In the present work the effectiveness of antioxidants quercetine (a pure chemical) and Gratiola officinalis extract, which is obtained by a new method of extraction from plant material, is investigated on the model of photodynamic haemolysis that is a rather convenient method to monitor the rate of cell membranes oxidative destruction. The effect of these antioxidants on the rate of photodynamic haemolysis is considered as a measure of membranoprotective efficiency.
On the model of photodynamic haemolysis, the membranoprotective properties of a plant origin antioxidant, GratiolaofficinalisL. extract, have been studied based on its ability to inhibit photodamage of sensitized erythrocyte membranes. The effect of different concentrations of the antioxidant on the photodynamic hemolysis has been studied; and the influence of incubation time on the membranoprotective properties of GratiolaofficinalisL. extract has also been revealed.