Prof. Serge R. Mordon Profile

Prof. Serge R. Mordon

Research Director at INSERM

SPIE Involvement:

Conference Program Committee | Conference Chair | Author

Publications (67)

Proceedings Article | 8 February 2017

Intraoperative photodynamic treatment for high-grade gliomas

C. Dupont, N. Reyns, P. Deleporte, S. Mordon, M. Vermandel

Proc. SPIE. 10047, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXVI

KEYWORDS: Light sources, Laser therapeutics, Photodynamic therapy, Tumors, Tissues, Surgery, Luminescence, Control systems, Diffusers, Light sources and illumination, Medical devices, System on a chip, Radiation oncology, Liquids, Brain, Clinical trials

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Proceedings Article | 8 February 2017

Photodynamic therapy in neurosurgery: a proof of concept of treatment planning system

C. Dupont, N. Reyns, S. Mordon, M. Vermandel

Proc. SPIE. 10047, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXVI

KEYWORDS: Optical fibers, Modeling, Light sources, Phototherapy, Laser therapeutics, Photodynamic therapy, Tumors, Tissues, Surgery, Image segmentation, Image registration, Diffusers, Biological research, Brain, Clinical trials

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Proceedings Article | 6 February 2017

Light emitting fabric for photodynamic treatment of actinic keratosis

E. Thecua, C. Vicentini, A-S. Vignion, F. Lecomte, P. Deleporte, L. Mortier, R.-M. Szeimies, S. Mordon

Proc. SPIE. 10037, Photonics in Dermatology and Plastic Surgery

KEYWORDS: Optical fibers, Laser sources, Light sources, Light emitting diodes, Phototherapy, Laser therapeutics, Photodynamic therapy, Sun, Dermatology, Skin, Photography, Laser optics, Light

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SPIE Journal Paper | 22 May 2015

Comparison of three light doses in the photodynamic treatment of actinic keratosis using mathematical modeling

Anne-Sophie Vignion-Dewalle, Nacim Betrouni, Jean-Baptiste Tylcz, Maximilien Vermandel, Laurent Mortier, Serge Mordon

JBO Vol. 20 Issue 05

KEYWORDS: Photodynamic therapy, Skin, Oxygen, Absorption, Statistical modeling, Molecules, Mathematical modeling, Optical properties, Cancer, Tissues

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Proceedings Article | 10 March 2015

Interstitial photodynamic therapy and glioblastoma: light fractionation study on a preclinical model: preliminary results

Henri-Arthur Leroy, Maximilien Vermandel, Marie-Charlotte Tétard, Jean-Paul Lejeune, Serge Mordon, Nicolas Reyns

Proc. SPIE. 9305, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics II

KEYWORDS: Phototherapy, Photodynamic therapy, Tumors, Tissues, Magnetic resonance imaging, Diffusion, Oxygen, Picosecond phenomena, Tissue optics, Brain

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SPIE Journal Paper | 8 March 2012

Development of a new illumination procedure for photodynamic therapy of the abdominal cavity

Laurie Guyon, Jean Claude Lesage, Nacim Betrouni, Serge Mordon

JBO Vol. 17 Issue 03

KEYWORDS: Photodynamic therapy, Luminescence, Magnetic resonance imaging, Liver, Tumors, Laparoscopy, In vivo imaging, Tumor growth modeling, Intestine, Oxygen

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Proceedings Article | 2 March 2010

Real-time magnetic resonance imaging texture characterization of necrosis during laser interstitital thermotherapy procedures

N. Betrouni, R. Lopes, P. Colin, S. Mordon

Proc. SPIE. 7548, Photonic Therapeutics and Diagnostics VI

KEYWORDS: Laser therapeutics, Liver, Tumors, Tissues, Magnetic resonance imaging, Fiber lasers, Image analysis, Fractal analysis, In vivo imaging, Heat therapy

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Proceedings Article | 13 July 2009

Comparison of aminolevulinic acid and hexylester aminolevulinate induced protoporphyrin IX fluorescence for the detection of ovarian carcinoma metastases: an experimental study

Manuel Ascencio, Claudia Regis, Serge Mordon, Pierre Collinet

Proc. SPIE. 7380, Photodynamic Therapy: Back to the Future

KEYWORDS: Tumor growth modeling, Tumors, Visualization, Tissues, Microscopy, Luminescence, Fluorescence spectroscopy, Biopsy, Ovarian cancer, Laparoscopy

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Proceedings Article | 12 February 2009

Scar prevention by laser-assisted scar healing (LASH) using thermal post-conditioning

Alban Gossé, Gwen Iarmarcovai, Alexandre Capon, Alain Cornil, Serge Mordon

Proc. SPIE. 7175, Optical Interactions with Tissue and Cells XX

KEYWORDS: Proteins, Safety, Wound healing, Laser therapeutics, Tissues, Surgery, Skin, Abdomen, Temperature metrology, Clinical trials

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SPIE Journal Paper | 1 November 2007

