Prof. Rinaldo Cubeddu Profile

Prof. Rinaldo Cubeddu

Professor Emeritus at Politecnico di Milano

SPIE Involvement:

Author

Publications (141)

Proceedings Article | 9 August 2023 Paper

Evaluation of neoadjuvant chemotherapy-induced changes in contralateral healthy breast tissue through diffuse optical spectroscopy

Nikhitha Mule, Giulia Maffeis, Carolina Santangelo, Rinaldo Cubeddu, Antonio Pifferi, Pietro Panizza, Paola Taroni

Proceedings Volume 12628, 1262808 (2023) https://doi.org/10.1117/12.2670661

KEYWORDS: Tissues, Breast, Diffuse optical spectroscopy, Chemotherapy, Breast cancer, Tumors, Tissue optics, Spectral response, Optical imaging, Mammography

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Proceedings Article | 9 August 2023 Paper

Initial examples of the SOLUS multimodal potential

G. Maffeis, A. Pifferi, A. Dalla Mora, L. Di Sieno, R. Cubeddu, A. Tosi, E. Conca, A. Giudice, A. Ruggeri, S. Tisa, A. Flocke, B. Rosinski, J.-M. Dinten, M. Perriollat, C. Fraschini, J. Lavaud, S. Arridge, G. Di Sciacca, A. Farina, P. Panizza, E. Venturini, P. Gordebeke, P. Taroni

Proceedings Volume 12628, 1262807 (2023) https://doi.org/10.1117/12.2670430

KEYWORDS: Radio optics, Machine learning, Data processing, Absorption, Ultrasonography, Multimodal imaging, Elastography, Doppler tomography, Diffuse optical tomography, Critical dimension metrology

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Proceedings Article | 7 March 2023 Presentation + Paper

Breast lesion classification based on absorption and composition parameters: a look at SOLUS first outcomes

G. Maffeis, A. Pifferi, A. Dalla Mora, L. Di Sieno, R. Cubeddu, A. Tosi, E. Conca, A. Giudice, A. Ruggeri, S. Tisa, A. Flocke, B. Rosinski, J.-M Dinten, M. Perriollat, C. Fraschini, J. Lavaud, S. Arridge, G. Di Sciacca, A. Farina, P. Panizza, E. Venturini, P. Gordebeke, Paola Taroni

Proceedings Volume 12376, 123760K (2023) https://doi.org/10.1117/12.2648945

KEYWORDS: Breast, Absorption, Machine learning, Image segmentation, Diffuse optical tomography, Diffuse optical imaging, Data analysis, Breast cancer, Ultrasound transducers

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Proceedings Article | 7 March 2023 Presentation + Paper

Monitoring neoadjuvant chemotherapy through time domain diffuse optical spectroscopy: preliminary clinical results

Nikhitha Mule, Giulia Maffeis, Carolina Santangelo, Rinaldo Cubeddu, Antonio Pifferi, Pietro Panizza, Paola Taroni

Proceedings Volume 12376, 123760L (2023) https://doi.org/10.1117/12.2648865

KEYWORDS: Breast, Tumors, Collagen, Tissues, Chemotherapy, Breast cancer, Optical sensing, Imaging spectroscopy, Diffuse optical spectroscopy, Diffuse optical imaging

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SPIE Journal Paper | 2 February 2022 Open Access

Reproducibility of identical solid phantoms

Fangzhou Zhao, Pietro Levoni, Lorenzo Frabasile, Hong Qi, Michele Lacerenza, Pranav Lanka, Alessandro Torricelli, Antonio Pifferi, Rinaldo Cubeddu, Lorenzo Spinelli

JBO, Vol. 27, Issue 07, 074713, (February 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.7.074713

KEYWORDS: Scattering, Silicon, Absorption, Solids, Optical properties, Picosecond phenomena, Near infrared spectroscopy, Epoxies, Diffuse optical imaging, Visible radiation

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Proceedings Article | 9 December 2021 Paper

Filament 3D printing technology for diffuse optics applications: advantages and drawbacks

Caterina Amendola, Michele Lacerenza, Ileana Pirovano, Davide Contini, Lorenzo Spinelli, Rinaldo Cubeddu, Alessandro Torricelli, Rebecca Re

Proceedings Volume 11920, 1192020 (2021) https://doi.org/10.1117/12.2615431

KEYWORDS: 3D printing, Mass attenuation coefficient, Printing, 3D metrology, Near infrared spectroscopy, Diffuse optical imaging, 3D acquisition, Spectroscopy, Photons, Optical properties

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Proceedings Article | 9 December 2021 Paper

Optical mammography in the time domain up to 1060 nm: from tests on healthy women to initial data for monitoring neoadjuvant chemotherapy

