LASERIX is a high-power laser facility leading to High-repetition-rate XUV laser pumped by Titanium:Sapphire laser.
The aim of this laser facility is to offer Soft XRLs in the 30-7 nm range and auxiliary IR beam that could also be used to
produce synchronized XUV sources. This experimental configuration highly enhances the scientific opportunities of the
facility, giving thus the opportunity to realize both X-ray laser experiments and more generally pump/probe experiments,
mixing IR and XUV sources. In this contribution, the main results concerning both the development of XUV sources(X-Ray
lasers and HHG sources) and their use for applications are presented.
Samples of plasmid DNA were irradiated with pulsed 18.9 nm radiation originating from a Mo X-ray laser (XRL)
pumped in GRIP configuration at the LASERIX facility. Up to 21 000 pulses were delivered with a repetition rate of 10
Hz and average pulse energy of 200 nJ. Radiosensitization by two different platinum compounds (platinum terpyridine
chloride (PtTC) and platinum nanoparticles) were investigated. SSB and DSB yields were measured using agarose gel
electrophoresis. The occurrence of single and double strand breaks not present in controls having undergone the same
treatment except for the XRL irradiation can be seen as a clear effect of the XRL irradiation. This confirms the role of
direct effects in DNA damages as previously seen with low energy ions and electrons (1) (2). In addition we demonstrate
a DNA breaks enhancement in the presence of platinum. No difference of enhancement was seen between these two
The LASERIX facility provides coherent and short soft x-ray beams for scientific applications. The beams are generated through high intensity laser interaction with matter using two different schemes, plasma based soft x-ray lasers, and high order laser harmonic generation. We describe in this communication the present status
of the facility. The LASERIX beamtime has been recently opened to external users. We present two typical experiments performed in that context with the facility. The first one is dedicated to the fundamental study of the plasma based soft x-ray laser, whereas the second uses the existing beam to study irradiation induced
dammage in DNA samples. We present also the development performed on the soft x-ray laser source to improve its stability and high repetition rate operation.