Evaluation of BCECF fluorescence ratio imaging to properly measure gastric intramucosal pH variations in vivo

Philippe Rochon, Mercé Jourdain, Jacques Mangalaboyi, Francois Fourrier, Sylvie Soulie-Begu, Bruno Buys, Guy Dehlin, Jean Lesage, Marie Chambrin, Serge Mordon

JBO Vol. 12 Issue 06

KEYWORDS: Luminescence, In vivo imaging, Blood, Tissues, Video, Imaging systems, Calibration, Endoscopy, Hemodynamics, Control systems

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SPIE Journal Paper | 1 March 2006

Raman microspectrometry of laser-reshaped rabbit auricular cartilage: preliminary study on laser-induced cartilage mineralization

Michal Heger, Serge Mordon, Gérard Leroy, Laurence Fleurisse, Collette Creusy

JBO Vol. 11 Issue 02

KEYWORDS: Cartilage, Crystals, Laser crystals, Raman spectroscopy, Calcium, Laser irradiation, Apatite, Carbonates, Proteins, Crystallography

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SPIE Journal Paper | 1 March 2005

Fluorescence imaging method for in vivo pH monitoring during liposomes uptake in rat liver using a pH-sensitive fluorescent dye

Sylvie Begu, Serge Mordon, Thomas Desmettre, Jean-Marie Devoisselle

JBO Vol. 10 Issue 02

KEYWORDS: Luminescence, Liver, In vivo imaging, Blood, Skin, Tissues, In vitro testing, Spectroscopy, Veins, Imaging spectroscopy

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Proceedings Article | 14 October 2003

Development of a fluorescence endoscopic system for pH mapping of gastric tissue

Philippe Rochon, Serge Mordon, Bruno Buys, Guy Dhelin, Jean Lesage, Claude Chopin

Proc. SPIE. 5143, Novel Optical Instrumentation for Biomedical Applications

KEYWORDS: Endoscopy, Optical filters, Tissues, Imaging systems, Cameras, Calibration, Luminescence, Lamps, Hypoxia, In vivo imaging

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Proceedings Article | 15 October 2002

Nonablative remodeling: a 14-month clinical ultrasound-imaging profilometric evaluation of a 1540-nm Er:Glass laser

Nathalie Fournier, Serge Dahan, Gilbert Barneon, Celine Rouvrais, Stephane Diridollou, Jean-Michel Lagarde, Serge Mordon

Proc. SPIE. 4903, Laser Florence 2001: A Window on the Laser Medicine World

KEYWORDS: Cooling systems, Ultrasonography, Skin, Silicon, Collagen, Semiconductor lasers, Tissue optics, Pulsed laser operation, Absorption, Anisotropy

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SPIE Journal Paper | 1 October 2002

Noninvasive fluorescent study in situ and in real time of glucose effects on the pharmacokinetic of calcein

Sylvie Begu, Jean-Marie Devoisselle, Serge Mordon

JBO Vol. 7 Issue 04

KEYWORDS: Tissues, Luminescence, Tumors, Glucose, Blood, In vivo imaging, Fluorescence spectroscopy, Spectroscopy, Fluorescent markers, Charge-coupled devices

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Proceedings Article | 17 June 2002

Experimental evaluation of site-specific delivery of methylene blue to the hair follicles using fluorescence imaging

Serge Mordon, Jean-Marie Devoisselle, Valerie Mitchell

Proc. SPIE. 4609, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XII

KEYWORDS: Optical filters, Atrial fibrillation, Skin, Microscopy, Luminescence, Silicon, Diffusion, Bioalcohols, Biopsy, Image filtering

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Proceedings Article | 5 June 2002

Intravital fluorescence microscopic study of the behavior of long-circulating liposomes during microvascular thrombosis

Jean-Marie Dvoisselle, Sylvie Begu, Corine Tourne-Peteilh, Bruno Buys, Serge Mordon

Proc. SPIE. 4623, Functional Monitoring and Drug-Tissue Interaction

KEYWORDS: Tumors, Blood, Blood vessels, Skin, Microscopy, Luminescence, Inflammation, Blood circulation, In vivo imaging, In vitro testing

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Proceedings Article | 21 May 2001

1.9-um diode-laser-assisted anastomoses (LAMA) in reconstructive microsurgery: results of the preliminary clinical study

Serge Mordon, Michel Schoofs, Veronique Martinot, Alexandre Capon, Bruno Buys, Philippe Patenotre, P. Pellerin

Proc. SPIE. 4244, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XI

KEYWORDS: Veins, Doppler effect, Tissues, Surgery, Argon ion lasers, Laser welding, Arteries, Collagen, Semiconductor lasers, Microsurgery

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Proceedings Article | 21 May 2001

Granulation tissue exhibits differences in alpha-smooth muscle actin expression after laser-assisted skin closure (LASC)