Giulia Maffeis, Edoardo Ferocino, Alberto Dalla Mora, Rinaldo Cubeddu, Antonio Pifferi, Carolina Santangelo, Pietro Panizza, Paola Taroni

Proceedings Volume 11920, 119200O (2021) https://doi.org/10.1117/12.2615236

KEYWORDS: Breast, Tumors, Collagen, Therapeutics, In vivo imaging, Oxygen, Optical testing, Mammography, Clinical trials, Signal processing

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Proceedings Article | 9 December 2021 Paper

Discrimination between healthy and glaucomatous subjects with TD-fNIRS

R. Re, D. Messenio, G. Marano, L. Spinelli, I. Pirovano, D. Contini, R. Colombo, P. Boracchi, E. Biganzoli, R. Cubeddu, A. Torricelli

Proceedings Volume 11920, 119200G (2021) https://doi.org/10.1117/12.2615222

KEYWORDS: Visualization, Eye, Statistical analysis, Brain, Hemodynamics, Eye models, Absorption, Visual optics, Scattering, Medical devices

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Proceedings Article | 7 December 2021 Paper

Rehabilitation monitoring after bed rest in elderly: TD-NIRS and sEMG preliminary study

I. Pirovano, A. Laurini, A. Tomba, A. Scano, R. Re, A. Caserta, L. Spinelli, D. Contini, R. Cubeddu, L. Panella, A. Torricelli

Proceedings Volume 11919, 1191921 (2021) https://doi.org/10.1117/12.2615017

KEYWORDS: Tissues, Electromyography, Hemodynamics, Near infrared spectroscopy, Ultrasonography, Surgery, Scattering, Oxygen, Head, Data analysis

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Proceedings Article | 5 March 2021 Presentation + Paper

Broadband optical spectroscopy of the human adipose and muscle tissues: an in-vivo pilot study

Sri Rama Pranav Kumar Lanka, A. Segala, Andrea Farina, Paola Taroni, A. Valerio, E. Nisoli, Rinaldo Cubeddu, Antonio Pifferi

Proceedings Volume 11639, 116390I (2021) https://doi.org/10.1117/12.2578276

KEYWORDS: Tissues, In vivo imaging, Optical spectroscopy, Optical properties, Diffuse optical spectroscopy, Tissue optics, Spectroscopy, Oximetry, Near infrared

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Proceedings Article | 5 March 2021 Presentation + Paper

High-throughput multi-wavelength time-resolved optical mammograph: importance of in vivo performance assessment

Giulia Maffeis, Edoardo Ferocino, Alberto Dalla Mora, Rinaldo Cubeddu, Antonio Pifferi, Paola Taroni

Proceedings Volume 11639, 1163908 (2021) https://doi.org/10.1117/12.2577516

KEYWORDS: In vivo imaging, Collagen, Stray light, Silicon photomultipliers, Optical properties, New and emerging technologies, Infrared radiation, Clinical trials, Breast, Absorption

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Proceedings Article | 2 March 2020 Presentation + Paper

Key features in the optical properties of tissue during and after radiofrequency ablation

Francis Kalloor Joseph, Pranav Lanka, Hindrik Kruit, Sanathana Konugolu Venkata Sekar, Andrea Farina, Rinaldo Cubeddu, Srirang Manohar, Antonio Pifferi

Proceedings Volume 11216, 112160H (2020) https://doi.org/10.1117/12.2546042

KEYWORDS: Tissue optics, Optical properties, Radiofrequency ablation, Tissues, Absorption, Scattering, Liver, Electrodes, Biomedical optics, Radio optics

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Proceedings Article | 22 July 2019 Paper

Solid heterogeneous phantoms for multimodal ultrasound and diffuse optical imaging: an outcome of the SOLUS project for standardization

Laura Di Sieno, Rinaldo Cubeddu, Hélène Sportouche, David Savéry, Sanathana Konugolu Venkata Sekar, Bogdan Rosinski, Andrea Farina, Edoardo Ferocino, Pranav Lanka, Paola Taroni, Antonio Pifferi, Alberto Dalla Mora

Proceedings Volume 11075, 1107516 (2019) https://doi.org/10.1117/12.2526645

KEYWORDS: Ultrasonography, Optical properties, Diffuse optical imaging, Silicon, Imaging systems, Solids, Multimodal imaging, Tissues, Absorption, Calibration

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Proceedings Article | 11 July 2019 Paper

TD-fNIRS for diagnosing glaucoma: a clinical pilot study

R. Re, D. Messenio, L. Spinelli, I. Pirovano, D. Contini, R. Colombo, R. Cubeddu, A. Torricelli

Proceedings Volume 11074, 110741K (2019) https://doi.org/10.1117/12.2526961

KEYWORDS: Visualization, Visual cortex, Hemodynamics, Signal detection, Eye, Optic nerve, Brain, Optical coherence tomography, Visual optics, Optical discs

