapping, Tissues, Surgery, Polarization, Visualization

Read Abstract +

Proceedings Article | 5 March 2021 Presentation

Wide-field imaging of brain white matter fiber tracts with Mueller polarimetry in backscattering configuration

Tatiana Novikova, Philippe Schucht, Hee Ryung Lee, Mohammed Hachem Mezouar, Ekkehard Hewer, Andreas Raabe, Michael Murek, Irena Zubak, Johannes Goldberg, Enikö Kövari, Angelo Pierangelo

Proceedings Volume 11641, 1164105 (2021) https://doi.org/10.1117/12.2588957

Read Abstract +

Proceedings Article | 5 March 2021 Presentation

Wide-field imaging of brain white matter fiber tracts with Mueller polarimetry in backscattering configuration

Philippe Schucht, Hee Ryung Lee, Mohammed Hachem Mezouar, Ekkehard Hewer, Andreas Raabe, Michael Murek, Irena Zubak, Johannes Goldberg, Enikö Kövari, Angelo Pierangelo, Tatiana Novikova

Proceedings Volume 11646, 1164605 (2021) https://doi.org/10.1117/12.2577872

KEYWORDS: Brain, Neuroimaging, Tumors, Tissue optics, Polarimetry, Backscatter, Visualization, Anisotropy, Surgery, Imaging systems

Read Abstract +

Showing 5 of 12 publications

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Keywords/Phrases

Search In:

Publication Years