Mr. Michel Fournier Profile

Michel Fournier

at Univ de Sherbrooke

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Proceedings Article | 29 August 2017 Paper

Studies of photosensitizers from the phthalocyanine family in the perspective of two-photon photodynamic therapy

Michel Fournier

Proceedings Volume 10313, 1031338 (2017) https://doi.org/10.1117/12.2283912

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Photodynamic therapy (PDT) of cancer is a treatment with strengths and weaknesses. Amongst the latter is the need for the presence of oxygen for the photodynamic effect to occur. It is a known fact that singlet oxygen, generated from the first triplet excited state (T1) of the photosensitizer, is responsible for the lethal photodynamic effect [1, 2, 3, 4]. The problem lies in the lack of oxygen in the core of a tumor. It seems that the excited triplet state energy of the photosensitizers currently in use in PDT lies below the threshold of a lethal anoxic chemical reaction.

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