Adaptive optics full-filed OCT (FFOCT) with a transmissive liquid crystal spatial light modulator
(LCSLM) as wavefront corrector is used without strict plane conjugation for low order aberrations
corrections. We validated experimentally that FFOCT resolution is independent of aberrations and
only reduce the signal level. A signal based sensorless algorithm was thus applied for wavefront
distortion compensation. Image quality improvements by the wavefront sensorless control of the
LCSLM were evaluated on in vitro samples. By replacing the FFOCT sample arm objective with an
artificial eye used to train ophthalmologists, adaptive optics retinal imaging was achieved. In vivo
experiments using a liquid lens to correct focus and astigmatism are underway.
We describe a simple and compact full-field optical coherence tomography (FFOCT) setup coupled to a transmissive liquid crystal spatial light modulator (LCSLM) to induce or correct aberrations. To reduce the system complexity, strict pupil conjugation was abandoned because low-order aberrations are often dominant. We experimentally confirmed a recent theoretical and experimental demonstration that the image resolution was almost insensitive to aberrations that mostly induce a reduction of the signal level. As a consequence, an image-based algorithm was applied for the optimization process by using the FFOCT image intensity as the metric. Aberration corrections were demonstrated with both an USAF resolution target and biological samples for LCSLM-induced and sample-induced wavefront distortions.