This paper discusses the ongoing development of a compact, unattended low-power radiation detection system designed
for autonomous operation in regions with limited or no supporting infrastructure. This application motivates our focus on
two of the more challenging system development problems: (1) the development of compact, low-power electronics for
gamma-ray spectrometers and neutron detectors, and (2) analysis algorithms capable of distinguishing special nuclear
material from benign sources in the opaque signatures of
mid-resolution spectrometers. We discuss our development
efforts on these fronts and present results based on implementation in a proof-of-principle system composed of two 5-cm
× 10-cm × 41-cm NaI(Tl) crystals and eight 40-cm <sup>3</sup>He tubes.