Arrays of hierarchical microstructures are considered nowadays as an effective method to create hydrophobic surfaces. Herein, we use femtosecond 3D printing to manufacture microstructures in different geometric patterns. Direct laser writing and, in particular, multiphoton polymerization lithography (MPL) with ultrafast laser pulses has taken additive manufacturing all the way down to the sub-micrometer scale. MPL is a 3D nanoscale manufacturing tool offering great potential for rapid prototyping and the manufacture of photonic devices, tissue scaffolds and biomechanical parts. In this study, we demonstrate the tuning of the wetting performance of surfaces via trichomes designs of 3D microstructures.