Serge Mordon, Alexandre Capon, Laurence Fleurisse, Collette Creusy

Proc. SPIE. 4244, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XI

KEYWORDS: Wound healing, Tissues, Surgery, Skin, Molecules, Collagen, Laser irradiation, Inflammation, Adhesives, Laser tissue interaction

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Proceedings Article | 10 May 2001

Behavior of platelets stained by 5,6-CF-encapsulated PEGylated liposomes after laser irradiation of vessel wall: an in-vivo model for studying site-selective delivery of diagnostic or therapeutic a

Serge Mordon, Sylvie Begu, Bruno Buys, Corine Tourne-Peteilh, Jean-Marie Devoisselle

Proc. SPIE. 4260, Optical Diagnostics of Living Cells IV

KEYWORDS: Microscopes, Blood, Blood vessels, Skin, Microscopy, Luminescence, Laser irradiation, Inflammation, Digital video recorders, In vivo imaging

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Vascular endothelium serves as an extensive interface between circulating blood and various tissues and organs of the body. As such, it offers an accessible target for blood-borne pharmacological and genetic manipulations that can mediate both local and systemic effects. Thus, targeting of liposomes to activated vascular endothelial cells may provide a strategy for site-selective delivery in the vascular system with broad therapeutic applicability. This study aimed to evaluate an intravital fluorescence imaging technique to visualize in-situ and in real-time the activation of platelets after staining by 5,6-CF- encapsulated PEGylated liposomes injected intravenously. The study was performed on skin by using a dorsal skin-fold chamber implanted in golden hamsters using intravital microscopy. The skin micro circulation was observed with an intravital microscope (using x25 and x40 magnification) fitted with a Xenon light source and an epi-fluorescence assembly. An ultra-high sensitivity video-camera mounted on the microscope projected the image onto a monitor, and the images were recorded for play-back analysis with a digital video cassette recorder. An inflammatory response was induced by an Argon laser emitting at 514.5nm. The 80micrometers laser beam was focused on a vessel and its position was controlled with the microscope imaging system, it was possible to see individual platelets flowing in blood vessels. As liposomes were labeled with a fluorescent probe which was hydrophilic (located in the aqueous phase), the fluorescence of platelets was due only to the uptake of liposomes. After laser irradiation, platelets activation at sites of vascular injury was obtained. Tethering, translocation of some platelets inside the irradiated zone were clearly seen. At last, detachment and extravasation of platelets were observed. A perivascular fluorescence confirmed that platelets migrated across the basal lamina into the dermal connective tissue. In conclusion, staining of platelets using 5,6-CF-encapsulated PEGylated liposomes injected intravenously presents the following advantages: i) in-situ labeling, ii) use of hydrophilic marker located in an aqueous compartment within the platelet, iii) as the release of the fluorescence marker is slow due to the formulation of liposomes, labeling of platelets could be observed during the whole experiment. Laser irradiation of blood vessels in vivo can induce the different phases of platelet activation: i) recruitment, ii) adhesion, iii) detachment, iv) transmigration. The combination of these techniques (platelet staining with PEGylated liposomes, intravital fluorescence microscopy, laser irradiation) provides a powerful tool to study local inflammation, platelet activation and behavior of liposomes in situ and in real time at an inflammation site. These observations could be considered as a preliminary approach to study the targeting of drugs to an endothelium under inflammation environment.

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Proceedings Article | 17 May 2000

In-vivo experimental evaluation of nonablative skin remodeling using a 1.54-um laser with surface cooling

Serge Mordon, Alexandre Capon, Collette Creusy, Laurence Fleurisse, Bruno Buys, Marc Faucheux, Pascal Servell

Proc. SPIE. 3907, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems X

KEYWORDS: Cooling systems, Injuries, Skin, Ions, Nd:YAG lasers, Collagen, Semiconductor lasers, In vivo imaging, Pulsed laser operation, Absorption

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Proceedings Article | 27 April 2000

Direct observation of liposome uptake by leukocytes in vivo in skin blood vessels using intravital fluorescence microscopy

Jean-Marie Devoisselle, Serge Mordon, Sylvie Begu, Thomas Desmettre

Proc. SPIE. 3921, Optical Diagnostics of Living Cells III

KEYWORDS: Microscopes, Tissues, Blood, Blood vessels, Skin, Microscopy, Luminescence, Inflammation, Digital video recorders, In vivo imaging

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Proceedings Article | 12 February 1999

Fluorescence endoscopic imaging for evaluation of gastric mucosal blood flow: a preliminary study

Nicolas Bocquillon, Serge Mordon, D. Mathieu, Vincent Maunoury, Xavier-Marie Marechal, Remi Neviere, Francis Wattel, Claude Chopin

Proc. SPIE. 3567, Optical and Imaging Techniques for Biomonitoring IV

KEYWORDS: Endoscopy, Optical filters, Tissues, Blood, Video, Luminescence, Blood circulation, Angiography, Digital video recorders, Sodium

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Proceedings Article | 12 February 1999

