Since 1992, military medicine has considered the relevance, sustainability, and promise of telemedicine in the context of its mission and obligations for service members at home and in war zones. The US Army telemedicine program covers 22 time zones and generates over 5000 tele-consults per month for over 20 medical specialties. More recently the advances in mobile computing and increased adoption of the Smartphone with evolving capabilities for imaging and body-worn sensor integration has emerged in the field called mobile health, or mHealth. This presentation highlights the first 10 years of the U.S. Army mHealth program and includes how similar technologies have translated to wide-scale civilian health care implementation, including a relevant project for Veterans at the University of Pittsburgh. Examples include the successful US Army “mCare” program developed to augment soldier rehabilitation management with USbased geographically dispersed providers that utilizes secure mobile messaging and the soldier’s own cell phone. Additional research interests will describe the use of smartphones on the battlefield enabling capture of operational medical data to improve casualty evacuation and outcome. A DoD-funded traumatic brain injury research project developed for Veterans at the University of Pittsburgh includes a mobile health application that demonstrates the effectiveness of communicating with patients through their personal mobile devices with care managers. Preliminary data for all the projects presented are encouraging for adoption and utilization of a mobile telemedicine platform to meet the complex needs of casualties injured or recovering from a broad range of injuries in unique geographic settings.