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Proceedings Article | 11 July 2019 Paper

Monitoring radiofrequency ablation of biological tissue using broadband time-resolved diffuse optical spectroscopy

Pranav Lanka, K. Francis, Hindrik Kruit, Sanathana Konugolu Venkata Sekar, Andrea Farina, Rinaldo Cubeddu, Srirang Manohar, Antonio Pifferi

Proceedings Volume 11074, 110742M (2019) https://doi.org/10.1117/12.2526964

KEYWORDS: Radiofrequency ablation, Tissues, Tissue optics, Diffuse optical spectroscopy, Breast, Optical properties, Liver, Laser ablation, Biomedical optics, Absorption, Scattering

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Proceedings Article | 11 July 2019 Paper

Spatially-enhanced time-domain NIRS for determination of optical properties in layered structures

Lin Yang, Pranav Lanka, Heidrun Wabnitz, Rinaldo Cubeddu, Thomas Gladytz, Sanathana Konugolu Venkata Sekar, Dirk Grosenick, Antonio Pifferi, Rainer Macdonald

Proceedings Volume 11074, 110740A (2019) https://doi.org/10.1117/12.2527032

KEYWORDS: Absorption, Near infrared spectroscopy, Optical properties, Scattering, Monte Carlo methods, Tissue optics, Tissues, Brain

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Proceedings Article | 17 May 2018 Presentation + Paper

Multidistance time domain diffuse optical spectroscopy in the assessment of abdominal fat heterogeneity

P. Lanka, A. Farina , S. Konugolu Venkata Sekar, C. Guadagno , L. Spinelli , P. Taroni, R. Cubeddu , E. Nisoli, A. Pifferi

Proceedings Volume 10685, 1068513 (2018) https://doi.org/10.1117/12.2307350

KEYWORDS: Absorption, Scattering, Tissues, Diffuse optical spectroscopy, Data modeling, Tissue optics, In vivo imaging, Optical properties, Abdomen, Medicine

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Proceedings Article | 28 July 2017 Paper

Attractive new technologies for 7-wavelength time domain optical mammography

Edoardo Ferocino, Edoardo Martinenghi, Alberto Dalla Mora, Antonio Pifferi, Rinaldo Cubeddu, Paola Taroni

Proceedings Volume 10412, 1041202 (2017) https://doi.org/10.1117/12.2286058

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Proceedings Article | 28 July 2017 Paper

In vivo depth heterogeneity of the abdomen assessed by broadband time-domain diffuse optical spectroscopy

A. Farina, S. Konugolu Venkata Sekar, C. Guadagno, L. Spinelli, P. Lanka, P. Taroni, R. Cubeddu, E. Nisoli, A. Pifferi

Proceedings Volume 10412, 104120M (2017) https://doi.org/10.1117/12.2286067

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SPIE Journal Paper | 11 July 2016 Open Access

Review of optical breast imaging and spectroscopy

Dirk Grosenick, Herbert Rinneberg, Rinaldo Cubeddu, Paola Taroni

JBO, Vol. 21, Issue 09, 091311, (July 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.9.091311

KEYWORDS: Breast, Tissue optics, Tumors, Tissues, Mammography, Scattering, Absorption, Breast imaging, Imaging spectroscopy, Spectroscopy

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SPIE Journal Paper | 28 July 2015 Open Access

Mechanically switchable solid inhomogeneous phantom for performance tests in diffuse imaging and spectroscopy

Antonio Pifferi, Alessandro Torricelli, Rinaldo Cubeddu, Giovanna Quarto, Rebecca Re, Sanathana K. V. Sekar, Lorenzo Spinelli, Andrea Farina, Fabrizio Martelli, Heidrun Wabnitz

JBO, Vol. 20, Issue 12, 121304, (July 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.12.121304

KEYWORDS: Absorption, Solids, Picosecond phenomena, Scattering, Transmittance, Imaging spectroscopy, Sensors, Optical fibers, Optical properties, Reflectivity

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Proceedings Article | 16 July 2015 Paper

Design and construction of a solid switchable phantom for diffuse optical imaging

Antonio Pifferi, Fabrizio Martelli, Lorenzo Spinelli, Andrea Farina, Rebecca Re, Giovanna Quarto, Sanathana Konugolu Venkata Sekar, Alessandro Torricelli, Rinaldo Cubeddu, Mikhail Mazurenka, Rainer Macdonald, Heidrun Wabnitz