Endoscopic fluorescence imaging for early assessment of anastomotic recurrence of Crohn's disease

Serge Mordon, Vincent Maunoury, K. Geboes, Olivier Klein, P. Desreumaux, A. Debaert, Jean-Frederic Colombel

Proc. SPIE. 3567, Optical and Imaging Techniques for Biomonitoring IV

KEYWORDS: Endoscopy, Light sources, Surgery, Luminescence, Interference filters, Biopsy, Inflammation, Angiography, Colon, Lymphatic system

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Proceedings Article | 12 February 1999

Fluorescence imaging microscopy of leukocytes-endothelium interaction in rat mesenteric microcirculation after endotoxin injection: role of inhaled nitric oxide

Serge Mordon, Remi Neviere, Xavier-Marie Marechal, Bruno Buys, Guy Dhelin, Jean Lesage, D. Mathieu, Benoit Guery, Claude Chopin

Proc. SPIE. 3567, Optical and Imaging Techniques for Biomonitoring IV

KEYWORDS: Injuries, Tissues, Blood, Microscopy, Luminescence, Molecules, Lung, NOx, In vivo imaging, Adhesives

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Proceedings Article | 12 February 1999

Intestine pH measurements using fluorescence imaging: an in-vivo preliminary study

Xavier-Marie Marechal, Serge Mordon, Jean-Marie Devoisselle, Sylvie Begu, D. Mathieu, Bruno Buys, Guy Dhelin, Jean Lesage, Remi Neviere, Claude Chopin

Proc. SPIE. 3567, Optical and Imaging Techniques for Biomonitoring IV

KEYWORDS: Tissues, Cameras, Calibration, Blood, Luminescence, Hemodynamics, Intestine, In vivo imaging, Tissue optics, Absorption

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Proceedings Article | 4 February 1999

Laser skin resurfacing using a frequency-doubled Nd:YAG laser after topical application of an exogenous chromophore

Chryslain Sumian, Franck Pitre, Beatrice Gauthier, Martine Bouclier, Serge Mordon

Proc. SPIE. 3564, Medical Applications of Lasers in Dermatology, Cardiology, Ophthalmology, and Dentistry II

KEYWORDS: Carbon, Wound healing, Skin, Particles, Nd:YAG lasers, Chromophores, Laser ablation, YAG lasers, Er:YAG lasers, Neodymium

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Proceedings Article | 4 February 1999

Laser skin resurfacing using a frequency-doubled Nd:YAG laser after application of a chromofilm

Chryslain Sumian, Franck Pitre, Beatrice Gauthier, Jean Levy, Martine Bouclier, Serge Mordon

Proc. SPIE. 3564, Medical Applications of Lasers in Dermatology, Cardiology, Ophthalmology, and Dentistry II

KEYWORDS: Carbon, Injuries, Tissues, Skin, Carbon dioxide lasers, Collagen, Chromophores, Laser irradiation, YAG lasers, Neodymium

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Proceedings Article | 4 February 1999

Interest of ICG blood clearance monitoring for reproducible 810-nm diode laser coagulation of blood vessels

Thomas Desmettre, Sylvie Soulie-Begu, Jean-Marie Devoisselle, Serge Mordon

Proc. SPIE. 3564, Medical Applications of Lasers in Dermatology, Cardiology, Ophthalmology, and Dentistry II

KEYWORDS: Laser coagulation, Data modeling, Blood, Blood vessels, Dermatology, Skin, Indocyanine green, Semiconductor lasers, Chromophores, Laser tissue interaction

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Proceedings Article | 4 January 1999

Laser-assisted skin closure (LASC) using a 815-nm diode laser system: determination of an optimal dose to accelerate wound healing

Alexandre Capon, Valerie Mitchell, Chryslain Sumian, Beatrice Gauthier, Serge Mordon

Proc. SPIE. 3565, Thermal Therapy, Laser Welding, and Tissue Interaction

KEYWORDS: Wound healing, Tissues, Surgery, Skin, Photography, Laser applications, Nd:YAG lasers, Laser welding, Semiconductor lasers, Laser systems engineering

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Proceedings Article | 14 January 1998

1.9-um diode-laser-assisted anastomoses in reconstructive microsurgery: preliminary results in 12 patients

Serge Mordon, Michel Schoffs, Veronique Martinot, Bruno Buys, Philippe Patenotre, Jean Lesage, Guy Dhelin

Proc. SPIE. 3195, Laser-Tissue Interaction, Tissue Optics, and Laser Welding III

KEYWORDS: Veins, Tissues, Surgery, Argon ion lasers, Laser welding, Arteries, Collagen, Semiconductor lasers, Chromophores, Microsurgery

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Proceedings Article | 14 January 1998

805-nm diode-laser-induced release of liposome-encapsulated dye for quantification of chorioretinal thermal damage: in-vivo study on a rabbit eye model

Serge Mordon, Thomas Desmettre, Jean-Marie Devoisselle, Sylvie Begu, Valerie Mitchell

