Dr. Osman O. Ahsen
SPIE Involvement:
Area of Expertise:
Optical coherence tomography , Intravascular imaging , Esophageal cancer and dysplasia , Endoscopic imaging , Fluorescence imaging , Nonlinear microscopy
Profile Summary

I have done my graduate research in the research group that pioneered the development of Optical Coherence Tomography (OCT) imaging technology. During my tenure at the MIT, I have made contributions to several OCT and fluorescence imaging technologies including swept source-OCT, Optical Coherence Microscopy and Nonlinear Imaging Microscopy. These imaging devices were developed in a highly collaborative setting involving clinical collaborators at the VA Boston Healthcare System and Beth Israel Deaconess Medical Center, as well as our industrial partners at the Thorlabs, Inc and Praevium Research, Inc. I got the opportunity to work on throughout the various stages of medical device development pipeline, which involved development of basic technology, demonstrating its safety and effectiveness in preclinical settings, obtaining regulatory approvals for in human testing and finally conducting large-scale human studies to assess clinical utility. Recently, I joined Dr. Guillermo J. Tearney’s group at Wellman Center at the MGH, and have shifted my focus to intravascular imaging. In Dr. Tearney’s group I am working on developing novel multi-modal intravascular imaging technologies aimed to improve clinical management of coronary artery disease, by combining an array of technologies such as OCT, near-infrared fluorescence and near-infrared autofluorescence (NIRAF) imaging, and endothelial shear stress measurement methods.
Publications (9)

Proceedings Article | 7 March 2022 Presentation
Evangelia Gavgiotaki, Radhika Poduval, David Otuya, Alissa Cirio, Shoumik Lodh, Tyler Rihm, Rachel Shore, Peter Choy, Sarah Silva, Alexander Krall, Paola Leon Alarcon, Patricia Grahmann, Osman Ahsen, Guillermo Tearney
Proceedings Volume PC11937, PC1193701 (2022) https://doi.org/10.1117/12.2607309
KEYWORDS: Monochromatic aberrations, Micro optics, Optical coherence tomography, Endoscopy, 3D image processing, Stereoscopy, Lenses, Image quality standards, Zemax, Optics manufacturing

Proceedings Article | 7 March 2022 Presentation
Proceedings Volume PC11936, PC1193602 (2022) https://doi.org/10.1117/12.2605295
KEYWORDS: Optical coherence tomography, Luminescence, Inflammation, Imaging systems, In vivo imaging, Visualization, Tomography, Target detection, Fluorescence spectroscopy, Coherence (optics)

Proceedings Article | 5 March 2021 Presentation
Proceedings Volume 11621, 116210O (2021) https://doi.org/10.1117/12.2577841
KEYWORDS: Optical coherence tomography, Luminescence, Imaging systems, Tissues, Process control, Near infrared, Visualization, Standards development, Lens design, Control systems

Proceedings Article | 5 March 2021 Presentation
Proceedings Volume 11630, 116300P (2021) https://doi.org/10.1117/12.2582536

Proceedings Article | 7 March 2019 Presentation
Kensuke Nishimiya, Osman Ahsen, Biwei Yin, Zhonglie Piao, Jiheun Ryu, Hany Osman, Gargi Sharma, Hui Min Leung, Chia-Pin Liang, Joseph Gardecki, Guillermo Tearney
Proceedings Volume 10855, 1085502 (2019) https://doi.org/10.1117/12.2506264
KEYWORDS: Arteries, Visualization, Image segmentation, Scanning electron microscopy, Image resolution, Imaging technologies, Coherence (optics), Tomography, 3D image processing, Image processing

Showing 5 of 9 publications
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