Dr. D. Patrick O'Neal Profile

Dr. D. Patrick O'Neal

Chief Technology Officer at Wavegate Corp

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Author

Publications (16)

Proceedings Article | 4 March 2016 Presentation + Paper

Assessment of multi-wavelength pulse photometry for non-invasive dose estimation of circulating drugs and nanoparticles

Pratik Adhikari, Wakako Eklund, Eric Sherer, D. Patrick O'Neal

Proceedings Volume 9715, 97150O (2016) https://doi.org/10.1117/12.2213455

KEYWORDS: Photoplethysmography, Photometry, Nanoparticles, Densitometry, Optical sensing, Blood, Tissue optics, Feedback control, Point-of-care devices, Sensing systems, Optical instrument design, Absorbance, Gold, Medicine, Scattering, Oximetry

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Proceedings Article | 9 March 2015 Paper

Non-invasive in vivo monitoring of circulating amphotericin b using multi-wavelength photoplethysmography

Pratik Adhikari, Wakako Eklund, Patrick O'Neal

Proceedings Volume 9332, 93320H (2015) https://doi.org/10.1117/12.2083798

KEYWORDS: Blood, In vivo imaging, Nanoparticles, Absorption, Signal attenuation, Therapeutic agents, Oxygen, LabVIEW, Signal detection, Photoplethysmography

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Proceedings Article | 28 March 2014 Paper

The use of real-time optical feedback to improve outcomes

Isidro Magaña, Pratik Adhikari, Raghuvara Yendluri, Glenn Goodrich, Jon Schwartz, D. O'Neal

Proceedings Volume 8955, 89550R (2014) https://doi.org/10.1117/12.2040066

KEYWORDS: Tumors, Data modeling, Gold, Nanoparticles, Therapeutics, Blood pressure, Particles, Biological research, Clinical trials, Nanorods

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Proceedings Article | 28 February 2014 Paper

Multi-wavelength pulse plethysmography for real-time drug delivery monitoring

Pratik Adhikari, Isidro Magaña, Patrick O'Neal

Proceedings Volume 8951, 89510P (2014) https://doi.org/10.1117/12.2040064

KEYWORDS: Nanoparticles, Signal attenuation, Blood, Absorption, Absorbance, Particles, Gold, Therapeutics, Photometry, Tumors

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Proceedings Article | 11 February 2011 Paper

An optical device employing multiwavelength photoplethysmography for non-invasive in-vivo monitoring of optically active nanoparticles

Gregory Michalak, Pratik Adhikari, Jon Schwartz, Glenn Goodrich, D. Patrick O'Neal

Proceedings Volume 7906, 790604 (2011) https://doi.org/10.1117/12.875089

KEYWORDS: Nanoparticles, Blood, Photometry, Particles, Absorbance, Signal attenuation, Tumors, Spectrophotometry, Nanorods, Photoplethysmography

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Proceedings Article | 16 February 2009 Paper

Circulation time estimates of optically active nanoparticles using a pulse photometer

Gregory Michalak, Jon Schwartz, D. Patrick O'Neal

Proceedings Volume 7188, 71880M (2009) https://doi.org/10.1117/12.809667

KEYWORDS: Nanoparticles, Photometry, Blood, Particles, Spectrophotometry, Absorbance, Tumors, Sensors, Prototyping, Absorption

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Proceedings Article | 9 February 2007 Paper

Characterization of laser-induced thermal response of nanoshells for cancer treatment using magnetic-resonance temperature imaging

Andrew Elliott, R. Stafford, Jon Schwartz, James Wang, Anil Shetty, Chris Bourgoyne, D. O'Neal, John Hazle

Proceedings Volume 6440, 64400G (2007) https://doi.org/10.1117/12.700957

KEYWORDS: Tumors, Finite element methods, Temperature metrology, In vivo imaging, Cancer, Laser therapeutics, Absorption, Gold, Tissues, Near infrared

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Proceedings Article | 28 February 2006 Paper

Magnetic resonance temperature imaging of nanoshell photo-thermal therapy

D. Patrick O'Neal, R. Jason Stafford, John Hazle

Proceedings Volume 6095, 609505 (2006) https://doi.org/10.1117/12.647184

KEYWORDS: Tumors, Tissues, Magnetic resonance imaging, Gold, In vivo imaging, Particles, Nanoparticles, Silica, Laser therapeutics, Magnetism