Proc. SPIE. 3195, Laser-Tissue Interaction, Tissue Optics, and Laser Welding III

KEYWORDS: Ophthalmology, Laser coagulation, Tissues, Retina, Luminescence, Semiconductor lasers, In vivo imaging, Eye models, Laser tissue interaction, Temperature metrology

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Proceedings Article | 16 June 1997

Thermal damage assessment of blood vessels in a hamster skin flap model by fluorescence measurement of a liposome-dye system

Serge Mordon, Thomas Desmettre, Jean-Marie Devoisselle, Sylvie Soulie-Begu

Proc. SPIE. 2975, Laser-Tissue Interaction VIII

KEYWORDS: Laser coagulation, Tissues, Blood vessels, Skin, Luminescence, Photography, Semiconductor lasers, Laser irradiation, Temperature metrology, Absorption

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The present study was undertaken to evaluate the feasibility of thermal damage assessment of blood vessels by using laser-induced release of liposome-encapsulated dye. Experiments were performed in a hamster skin flap model. Laser irradiation was achieved with a 300micrometers fiber connected to a 805nm diode laser after potentiation using a specific indocyanine green (ICG) formulation. Liposomes- encapsulated carboxyfluorescein were prepared by the sonication procedure. Carboxyfluorescein was loaded at high concentration in order to quench its fluorescence. The measurements were performed after i.v. injection of DSPC liposomes and lasted 40 minutes. Fluorescence emission was measured with an ultra high sensitivity intensified camera. Three different shapes of fluorescent spots were identified depending on target and energy deposition in tissue: (i) intravascular fluorescence, (ii) transient low fluorescence circular spot and (iii) persistent high intense fluorescence spot. These images are correlated with histological data. The advantages of this liposome-dye system are (1) direct measurements can be obtained, (2) several repeated readings can be made from one injection, (3) continuous monitoring of the fluorescence can be made, (4) temperature-sensitive range can be adapted using different liposomes compositions, (5) circulation times of several hours can be achieved using DSPC liposomes (6) the tissue microcirculation and the vessel macrocirculation can be investigated simultaneously, therefore changes in response to a treatment regimen and/or ICG formulations can be detected. One main constraint exists: the fluorescent dye encapsulated into the liposomes has to be carefully chosen in order to avoid any direct absorption by the dye itself. In conclusion, one of the most significant applications of this experimental technique is the evaluation of various degrees of tissue thermal damage. It could be possible to consider the application of this technique in ophthalmology and dermatology and possibly for the evaluation of burn injury.

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Proceedings Article | 7 May 1997

Fluorescent characteristics and pharmacokinetic profiles of the fluorescent probe BCECF in various tissues: the role of blood content

Jean-Marie Devoisselle, Sylvie Soulie-Begu, Serge Mordon, H. Maillols

Proc. SPIE. 2980, Advances in Fluorescence Sensing Technology III

KEYWORDS: Optical fibers, Liver, Tissues, Blood, Blood vessels, Skin, Luminescence, In vivo imaging, In vitro testing, Absorption

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Proceedings Article | 7 May 1997

Fluorescence properties of indocyanin green: II. In-vitro study related to in-vivo behavior

Jean-Marie Devoisselle, Sylvie Soulie-Begu, H. Maillols, Thomas Desmettre, Serge Mordon

Proc. SPIE. 2980, Advances in Fluorescence Sensing Technology III

KEYWORDS: Endoscopy, Proteins, Blood, Luminescence, Molecules, Angiography, In vivo imaging, In vitro testing, Plasma, Absorption

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Proceedings Article | 7 May 1997

Fluorescence properties of indocyanin green: I. In-vitro study with micelles and liposomes

Jean-Marie Devoisselle, Sylvie Soulie-Begu, Serge Mordon, Thomas Desmettre, H. Maillols

Proc. SPIE. 2980, Advances in Fluorescence Sensing Technology III

KEYWORDS: Proteins, Tissues, Luminescence, Molecules, Interfaces, Angiography, In vivo imaging, Molecular interactions, In vitro testing, Absorption

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Proceedings Article | 19 January 1996

End-to-end microvascular anastomoses with a 1.9-un diode laser

Serge Mordon, Veronique Martinot, Valerie Mitchell

Proc. SPIE. 2623, Medical Applications of Lasers III

KEYWORDS: Carbon dioxide, Veins, Argon ion lasers, Nd:YAG lasers, Laser welding, Carbon dioxide lasers, Arteries, Semiconductor lasers, Laser tissue interaction, Absorption

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Proceedings Article | 19 January 1996

Tissue welding for corneal wound suture with a CW 1.9-um diode laser: an in-vivo preliminary study

Thomas Desmettre, Serge Mordon, Valerie Mitchell

Proc. SPIE. 2623, Medical Applications of Lasers III

KEYWORDS: Monochromatic aberrations, Eye, Continuous wave operation, Cornea, Tissues, Laser welding, Collagen, Semiconductor lasers, In vivo imaging, Laser tissue interaction

