Ryan C. Denomme
Founder/CEO at Nicoya Lifesciences Inc
SPIE Involvement:
Author
Area of Expertise:
Fabrication , Nanomaterials , Biosensors , Plasmonics , Optics and Photonics , Process Development
Profile Summary

Currently I am developing a label-free biosensor that uses the optical properties of metal nanoparticles to detect binding of target analytes. I am working on miniaturizing the device for portable applications, while increasing sensitivity and improving detection limits. This is being achieved through optimization of nanoparticle properties using detailed simulations and through improving hardware, sensing algorithms, and detection protocols.
Publications (4)

SPIE Journal Paper | 26 July 2013
Ryan Denomme, Krishna Iyer, Michael Kreder, Brendan Smith, Patricia Nieva
JM3, Vol. 12, Issue 03, 031106, (July 2013) https://doi.org/10.1117/12.10.1117/1.JMM.12.3.031106
KEYWORDS: Photoresist materials, Nanoparticles, Silver, Lithography, Sensors, Metals, Nanolithography, Photomasks, Optical lithography, Semiconducting wafers

Proceedings Article | 23 February 2012 Paper
R. Denomme, Z. Young, L. Brock, P. Nieva, M. Vijayan
Proceedings Volume 8269, 82692G (2012) https://doi.org/10.1117/12.908888
KEYWORDS: Nanoparticles, Sensors, Proteins, Biosensors, Prisms, Refractive index, Gold, Absorbance, Surface plasmons, Metals

Proceedings Article | 14 February 2012 Paper
Sasan Asiaei, Ryan Denomme, Chelsea Marr, Patricia Nieva, Mathilakath Vijayan
Proceedings Volume 8251, 825107 (2012) https://doi.org/10.1117/12.907370
KEYWORDS: Self-assembled monolayers, Nanoparticles, Gold, Molecules, Spectroscopy, Surface plasmons, Chemisorption, Mathematical modeling, Diffusion, Molecular self-assembly

Proceedings Article | 8 February 2011 Paper
R. Denomme, K. Iyer, M. Kreder, B. Smith, P. Nieva
Proceedings Volume 7927, 79270B (2011) https://doi.org/10.1117/12.875427
KEYWORDS: Nanoparticles, Metals, Photoresist materials, Sensors, Silver, Optical lithography, Lithography, Photomasks, Glasses, Surface plasmons

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