Proceedings Volume 9538, 95380Q (2015) https://doi.org/10.1117/12.2183657

KEYWORDS: Picosecond phenomena, Solids, Diffuse optical imaging, Absorption, Optical fibers, Reflectivity, Transmittance, Scattering, Optical properties, Brain

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Proceedings Article | 16 July 2015 Paper

Collagen content as a risk factor in breast cancer? A pilot clinical study

Antonio Pifferi, Giovanna Quarto, Francesca Abbate, Nicola Balestreri, Simona Menna, Enrico Cassano, Rinaldo Cubeddu, Paola Taroni

Proceedings Volume 9538, 953813 (2015) https://doi.org/10.1117/12.2183618

KEYWORDS: Collagen, Cancer, Breast, Breast cancer, Tissue optics, Mammography, Diagnostics, Diffuse optical imaging, Picosecond phenomena, Oncology

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Proceedings Article | 16 July 2015 Paper

Optical discrimination between malignant and benign breast lesions

Giovanna Quarto, Antonio Pifferi, Rinaldo Cubeddu, Francesca Ieva, Anna Maria Paganoni, Francesca Abbate, Enrico Cassano, Paola Taroni

Proceedings Volume 9538, 953814 (2015) https://doi.org/10.1117/12.2183616

KEYWORDS: Breast, Tissues, Tissue optics, Absorption, Collagen, Tumor growth modeling, Mammography, Photons, Mie scattering, Scattering

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Proceedings Article | 16 July 2015 Paper

Optical study on the dependence of breast tissue composition and structure on subject anamnesis

Paola Taroni, Giovanna Quarto, Antonio Pifferi, Francesca Abbate, Nicola Balestreri, Simona Menna, Enrico Cassano, Rinaldo Cubeddu

Proceedings Volume 9538, 953812 (2015) https://doi.org/10.1117/12.2183427

KEYWORDS: Breast, Tissue optics, Scattering, Tissues, Absorption, Collagen, Breast cancer, Brain-machine interfaces, Mammography, Oncology

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Proceedings Article | 22 June 2015 Open Access

Time domain diffuse optical spectroscopy: in-vivo quantification of collagen in breast tissue

Paola Taroni, Antonio Pifferi, Giovanna Quarto, Andrea Farina, Francesca Ieva, Anna Maria Paganoni, Francesca Abbate, Enrico Cassano, Rinaldo Cubeddu

Proceedings Volume 9529, 952910 (2015) https://doi.org/10.1117/12.2187775

KEYWORDS: Collagen, Breast, Tissue optics, Tissues, Scattering, Absorption, Breast cancer, Diffuse optical spectroscopy, Geometrical optics, In vivo imaging

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Proceedings Article | 6 March 2015 Paper

Solid switchable phantom for diffuse optical imaging

Antonio Pifferi, Alessandro Torricelli, Rinaldo Cubeddu, Giovanna Quarto, Rebecca Re, Sanathana Konugolu Venkata Sekar, Lorenzo Spinelli, Andrea Farina, Fabrizio Martelli, Heidrun Wabnitz

Proceedings Volume 9325, 932505 (2015) https://doi.org/10.1117/12.2084789

KEYWORDS: Absorption, Solids, Transmittance, Scattering, Optical properties, Imaging systems, Picosecond phenomena, Diffuse optical imaging, Optical spheres, Electroluminescent displays

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SPIE Journal Paper | 14 August 2014 Open Access

Performance assessment of time-domain optical brain imagers, part 1: basic instrumental performance protocol

Heidrun Wabnitz, Dieter Taubert, Mikhail Mazurenka, Oliver Steinkellner, Alexander Jelzow, Rainer Macdonald, Daniel Milej, Piotr Sawosz, Michał Kacprzak, Adam Liebert, Robert Cooper, Jeremy Hebden, Antonio Pifferi, Andrea Farina, Ilaria Bargigia, Davide Contini, Matteo Caffini, Lucia Zucchelli, Lorenzo Spinelli, Rinaldo Cubeddu, Alessandro Torricelli

JBO, Vol. 19, Issue 08, 086010, (August 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.8.086010

KEYWORDS: Neuroimaging, Brain, Imaging systems, Sensors, Tissue optics, Biomedical optics, In vivo imaging, Transmittance, Absorption, Solids

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SPIE Journal Paper | 14 August 2014 Open Access

Performance assessment of time-domain optical brain imagers, part 2: nEUROPt protocol

Heidrun Wabnitz, Alexander Jelzow, Mikhail Mazurenka, Oliver Steinkellner, Rainer Macdonald, Daniel Milej, Norbert Żołek, Michał Kacprzak, Piotr Sawosz, Roman Maniewski, Adam Liebert, Salavat Magazov, Jeremy Hebden, Fabrizio Martelli, Paola Di Ninni, Giovanni Zaccanti, Alessandro Torricelli, Davide Contini, Rebecca Re, Lucia Zucchelli, Lorenzo Spinelli, Rinaldo Cubeddu, Antonio Pifferi

