Mr. Mikhail A. Sizov Profile

Mikhail A. Sizov

at E.L. Berezov City Clinical Hospital No. 7

SPIE Involvement:

Author

Publications (1)

This will count as one of your downloads.

You will have access to both the presentation and article (if available).

DOWNLOAD NOW

This content is available for download via your institution's subscription. To access this item, please sign in to your personal account.

Email or Username Forgot your username?

Password Forgot your password?

Show

Keep me signed in

No SPIE account? Create an account

Proceedings Article | 7 March 2022 Presentation + Paper

Intestinal optical coherence tomography (angiography) imaging: a comparison between animal models and humans

Elena Kiseleva, Maxim Ryabkov, Mikhail Baleev, Mikhail Sizov, Alexander Moiseev, Grigory Gelikonov, Peter Peretyagin, Alexander Vorobiev, Natalia Gladkova

Proceedings Volume 11949, 1194908 (2022) https://doi.org/10.1117/12.2608405

KEYWORDS: Optical coherence tomography, Intestine, Tissues, Visualization, Blood vessels, Angiography, Ischemia, Surgery

Read Abstract +

Transserosal optical coherence tomography (OCT) with angiography modality (OCTA) provides real-time label-free visualization of the intestinal structure and blood vessels networks with a spatial resolution about 10-15 µm. This method is a perspective for intraoperative use in abdominal surgery, for example, for determining the depth of ischemic damage to the gut. The paper devoted to analysis the quality of OCT/OCTA data obtained from small intestine of 4 subjects - rat, rabbit, minipigs and humans. The subjects have different thickness of intestinal wall and blood circulation conditions. It was shown, that the intestine of small laboratory animals (rats and rabbits) is convenient for studying with OCT/OCTA: it can be easily stabilized by moving the intestine loop outside the body, which, together with a rigidly fixed probe, minimizes the number of possible motion artifacts. Therefore, OCT/OCTA criteria of structural changes in the intestinal wall and microcirculation disorders during ischemia, important for clinical applications, were established on these objects. Large animals (minipigs) and human proved to be a troublesome subjects for obtaining high-quality OCT/OCTA data: powerful peristaltic movements, pronounced pulse wave and the inability to take the object out of the body in order to exclude the influence of respiratory and other types of the body movements led to a sharp increase in the amount of OCT/OCTA images with artifacts (up to 39% in humans). However, in patients and minipigs the microstructure of intestinal layers was more informative than in small animals due to increased thickness. Therefore, it allowed visualize tissues in more detail: in particular, verify peritoneum edema and intramuscular fluid buildup. The study was performed under support of RFBR grant No.19-75-10096.

My Library

You currently do not have any folders to save your paper to! Create a new folder below.

Folder Name

Folder Description

View contact details

UPDATE YOUR PROFILE

Is this your profile? Update it now.

Sign into your SPIE.org account

Don’t have a profile and want one?

Create an account on SPIE.org

Access to the requested content is limited to institutions that have purchased or subscribe to SPIE eBooks. You are receiving this notice because your organization may not have SPIE eBooks access.*

*Shibboleth/Open Athens users─please sign in to access your institution's subscriptions.

To obtain this item, you may purchase the complete book in print or electronic format on SPIE.org.

ORGANIZATIONAL
Sign in with credentials provided by your organization.

Organizational Username

Organizational Password

Show/Hide Password

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members:

Non-members: ADD TO CART

Keywords/Phrases

Search In:

Publication Years