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Proceedings Article | 27 December 1995

Fluorescence endoscopic imaging study of anastomotic recurrence of Crohn's disease after right ileocolonic resection

Serge Mordon, Vincent Maunoury, Olivier Klein, Jean-Frederic Colombel

Proc. SPIE. 2627, Optical Biopsies

KEYWORDS: Endoscopy, Ischemia, Cameras, Luminescence, Diffusion, Interference filters, Endoscopes, Blood circulation, In vivo imaging, Sodium

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Proceedings Article | 27 December 1995

In vivo pharmacokinetic study of two fluorescein derivatives by fluorescence spectroscopy

Sylvie Soulie-Begu, Jean-Marie Devoisselle, Serge Mordon

Proc. SPIE. 2627, Optical Biopsies

KEYWORDS: Veins, Liver, Tissues, Blood, Skin, Luminescence, Fluorescence spectroscopy, Imaging spectroscopy, In vivo imaging, Tissue optics

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SPIE Conference Volume | 27 December 1995

Optical Biopsies

Proceedings Article | 27 December 1995

Effect of indocyanin green formulation on blood clearance and in vivo fluorescence kinetic profile of skin

Jean-Marie Devoisselle, Sylvie Soulie-Begu, Serge Mordon, G. Mestres, Thomas Desmettre, H. Maillols

Proc. SPIE. 2627, Optical Biopsies

KEYWORDS: Liver, Tissues, Blood, Blood vessels, Skin, Particles, Luminescence, In vivo imaging, Tissue optics, Absorption

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Proceedings Article | 22 May 1995

Fluorescence measurement of diode (805 nm) laser-induced release of 5,6-CF from DSPC liposomes for monitoring of temperature: an in vivo study in rat liver using indocyanine green potentiation

Serge Mordon, Thomas Desmettre, Jean-Marie Devoisselle, Sylvie Soulie-Begu

Proc. SPIE. 2391, Laser-Tissue Interaction VI

KEYWORDS: Liver, Tissues, Luminescence, Indocyanine green, Semiconductor lasers, Laser irradiation, Diodes, In vivo imaging, Laser tissue interaction, Temperature metrology

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Proceedings Article | 12 April 1995

In-vivo and ex-vivo spectrofluorometric and imaging study of liposome uptake by the liver using a pH-sensitive probe

Sylvie Soulie-Begu, Jean-Marie Devoisselle, Serge Mordon

Proc. SPIE. 2387, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II

KEYWORDS: Veins, Liver, Tissues, Imaging systems, Blood, Luminescence, Fluorescence spectroscopy, Imaging spectroscopy, In vivo imaging, In vitro testing

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Proceedings Article | 1 March 1995

In vivo fluorescence imaging of lysosomes: a potential technique to follow dye accumulation in the context of PDT?

Jean-Marie Devoisselle, Serge Mordon, Sylvie Soulie-Begu

Proc. SPIE. 2371, 5th International Photodynamic Association Biennial Meeting

KEYWORDS: Veins, Photodynamic therapy, Liver, Tumors, Tissues, Microscopy, Luminescence, Fluorescence spectroscopy, Imaging spectroscopy, In vivo imaging

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Proceedings Article | 10 February 1995

Zirconium fluoride glass fiber radiometer for low-temperature measurement

A. El Khoniss, Serge Mordon, Guy Dhelin, Bruno Buys, Jean Lesage

Proc. SPIE. 2331, Medical Sensors II and Fiber Optic Sensors

KEYWORDS: Sensors, Glasses, Fiber optics sensors, Signal processing, Black bodies, Infrared radiation, Radiometry, Zirconium, Signal detection, Temperature metrology

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Proceedings Article | 18 January 1995

Laser-induced release of liposome-encapsulated dye to monitor tissue temperature: study of different liposome compositions

Thomas Desmettre, Serge Mordon, Jean-Marie Devoisselle, Sylvie Soulie-Begu

Proc. SPIE. 2323, Laser Interaction with Hard and Soft Tissue II

KEYWORDS: Veins, Liver, Tissues, Imaging systems, Cameras, Luminescence, Laser irradiation, Laser tissue interaction, Temperature metrology, Absorption

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Proceedings Article | 18 January 1995

In vivo cw Nd:YAG volatilization: quantification using surface temperature measurements and histology

Claire Beacco, Serge Mordon, Valerie Mitchell, Jean Marc Brunetaud

Proc. SPIE. 2323, Laser Interaction with Hard and Soft Tissue II

KEYWORDS: Continuous wave operation, Liver, Tissues, Nd:YAG lasers, In vivo imaging, Natural surfaces, Laser tissue interaction, In vitro testing, Temperature metrology

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Proceedings Article | 12 January 1995

Laser photocoagulation around extra foveolar foci of toxoplasma retinochoroiditis: a way to decrease frequency of recurrence