JBO, Vol. 19, Issue 08, 086012, (August 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.8.086012

KEYWORDS: Absorption, Brain, Neuroimaging, Imaging systems, Optical properties, Sensors, Data analysis, Liquids, Biomedical optics, Spatial resolution

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SPIE Journal Paper | 14 July 2014 Open Access

Phantoms for diffuse optical imaging based on totally absorbing objects, part 2: experimental implementation

Fabrizio Martelli, Paola Di Ninni, Giovanni Zaccanti, Davide Contini, Lorenzo Spinelli, Alessandro Torricelli, Rinaldo Cubeddu, Heidrun Wabnitz, Mikhail Mazurenka, Rainer Macdonald, Angelo Sassaroli, Antonio Pifferi

JBO, Vol. 19, Issue 07, 076011, (July 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.7.076011

KEYWORDS: Absorption, Photons, Scattering, Optical properties, Liquids, Diffuse optical imaging, Solids, Reflectivity, Sensors, Monte Carlo methods

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Proceedings Article | 7 March 2014 Paper

Hyperspectral (fluorescence lifetime) imaging based on a UV-VIS enhanced supercontinuum source using high-order mode propagation

Stefano Taccheo, Raffaella Mercatelli, Silvia Soria, Cosimo D'Andrea, Kay Schuster, Andreas Bassi, Rinaldo Cubeddu, Jens Kobelke, Klaus Mörl, Giancarlo Righini, Franco Quercioli

Proceedings Volume 8972, 89720M (2014) https://doi.org/10.1117/12.2039001

KEYWORDS: Luminescence, Ultraviolet radiation, Visible radiation, Fluorescence lifetime imaging, Fluorescence resonance energy transfer, Sapphire lasers, Biomedical optics, Hyperspectral imaging, Picosecond phenomena, Supercontinuum sources

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SPIE Journal Paper | 26 June 2013 Open Access

Optical identification of subjects at high risk for developing breast cancer

Paola Taroni, Giovanna Quarto, Antonio Pifferi, Francesca Ieva, Anna Maria Paganoni, Francesca Abbate, Nicola Balestreri, Simona Menna, Enrico Cassano, Rinaldo Cubeddu

JBO, Vol. 18, Issue 06, 060507, (June 2013) https://doi.org/10.1117/12.10.1117/1.JBO.18.6.060507

KEYWORDS: Breast, Collagen, Tissue optics, Breast cancer, Scattering, Mammography, Tissues, X-ray optics, X-rays, Breast imaging

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Proceedings Article | 24 June 2013 Paper

Multi-laboratory investigation of the optical properties of the human head

A. Farina, A. Pifferi, A. Torricelli, I. Bargigia, L. Spinelli, R. Cubeddu, F. Foschum, M. Jäger, E. Simon, O. Fugger, A. Kienle, F. Martelli, P. Di Ninni, G. Zaccanti, A. Jelzow, E. Kirilina, H. Wabnitz, J. Heiskala, M. Schweiger, S. Arridge

Proceedings Volume 8804, 880408 (2013) https://doi.org/10.1117/12.2032577

KEYWORDS: Head, Optical properties, Scattering, Absorption, Data modeling, Sensors, Skull, Signal detection, Data analysis

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Proceedings Article | 24 June 2013 Paper

Functional near-infrared spectroscopy at small source-detector distance by means of high dynamic-range fast-gated SPAD acquisitions: first in-vivo measurements

L. Di Sieno, D. Contini, A. Dalla Mora, A. Torricelli, L. Spinelli, R. Cubeddu, A. Tosi, G. Boso, A. Pifferi

Proceedings Volume 8804, 880402 (2013) https://doi.org/10.1117/12.2032492

KEYWORDS: Photons, Optical fibers, Near infrared spectroscopy, Sensors, Signal to noise ratio, In vivo imaging, Picosecond phenomena, Tissue optics, Avalanche photodiodes, Biomedical optics

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Proceedings Article | 14 June 2013 Paper

Optical identification of subjects at high risk for developing breast cancer

Paola Taroni, Giovanna Quarto, Antonio Pifferi, lorenzo Spinelli, Alessandro Torricelli, Francesca Ieva, Anna Maria Paganoni, Francesca Abbate, Nicola Balestreri, Simona Menna, Enrico Cassano, Rinaldo Cubeddu

Proceedings Volume 8799, 87990O (2013) https://doi.org/10.1117/12.2032456

KEYWORDS: Breast, Collagen, Scattering, Tissue optics, Breast cancer, Tissues, Mammography, Radio optics, Mie scattering, Data modeling

