Based on the Temperature Independent Spectral Index (TISI) method, the inversion of land surface emissivity was performed with MODIS infrared data over the Taklimakan Desert. In the process of land surface emissivity retrieval, the RossThick-LiSparseR BRDF model and the modified Minneart’s BRDF model were used to calculate the surface albedo. The retrieved emissivities were compared with MODIS emissivity products. The results show that the inversion error is small when the RossThick-LiSparseR model is been used, the average errors of the channels 31 and 32 are 0.0084 and 0.0023, respectively, and the emissivity decreases with the increase of the observation angle. By using the modified Minneart’s BRDF model, the average error of channels 31、32 are 0.0364,0.0259 respectively.