Dr. Puxiang Lai
Assistant Professor at Hong Kong Polytechnic Univ
SPIE Involvement:
Author
Area of Expertise:
biomedical optics , biomedical ultrasound , optical focusing in tissue , ultrasound-modulated optical tomography , acousto-optic imaging , optic holograhy
Websites:
Profile Summary

Puxiang Lai had his bachelor’s degree in Biomedical Engineering in 2002 from Tsinghua University, Beijing, China, and his master’s degree in Acoustics in 2005 from the Chinese Academy of Sciences. Between 2005 and 2010, he studied at Boston University for his PhD degree, under the supervision of Prof. Ronald A. Roy and Prof. Todd W. Murray in the Department of Mechanical Engineering. His research at Boston University was concentrated on the development of new biomedical sensing modalities using sound and light, with the aim to improve the spatial resolution of optical sensing in biological tissue. In 2010, Puxiang Lai joined Dr. Lihong Wang’s Optical Imaging Laboratory as a postdoc research associate at the Department of Biomedical Engineering, Washington University in St. Louis. Besides acousto-optic sensing (also called ultrasound-modulated optical tomography) and photoacoustic imaging, he has also expanded his interests to optical focusing inside (not through) thick turbid media with the guidance of focused ultrasound (including ultrasound modulation and ultrasound sensing). Thus far, his projects on this topic have majorly included (1) the development of a reflection-mode time-reversed ultrasonically encoded (TRUE) optical focusing system; (2) the first demonstration of TRUE optical focusing in thick biological tissue; (3) the direct visualization and dynamic control of TRUE optical focusing in turbid media; (4) the demonstration of localized fluorescence excitation and imaging in highly scattering media with TRUE light; (5) the development of a millisecond-order TRUE optical focusing system, which achieves the first optical focusing inside dynamic (moving) turbid media and living biological tissue; (6) the development of ultrasonically-encoded wavefront shaping (SEWS) for optical focusing; and (7) the development of nonlinear photoacoustic wavefront shaping (PAWS) for optical focusing.
Publications (19)

SPIE Journal Paper | March 6, 2014
JBO Vol. 19 Issue 03
KEYWORDS: Scattering, Tissue optics, Temperature metrology, Water, Biomedical optics, Particles, Refractive index, Solids, Scatter measurement, Reflectometry

PROCEEDINGS ARTICLE | March 3, 2014
Proc. SPIE. 8943, Photons Plus Ultrasound: Imaging and Sensing 2014
KEYWORDS: Phase conjugation, Biomedical optics, Visualization, Ultrasonography, Luminescence, Wavefronts, Ultrasonics, Ocean optics, Tissue optics, Analog electronics

PROCEEDINGS ARTICLE | March 3, 2014
Proc. SPIE. 8943, Photons Plus Ultrasound: Imaging and Sensing 2014
KEYWORDS: Biomedical optics, Scattering media, Light scattering, Wavefronts, Spatial light modulators, Transducers, Signal processing, Photoacoustic spectroscopy, Tissue optics, Feedback signals

PROCEEDINGS ARTICLE | March 3, 2014
Proc. SPIE. 8943, Photons Plus Ultrasound: Imaging and Sensing 2014
KEYWORDS: Point spread functions, Modulation, Scattering, Ultrasonography, Photons, Light scattering, Ultrasonics, Transducers, Tissue optics, Acoustics

PROCEEDINGS ARTICLE | March 3, 2014
Proc. SPIE. 8943, Photons Plus Ultrasound: Imaging and Sensing 2014
KEYWORDS: Phase conjugation, Holography, Speckle, Scattering media, Ultrasonography, Crystals, Light scattering, Speckle pattern, Tissue optics, Signal detection

PROCEEDINGS ARTICLE | March 3, 2014
Proc. SPIE. 8943, Photons Plus Ultrasound: Imaging and Sensing 2014
KEYWORDS: Scattering, Scattering media, Ultrasonography, Light scattering, Laser scattering, Wavefronts, Adaptive optics, Spatial light modulators, Diffusers, Tissue optics

Showing 5 of 19 publications
SIGN IN TO:
  • View contact details

UPDATE YOUR PROFILE
Is this your profile? Update it now.
Don’t have a profile and want one?

Back to Top