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Proceedings Article | 14 June 2013 Paper

Comparison of organic phantom recipes and characterization by time-resolved diffuse optical spectroscopy

G. Quarto, A. Pifferi, I. Bargigia, A. Farina, R. Cubeddu, P. Taroni

Proceedings Volume 8799, 879905 (2013) https://doi.org/10.1117/12.2032489

KEYWORDS: Scattering, Tissue optics, Tissues, Absorption, Diffuse optical spectroscopy, Optical properties, Breast, Transmittance, Mie scattering, Time resolved spectroscopy

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Proceedings Article | 14 June 2013 Paper

In-vivo optical spectroscopy in the time-domain beyond 1100 nm

I. Bargigia, A. Tosi, A. Bahgat Shehata, A. Della Frera, A. Farina, A. Bassi, P. Taroni, A. Dalla Mora, F. Zappa, R. Cubeddu, A. Pifferi

Proceedings Volume 8799, 879902 (2013) https://doi.org/10.1117/12.2032521

KEYWORDS: Absorption, In vivo imaging, Breast, Scattering, Optical spectroscopy, Tissues, Sensors, Monte Carlo methods, Collagen, Biomedical optics

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Proceedings Article | 26 March 2013 Paper

In vivo imaging of zebrafish from embryo to adult stage with optical projection tomography

Andrea Bassi, Luca Fieramonti, Cosimo D'Andrea, Gianluca Valentini, Rinaldo Cubeddu, Sandro De Silvestri, Giulio Cerullo, Efrem Foglia, Franco Cotelli

Proceedings Volume 8593, 85930A (2013) https://doi.org/10.1117/12.2004340

KEYWORDS: Tomography, Optical tomography, Projection systems, In vivo imaging, Light scattering, Scattering, Photons, Reconstruction algorithms, 3D image processing, Organisms

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Proceedings Article | 25 March 2013 Paper

Multi-channel time-resolved functional near infrared spectroscopy system

D. Contini, R. Re, M. Turola, L. Spinelli, G. Romano, R. Cubeddu, A. Torricelli

Proceedings Volume 8578, 857832 (2013) https://doi.org/10.1117/12.2004967

KEYWORDS: Brain, Absorption, Functional near infrared spectroscopy, Hemodynamics, Sensors, Tissues, Tissue optics, In vivo imaging, Signal to noise ratio, Control systems

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Proceedings Article | 14 March 2013 Paper

Memory effect in gated single-photon avalanche diodes: a limiting noise contribution similar to afterpulsing

D. Contini, A. Dalla Mora, L. Di Sieno, R. Cubeddu, A. Tosi, G. Boso, A. Pifferi

Proceedings Volume 8619, 86191L (2013) https://doi.org/10.1117/12.2005013

KEYWORDS: Sensors, Photons, Avalanche photodiodes, Pulsed laser operation, Silicon, Optical testing, Solids, Spectroscopy, Signal detection, Picosecond phenomena

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Proceedings Article | 28 February 2013 Paper

Performance assessment of time-domain optical brain imagers: a multi-laboratory study

Heidrun Wabnitz, Alexander Jelzow, Mikhail Mazurenka, Oliver Steinkellner, Rainer Macdonald, Antonio Pifferi, Alessandro Torricelli, Davide Contini, Lucia Zucchelli, Lorenzo Spinelli, Rinaldo Cubeddu, Daniel Milej, Norbert Zolek, Michal Kacprzak, Piotr Sawosz, Adam Liebert, Salavat Magazov, Jeremy Hebden, Fabrizio Martelli, Paola Di Ninni, Giovanni Zaccanti

Proceedings Volume 8583, 85830L (2013) https://doi.org/10.1117/12.2002438

KEYWORDS: Absorption, Data analysis, Brain, Neuroimaging, Imaging systems, Spatial resolution, Liquids, Optical properties, Sensors, Brain imaging

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SPIE Journal Paper | 4 May 2012 Open Access

Load-dependent brain activation assessed by time-domain functional near-infrared spectroscopy during a working memory task with graded levels of difficulty

Erika Molteni, Giuseppe Baselli, Sergio Cerutti, Anna Maria Bianchi, Davide Contini, Matteo Caffini, Rinaldo Cubeddu, Alessandro Torricelli, Lorenzo Spinelli

JBO, Vol. 17, Issue 5, 056005, (May 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.5.056005

KEYWORDS: Brain activation, Data modeling, Cognitive modeling, Statistical analysis, Near infrared spectroscopy, Brain, Hemodynamics, Brain mapping, Functional magnetic resonance imaging, Control systems

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Proceedings Article | 15 February 2012 Paper

