Dr. Ruth M. Woodward Profile

Dr. Ruth M. Woodward

Technology Advisor

SPIE Involvement:

Author | Instructor

Proceedings Article | 19 May 2005 Paper

Terahertz technology in global homeland security

Ruth Woodward

Proceedings Volume 5781, (2005) https://doi.org/10.1117/12.606392

KEYWORDS: Terahertz radiation, Homeland security, Terahertz technology, Sensors, Molecules, Target detection, Molecular interactions, Electromagnetism, Explosives, Liquids

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Proceedings Article | 19 May 2005 Paper

Terahertz and millimetre wave technology in port and harbour security

Ruth Woodward, Roger Appleby

Proceedings Volume 5780, (2005) https://doi.org/10.1117/12.605493

KEYWORDS: Terahertz radiation, Imaging systems, Sensors, Signal attenuation, Target detection, Terahertz technology, Imaging spectroscopy, Electromagnetism, Reflectivity, Extremely high frequency

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Proceedings Article | 1 April 2005 Paper

An analytical model of skin: comparison with experimental results in vivo

Ruth Woodward

Proceedings Volume 5692, (2005) https://doi.org/10.1117/12.597340

KEYWORDS: Skin, Terahertz radiation, Water, Tissues, Molecules, Absorption, Picosecond phenomena, In vivo imaging, Refractive index, Dielectrics

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Terahertz pulsed imaging is a non-invasive, non-ionizing imaging technique, using electromagnetic radiation defined in the frequency range 0.1 THz to 10 THz. Using reflection imaging systems with a frequency range 0.1 THz to 4 THz a far field diffraction limited lateral resolution of 3 mm to 110 microns is attainable. A three layer analytical model has been developed to simulate the hydration properties of skin in reflection. Earlier in vivo hydration measurements of the volar forearm and palm of the hand (thenar) are compared to this model. The time-domain analysis technique “time post pulse” (TPP) used to differentiate between diseased and normal tissue in a study of basal cell carcinoma was applied to the data. An increase in the value of TPP is observed with occlusion in the viable epidermis. This is attributed to an increase in the flux of water across the epidermis or dermis with increased stratum corneum hydration. This is verified by the literature. The change is observed in less than six minutes occlusion, making terahertz technology one of the most sensitive techniques for monitoring skin hydration levels. The contrast observed at the stratum corneum-viable epidermis interface is similar to that seen between diseased and normal tissue. Although water provides a good marker for studying diseased tissue, comparing results from DNA and protein analysis, it is not yet possible to conclude whether the contrast observed in basal cell carcinoma is due to increased water within the diseased tissue, a change in the vibrational modes of water with other functional groups, or a change in the vibrational modes of the functional groups alone. Further studies are required to determine whether terahertz technology is capable of differentiating between different histological subtypes in a collective system such as skin at a macroscopic level. The three layer analytical model provides a useful adjunct for identifying the source of contrast observed in the top surface of skin.

Proceedings Article | 29 December 2004 Paper

Terahertz technology in biological and chemical sensing for defence

Ruth Woodward

Proceedings Volume 5617, (2004) https://doi.org/10.1117/12.569427

KEYWORDS: Sensors, Terahertz radiation, Terahertz technology, Defense and security, Environmental sensing, Molecules, Atmospheric sensing, Biological and chemical sensing, Electromagnetism, Homeland security

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Proceedings Article | 1 July 2004 Paper

Tissue classification using terahertz pulsed imaging

Ruth Woodward, Anthony Fitzgerald, Vincent Wallace

Proceedings Volume 5318, (2004) https://doi.org/10.1117/12.527477

KEYWORDS: Tissues, Terahertz radiation, Skin, Diagnostics, Statistical analysis, Cancer, Skin cancer, Colorectal cancer, Tissue optics, Tumors

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Proceedings Article | 12 September 2003 Paper

Terahertz pulsed imaging of cancers

Vincent Wallace, Ruth Woodward, Anthony Fitzgerald, E. Pickwell, Richard Pye, Donald Arnone

Proceedings Volume 4949, (2003) https://doi.org/10.1117/12.500121

KEYWORDS: Terahertz radiation, Tissues, Skin, Cancer, Skin cancer, Tissue optics, Colorectal cancer, Absorption, Semiconductor lasers, Laser applications

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Proceedings Article | 4 June 2002 Paper

Terahertz pulse imaging in reflection geometry of skin tissue using time-domain analysis techniques

Ruth Woodward, Vincent Wallace, Bryan Cole, Richard Pye, Donald Arnone, Edmund Linfield, Michael Pepper

Proceedings Volume 4625, (2002) https://doi.org/10.1117/12.469785

KEYWORDS: Tissues, Inflammation, Terahertz radiation, Skin, Tissue optics, Solids, In vitro testing, Skin cancer, Statistical analysis, Molecules

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Proceedings Article | 29 May 2001 Paper

Terahertz imaging and spectroscopy of human skin in vivo

Bryan Cole, Ruth Woodward, David Crawley, Vincent Wallace, Donald Arnone, Michael Pepper

Proceedings Volume 4276, (2001) https://doi.org/10.1117/12.428010

KEYWORDS: Terahertz radiation, Skin, In vivo imaging, Water, Tissue optics, Tissues, Picosecond phenomena, Imaging systems, Quartz, Interfaces

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Showing 5 of 8 publications

Conference Committee Involvement (5)

Advanced Biomedical and Clinical Diagnostic Systems VI

20 January 2008 | San Jose, California, United States

Advanced Biomedical and Clinical Diagnostic Systems V

21 January 2007 | San Jose, California, United States

Optics and Photonics in Global Homeland Security II

19 April 2006 | Orlando (Kissimmee), Florida, United States

Advanced Biomedical and Clinical Diagnostic Systems IV

22 January 2006 | San Jose, California, United States

Advanced Biomedical and Clinical Diagnostic Systems III

23 January 2005 | San Jose, CA, United States

Course Instructor

SC718: Terahertz Technology in Homeland Security and Defense

This course will introduce the basic techniques in terahertz technology for imaging and spectroscopy in homeland security and defense. The course reviews the progress of the technology in the security and defense arena, including recent developments in sources and detectors. The focus will be specifically on the application of the technology for improvised explosive device (IED) detection and chemical and biological sensing. The methods required for the successful imaging and spectroscopy of target materials will be discussed, in addition to the appropriate implementation of standards for identifying the viability of terahertz technology in this arena. The student will receive an understanding of the challenges and potential of terahertz technology in homeland security and defense.

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SC697: Terahertz Techniques in Medical Imaging and Spectroscopy

This course will introduce the basic techniques in terahertz technology for medical imaging and spectroscopy. The course reviews the progress of the technology in the medical and pharmaceutical industry, and discusses the current advantages and disadvantages of the technology compared to other optical imaging and spectroscopy techniques. The methods required for the successful imaging and spectroscopy of biological samples will be discussed, in addition to good working practices. The student will receive an understanding of the challenges and potential of terahertz technology for medical imaging and spectroscopy.

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