P. Labalette, Thomas Desmettre, Serge Mordon, G. Constantinides

Proc. SPIE. 2330, Lasers in Ophthalmology II

KEYWORDS: Surface plasmons, Ophthalmology, Medical laser equipment, Laser coagulation, Visualization, Satellites, Argon ion lasers, Inflammation, Therapeutics, Francium

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Proceedings Article | 4 January 1995

Fluorescence spectroscopy and imaging of pH in vivo using a dual emission fluorophore (C-SNAFL-1)

Serge Mordon, Jean-Marie Devoisselle, Sylvie Soulie-Begu

Proc. SPIE. 2324, Optical Biopsy and Fluorescence Spectroscopy and Imaging

KEYWORDS: Glucose, Tumors, Tissues, Imaging systems, Cameras, Spectroscopy, Luminescence, Fluorescence spectroscopy, Imaging spectroscopy, In vivo imaging

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Proceedings Article | 4 January 1995

Changes in muscle tissue oxygenation assessed by near-infrared spectroscopy (NIRS)

Benoit Vallet, Jacques Mangalaboyi, Patrick Menager, Scott Curtis, Claude Chopin, Serge Mordon

Proc. SPIE. 2324, Optical Biopsy and Fluorescence Spectroscopy and Imaging

KEYWORDS: Ischemia, Tissues, Arteries, Oxygen, Hypoxia, Blood circulation, Near infrared spectroscopy, Tissue optics, Absorption, Oxidation

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SPIE Conference Volume | 4 January 1995

Optical Biopsy and Fluorescence Spectroscopy and Imaging

Proceedings Article | 4 January 1995

Noninvasive tissue fluorescence study of a fluorescent dye (calcein) on intraperitoneal glucose administration

Jean-Marie Devoisselle, Serge Mordon, Sylvie Soulie-Begu

Proc. SPIE. 2324, Optical Biopsy and Fluorescence Spectroscopy and Imaging

KEYWORDS: Glucose, Tumors, Tissues, Blood, Luminescence, Fluorescence spectroscopy, Imaging spectroscopy, Blood circulation, In vivo imaging, Tissue optics

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Proceedings Article | 23 December 1994

Skin surface microscopy of port wine stains: preliminary data on classification and assessment of laser therapy results

Guy Rotteleur, P. Huan, Serge Mordon, Claire Beacco, Jean Marc Brunetaud

Proc. SPIE. 2327, Medical Applications of Lasers II

KEYWORDS: Minerals, Laser therapeutics, Medical laser equipment, Capillaries, Skin, Microscopy, Laser applications, Inspection, Biopsy, Tissue optics

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Proceedings Article | 23 December 1994

Study of venous and carotid anastomoses in rats using an argon laser

Veronique Martinot, Valerie Mitchell, Serge Mordon, P. Pellerin, Jean Marc Brunetaud

Proc. SPIE. 2327, Medical Applications of Lasers II

KEYWORDS: Microscopes, Veins, Medical laser equipment, Patents, Blood, Argon ion lasers, Laser applications, Laser welding, Arteries, In vivo imaging

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Proceedings Article | 23 December 1994

Software for port wine stains laser treatment assessment

Claire Beacco, Guy Rotteleur, J. Beani, Frederic Laffitte, Dominique Teillac-Hamel, Serge Mordon, Dominique Cochelard, Jean Marc Brunetaud

Proc. SPIE. 2327, Medical Applications of Lasers II

KEYWORDS: Neck, Continuous wave operation, Laser therapeutics, Medical laser equipment, Skin, Dye lasers, Argon ion lasers, Laser applications, Electroluminescence, Software development

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Proceedings Article | 17 August 1994

Laser-triggered releasing of fluorescein from thermosensible liposomes: a new method for quantification of laser-induced photocoagulation

Serge Mordon, Thomas Desmettre, Jean-Marie Devoisselle, G. Constantinides, Jean Marc Brunetaud

Proc. SPIE. 2134, Laser-Tissue Interaction V; and Ultraviolet Radiation Hazards

KEYWORDS: Liver, Laser coagulation, Imaging systems, Cameras, Luminescence, Nd:YAG lasers, In vivo imaging, Thermal imaging cameras, Thermal modeling, Temperature metrology

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Proceedings Article | 19 May 1994

In-vivo fluorescence imaging of normal and tumorous tissue using a pH-sensitive probe

Serge Mordon, Jean-Marie Devoisselle, Vincent Maunoury

Proc. SPIE. 2135, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases

KEYWORDS: Glucose, Tumors, Tissues, Calibration, Spectroscopy, Luminescence, Fluorescence spectroscopy, In vivo imaging, Tissue optics, In vitro testing

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Proceedings Article | 27 August 1993

Study of experimental endometriosis using fluorescence of eosin-tamoxifen association

A. Brogniez, Serge Mordon, Jean-Marie Devoisselle, Denis Querleu, Jean Marc Brunetaud

Proc. SPIE. 1887, Physiological Imaging, Spectroscopy, and Early-Detection Diagnostic Methods