Neuronal rat cell imaging using a new UV-extended supercontinuum source

Stefano Taccheo, Silvia Soria, Cosimo D'Andrea, Kay Schuster, Andrea Bassi, Rinaldo Cubeddu, Jens Kobelke, Klaus Mörl, Gualtiero Nunzi Conti, Giancarlo Righini, Franco Quercioli

Proceedings Volume 8247, 82470D (2012) https://doi.org/10.1117/12.910381

KEYWORDS: Ultraviolet radiation, Visible radiation, Confocal microscopy, Supercontinuum sources, Microscopes, Sapphire lasers, Glia, Laser scanners, Biomedical optics, Laser sources

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Proceedings Article | 15 June 2011 Paper

Assessment of cortical response during motor task in adults by a multimodality approach based on fNIRS-EEG, fMRI-EEG, and TMS

Alessandro Torricelli, Davide Contini, Matteo Caffini, Lucia Zucchelli, Rinaldo Cubeddu, Lorenzo Spinelli, Erika Molteni, Anna Maria Bianchi, Giuseppe Baselli, Sergio Cerutti, Elisa Visani, Isabella Gilioli, Davide Rossi Sebastiano, Elena Schiaffi, Ferruccio Panzica, Silvana Franceschetti

Proceedings Volume 8088, 808802 (2011) https://doi.org/10.1117/12.889809

KEYWORDS: Functional magnetic resonance imaging, Electroencephalography, Brain mapping, Fiber optics, Functional imaging, Near infrared spectroscopy, Neuroimaging, Light sources, Magnetic resonance imaging, Electrodes

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Proceedings Article | 15 June 2011 Paper

Breast density assessment by means of time domain optical mammography at 635-1060 nm

Paola Taroni, Antonio Pifferi, Giovanna Quarto, Lorenzo Spinelli, Alessandro Torricelli, Rinaldo Cubeddu, Francesca Abbate, Anna Villa, Nicola Balestreri, Simona Menna, Enrico Cassano

Proceedings Volume 8088, 80881E (2011) https://doi.org/10.1117/12.889373

KEYWORDS: Breast, Collagen, Tissue optics, Tissues, Scattering, Mammography, Absorption, Breast cancer, Radio optics, Diagnostics

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Proceedings Article | 15 June 2011 Paper

Anatomical brain atlas for NIRS measurements of brain activation

Matteo Caffini, Lucia Zucchelli, Davide Contini, Rinaldo Cubeddu, Lorenzo Spinelli, David Boas, Alessandro Torricelli

Proceedings Volume 8088, 808809 (2011) https://doi.org/10.1117/12.889679

KEYWORDS: Visualization, Sensors, Near infrared spectroscopy, Brain, Head, Brain activation, Absorption, Monte Carlo methods, Neuroimaging, Photon transport

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Proceedings Article | 15 June 2011 Paper

Time-domain diffuse optical spectroscopy beyond 1100 nm: initial feasibility study

Antonio Pifferi, Ilaria Bargigia, Paola Taroni, Andrea Farina, Rinaldo Cubeddu

Proceedings Volume 8088, 808817 (2011) https://doi.org/10.1117/12.889735

KEYWORDS: Absorption, Collagen, Breast, Diffuse optical spectroscopy, In vivo imaging, Sensors, Diamond, Supercontinuum sources, Tissues, Prisms

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Proceedings Article | 1 March 2011 Paper

First in vivo spectral characterization of breast up to 1300 nm

P. Taroni, I. Bargigia, A. Farina, R. Cubeddu, A. Pifferi

Proceedings Volume 7896, 78962L (2011) https://doi.org/10.1117/12.874778

KEYWORDS: Absorption, Collagen, Breast, Tissues, In vivo imaging, Tissue optics, Signal attenuation, Reflectivity, Sensors, Optical spectroscopy

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Proceedings Article | 18 February 2011 Paper

In vivo swine myocardial tissue characterization and monitoring during open chest surgery by time-resolved diffuse near-infrared spectroscopy

Lorenzo Spinelli, Davide Contini, Andrea Farina, Alessandro Torricelli, Antonio Pifferi, Rinaldo Cubeddu, Luca Ascari, Luca Potì, Maria Giovanna Trivella, Antonio L'Abbate, Stefano Puzzuoli

Proceedings Volume 7883, 78833D (2011) https://doi.org/10.1117/12.874697

KEYWORDS: Heart, Tissue optics, Near infrared spectroscopy, Absorption, Chest, Scattering, Surgery, Tissues, In vivo imaging, Light scattering

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Proceedings Article | 17 February 2011 Paper

Time-domain diffuse optical spectroscopy up to 1700 nm using an InGaAs/InP single-photon avalanche diode

