<i>In-Check</i> is STMicroelectronics proprietary platform for molecular diagnostics. In-Check lays its foundations on the
monolithic integration of microelectronics and micromachining technology MEMS, with microfluidic and optical
features, bio-chemical surface functionalization and molecular biology. It comprises a core lab-on-chip device, control
and reading instrumentation, a complete suite of software modules, and application protocols. Leveraging on such
capabilities, <i>In-Check </i>enables fast, highly sensitive and specific, multi-analytical capability of nucleic acid analysis. The
platform provides a unique combination of nucleic acid amplification, by polymerase-chain-reaction and target
identification and typing by DNA microarray. These integrated biological functionalities together with top quality
standard and process control are key features for a platform to be accepted by the highly demanding modern medical
diagnostic. This paper describes recent developments of <i>In-Check </i>and some core biological characterizations.
Organic Thin Film Transistors (OTFTs) have been fabricated, in a standard bottom gate configuration, with Langmuir-Schafer (LS) or cast thin films of regioregular poly[1,4-(2,5-dioctyloxyphenylene)-2,5-thiophene], synthesized via an organometallic protocol, as active layers. The transistors electrical characterization has evidenced that LS based devices exhibit better performance level than cast film ones. Appealing perspectives for newly substituted conjugated polymers in OTFT sensing devices are discussed.