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Proceedings Article | 25 April 2005 Paper

Laser tissue soldering with near-infrared absorbing nanoparticles

Andre Gobin, D. O'Neal, Naomi Halas, Rebekah Drezek, Jennifer West

Proceedings Volume 5686, (2005) https://doi.org/10.1117/12.590614

KEYWORDS: Gold, Tissues, Laser welding, Laser tissue interaction, Absorption, Nanoparticles, Near infrared, Tissue optics, Wound healing, Silica

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Proceedings Article | 8 April 2005 Paper

Photothermal cancer therapy using intravenously injected near-infrared-absorbing nanoparticles

D. O'Neal, Leon Hirsch, Naomi Halas, J. Payne, Jennifer West

Proceedings Volume 5689, (2005) https://doi.org/10.1117/12.590819

KEYWORDS: Tumors, Tissues, Gold, Nanoparticles, Laser therapeutics, Temperature metrology, Near infrared, Blood, Cancer, Infrared radiation

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Proceedings Article | 23 May 2002 Paper

Feasibility of an online fluorescence-based optical sensor for oxygen monitoring in cell-culture media

D. O'Neal, Michael Meledeo, Michael Pishko, Gerard Cote

Proceedings Volume 4624, (2002) https://doi.org/10.1117/12.468311

KEYWORDS: Oxygen, Sensors, Ruthenium, Optical sensors, Light emitting diodes, Proteins, Luminescence, Linear filtering, Modulation, CCD image sensors

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Proceedings Article | 23 May 2002 Paper

Investigation of pH and temperature effects on FRET systems for glucose sensing

Michael Meledeo, Bennett Ibey, D. O'Neal, Michael Pishko, Gerard Cote

Proceedings Volume 4624, (2002) https://doi.org/10.1117/12.468327

KEYWORDS: Glucose, Fluorescence resonance energy transfer, Sensing systems, Luminescence, Sensors, Molecules, Blood, Polymers, Proteins, Temperature metrology

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Proceedings Article | 13 June 2001 Paper

Implantable biosensors: analysis of fluorescent light propagation through skin

D. O'Neal, Michael McShane, Michael Pishko, Gerard Cote

Proceedings Volume 4263, (2001) https://doi.org/10.1117/12.429340

KEYWORDS: Glucose, Skin, Sensors, Luminescence, Molecules, Tissues, Biosensors, Biological research, Polymers, Fluorescence resonance energy transfer

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Proceedings Article | 31 May 2000 Paper

Progress toward implantable fluorescence-based sensors for monitoring glucose levels in interstitial fluid

Michael McShane, Dennis O'Neal, Ryan Russell, Michael Pishko, Gerard Cote

Proceedings Volume 3923, (2000) https://doi.org/10.1117/12.387127

KEYWORDS: Glucose, Sensors, Luminescence, Skin, Optical spheres, In vivo imaging, Calibration, In vitro testing, Signal to noise ratio, Chemistry

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Proceedings Article | 8 May 2000 Paper

Surface-enhanced Raman spectroscopy for the near real-time diagnosis of brain trauma in rats

D. O'Neal, Massoud Motamedi, Jefferson Chen, Gerard Cote

Proceedings Volume 3918, (2000) https://doi.org/10.1117/12.384939

KEYWORDS: Surface enhanced Raman spectroscopy, Brain, Ischemia, Silver, Raman spectroscopy, Statistical analysis, Injuries, Neuroimaging, Head, Microfluidics

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Proceedings Article | 9 April 1999 Paper

Surface-enhanced Raman spectroscopy for the in-vitro and ex-vivo detection of excitatory amino acids

D. O'Neal, Massoud Motamedi, Jefferson Chen, Gerard Cote

Proceedings Volume 3608, (1999) https://doi.org/10.1117/12.345404

KEYWORDS: Surface enhanced Raman spectroscopy, Brain, Injuries, Head, In vitro testing, Silver, Raman spectroscopy, Microfluidics, Ischemia, Nervous system

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Showing 5 of 16 publications

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