Ilaria Bargigia, Alberto Tosi, Andrea Farina, Andrea Bassi, Paola Taroni, Andrea Bahgat Shehata, Adriano Della Frera, Alberto Dalla Mora, Franco Zappa, Rinaldo Cubeddu, Antonio Pifferi

Proceedings Volume 7895, 78950C (2011) https://doi.org/10.1117/12.874947

KEYWORDS: Absorption, Collagen, Diffuse optical spectroscopy, Avalanche photodiodes, Scattering, Tissues, Laser scattering, Spectral resolution, Temporal resolution, Picosecond phenomena

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Proceedings Article | 17 February 2011 Paper

Assessment of basic instrumental performance of time-domain optical brain imagers

Heidrun Wabnitz, Antonio Pifferi, Alessandro Torricelli, Dieter Taubert, Mikhail Mazurenka, Oliver Steinkellner, Alexander Jelzow, Andrea Farina, Ilaria Bargigia, Davide Contini, Matteo Caffini, Lucia Zucchelli, Lorenzo Spinelli, Piotr Sawosz, Adam Liebert, Rainer Macdonald, Rinaldo Cubeddu

Proceedings Volume 7896, 789602 (2011) https://doi.org/10.1117/12.874654

KEYWORDS: Neuroimaging, Brain, Imaging systems, Sensors, Tissue optics, Transmittance, Electronics, Photomultipliers, Brain imaging, Picosecond phenomena

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Proceedings Article | 11 February 2011 Paper

Generation of UV and blue light by using off-axis pumping for fluorescence lifetime spectroscopy

S. Taccheo, C. D'Andrea, A. Bassi, R. Cubeddu, K. Schuster, J. Kobelke, K. Morl, S. Soria-Huguet, G. Nunzio Conti, G. Righini

Proceedings Volume 7925, 792507 (2011) https://doi.org/10.1117/12.872945

KEYWORDS: Luminescence, Spectroscopy, Fluorescence spectroscopy, Visible radiation, Ultraviolet radiation, Sapphire lasers, Biomedical optics, Dispersion, Light wave propagation, Bandpass filters

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SPIE Journal Paper | 1 November 2010 Open Access

Noninvasive assessment of breast cancer risk using time-resolved diffuse optical spectroscopy

Paola Taroni, Antonio Pifferi, Giovanna Quarto, Lorenzo Spinelli, Alessandro Torricelli, Francesca Abbate, Anna Villa, Nicola Balestreri, Simona Menna, Enrico Cassano, Rinaldo Cubeddu

JBO, Vol. 15, Issue 06, 060501, (November 2010) https://doi.org/10.1117/12.10.1117/1.3506043

KEYWORDS: Breast, Collagen, Tissue optics, Breast cancer, Tissues, Scattering, Transmittance, Diffuse optical spectroscopy, Radio optics, Mammography

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Proceedings Article | 29 April 2010 Paper

Functional diffuse reflectance spectroscopy at small source-detector distances based on fast-gated single-photon avalanche diodes

Davide Contini, Antonio Pifferi, Lorenzo Spinelli, Alessandro Torricelli, Rinaldo Cubeddu, Fabrizio Martelli, Giovanni Zaccanti, Alberto Dalla Mora, Alberto Tosi, Franco Zappa, Sergio Cova

Proceedings Volume 7681, 768102 (2010) https://doi.org/10.1117/12.852557

KEYWORDS: Diffuse reflectance spectroscopy, Picosecond phenomena, Avalanche photodiodes, Biomedical optics, Photodetectors, Brain, Spatial resolution, Reflectivity, Absorption, Sensors

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Proceedings Article | 24 February 2010 Paper

Fast-gated single-photon detectors boost dynamic range in NIR spectroscopy

A. Tosi, A. Dalla Mora, F. Zappa, S. Cova, D. Contini, A. Pifferi, L. Spinelli, A. Torricelli, R. Cubeddu

Proceedings Volume 7556, 75560G (2010) https://doi.org/10.1117/12.840910

KEYWORDS: Photodetectors, Picosecond phenomena, Sensors, Signal detection, Near infrared spectroscopy, Near infrared, Silicon, Single photon detectors, Time metrology, Biomedical optics

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SPIE Journal Paper | 1 September 2009 Open Access

Diffuse optical spectroscopy of breast tissue extended to 1100 nm

Paola Taroni, Andrea Bassi, Daniela Comelli, Andrea Farina, Rinaldo Cubeddu, Antonio Pifferi

JBO, Vol. 14, Issue 05, 054030, (September 2009) https://doi.org/10.1117/12.10.1117/1.3251051

KEYWORDS: Breast, Absorption, Collagen, Tissue optics, Tissues, Scattering, In vivo imaging, Diffuse optical spectroscopy, Diagnostics, Spectroscopy

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