KEYWORDS: Breast, Magnesium, Statistical analysis, Tumors, Tissues, Luminescence, Receptors, Tissue optics, In vitro testing, Laparoscopy

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Proceedings Article | 7 July 1993

Experimental Study of Nd:YAG laser volatilization

Claire Beacco, Serge Mordon, Jean Marc Brunetaud

Proc. SPIE. 1882, Laser-Tissue Interaction IV

KEYWORDS: Liver, Tissues, Nd:YAG lasers, Carbon dioxide lasers, Combustion, Laser ablation, Thermal effects, Natural surfaces, Laser tissue interaction, Temperature metrology

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Proceedings Article | 28 May 1993

Determination of optimal parameters for argon-laser-assisted carotid anastomoses in rats: macroscopic, thermal, and histological evaluation

Veronique Martinot, Serge Mordon, Valerie Mitchell, P. Pellerin, Jean Marc Brunetaud

Proc. SPIE. 1879, Lasers in Urology, Gynecology, and General Surgery

KEYWORDS: Laser therapeutics, Laser vision correction, Tissues, Surgery, Blood, Argon ion lasers, Laser welding, Carbon dioxide lasers, Semiconductor lasers, Temperature metrology

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SPIE Journal Paper | 1 February 1993

Measurement of in vivo tumorous/normal tissue pH by localized spectroscopy using a fluorescent marker

Jean-Marie Devoisselle, Vincent Maunoury, Serge Mordon, Denise Coustaut

OE Vol. 32 Issue 02

KEYWORDS: Tumors, Tissues, Luminescence, In vivo imaging, In vitro testing, Tissue optics, Fluorescent markers, Glucose, Spectroscopy, Optical fibers

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Proceedings Article | 7 August 1992

Self-tuning control of Nd:YAG laser coagulation: principle

Radouan Faiz, Serge Mordon, Marcel Staroswiecki, Jean Marc Brunetaud

Proc. SPIE. 1646, Laser-Tissue Interaction III

KEYWORDS: Tissues, Nd:YAG lasers, Control systems, Computer programming, Computer simulations, Optimization (mathematics), Natural surfaces, Laser tissue interaction, Beam controllers, Temperature metrology

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Proceedings Article | 7 August 1992

Development and experimental in-vivo evaluation of mathematical modeling of coagulation by laser

Claire Beacco, Serge Mordon, Jean Marc Brunetaud

Proc. SPIE. 1646, Laser-Tissue Interaction III

KEYWORDS: Mathematical modeling, Tissues, Scattering, Light scattering, Argon ion lasers, Nd:YAG lasers, In vivo imaging, Tissue optics, Laser tissue interaction, Absorption

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Proceedings Article | 1 June 1992

Experience in the 532-nm green laser treatment of cutaneous angiodysplasias using an automatic delivery system

Serge Mordon, Marie Suchet-Lopez, Guy Rotteleur, Jean Marc Brunetaud

Proc. SPIE. 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III

KEYWORDS: Laser therapeutics, Blood, Argon, Dye lasers, Argon ion lasers, Nd:YAG lasers, Fourier transforms, Tissue optics, Pulsed laser operation, Absorption

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Proceedings Article | 16 April 1992

Study of normal/tumorous tissue fluorescence using a pH-dependent fluorescent probe in vivo

Serge Mordon, Vincent Maunoury, Jean-Marie Devoisselle, Y. Abbas, Denise Coustaut

Proc. SPIE. 1648, Fiber Optic Medical and Fluorescent Sensors and Applications

KEYWORDS: Glucose, Tumors, Fiber optics, Tissues, Sensors, Calibration, Luminescence, Fiber optics sensors, In vivo imaging, Tissue optics

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Proceedings Article | 1 June 1990

On-off time control of laser pulses for pseudo-constant temperature coagulation in tissue

Gilwon Yoon, Serge Mordon, Jean Marc Brunetaud, Radouan Faiz, Richard Straight, Pierre Bugnon, Marcel Staroswiecki, J. Leroux

Proc. SPIE. 1202, Laser-Tissue Interaction

KEYWORDS: Tissues, Cameras, Thulium, Tissue optics, Pulsed laser operation, Natural surfaces, Thermal modeling, Laser tissue interaction, Beam controllers, Temperature metrology

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Showing 5 of 67 publications

Conference Committee Involvement (9)

17th International Photodynamic Association World Congress

28 June 2019 | Cambridge, Massachusetts, United States

Translation of Lasers and Biophotonics Technologies and Procedures: Toward the Clinic

23 June 2019 | Munich, Germany

Medical Laser Applications and Laser-Tissue Interactions VIII

25 June 2017 | Munich, Germany

Medical Laser Applications and Laser-Tissue Interactions VII

21 June 2015 | Munich, Germany

Medical Laser Applications and Laser-Tissue Interactions VI

12 May 2013 | Munich, Germany

Showing 5 of 9 published special sections

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