Dr. Stavros G. Demos Profile

Dr. Stavros G. Demos

Senior Scientist at Univ of Rochester

SPIE Involvement:

Conference Chair | Conference Program Committee | Conference Co-Chair | Author | Editor

Publications (99)

PROCEEDINGS ARTICLE | February 19, 2018

Multi-color autofluorescence and scattering spectroscopy provides rapid assessment of kidney function following ischemic injury

Proc. SPIE. 10489, Optical Biopsy XVI: Toward Real-Time Spectroscopic Imaging and Diagnosis

KEYWORDS: Injuries, Ischemia, Tissues, Scattering, Blood, Spectroscopy, Ultraviolet radiation, Signal processing, Kidney, Absorption

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PROCEEDINGS ARTICLE | December 20, 2017

Damage testing of nematic liquid crystalline materials for femtosecond to nanosecond pulse lengths at 1053 nm

Proc. SPIE. 10447, Laser-Induced Damage in Optical Materials 2017

KEYWORDS: Femtosecond phenomena, Laser induced damage, Liquid crystals, Laser damage threshold, Liquids

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PROCEEDINGS ARTICLE | December 11, 2017

Methods for improving the damage performance of fused silica polished by magnetorheological finishing

Proc. SPIE. 10447, Laser-Induced Damage in Optical Materials 2017

KEYWORDS: Polishing, Silica, Etching, Laser induced damage, Particles, Surface roughness, Wet etching, Laser damage threshold, Abrasives, Magnetorheological finishing, Surface finishing

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SPIE Journal Paper | May 3, 2017

Predictive assessment of kidney functional recovery following ischemic injury using optical spectroscopy

Raman, Rajesh , Pivetti, Christopher , Ramsamooj, Rajendra , Troppmann, Christoph , Demos, Stavros

JBO Vol. 22 Issue 05

KEYWORDS: Kidney, Injuries, Blood, Atrial fibrillation, Tissues, Tissue optics, Ischemia, Absorption, Scattering, Light scattering

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SPIE Conference Volume | April 4, 2017

Optical Biopsy XV: Toward Real-Time Spectroscopic Imaging and Diagnosis

PROCEEDINGS ARTICLE | December 6, 2016

Laser-matter coupling mechanisms governing particulate-induced damage on optical surfaces

Proc. SPIE. 10014, Laser-Induced Damage in Optical Materials 2016

KEYWORDS: Silica, Scattering, Metals, Particles, Light scattering, Laser scattering, Aluminum, Pulsed laser operation, Plasma, Near field optics

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SPIE Journal Paper | September 8, 2016

Morphology of ejected particles and impact sites on intercepting substrates following exit-surface laser damage with nanosecond pulses in silica

Demos, Stavros G. , Negres, Raluca

OE Vol. 56 Issue 01

KEYWORDS: Particles, Silica, Laser induced damage, Scanning electron microscopy, Fusion energy, Liquids, Optical engineering, Laser energy, Explosives, Laser systems engineering

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SPIE Conference Volume | June 6, 2016

Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis

PROCEEDINGS ARTICLE | April 26, 2016

Slide-free histology via MUSE: UV surface excitation microscopy for imaging unsectioned tissue (Conference Presentation)

Proc. SPIE. 9703, Optical Biopsy XIV: Toward Real-Time Spectroscopic Imaging and Diagnosis

KEYWORDS: Confocal microscopy, Multiphoton microscopy, Tissues, Optical coherence tomography, Ultraviolet radiation, Microscopy, Image resolution, Nondestructive evaluation, Tissue optics, Natural surfaces

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PROCEEDINGS ARTICLE | November 23, 2015

Morphology of ejected debris from laser super-heated fused silica following exit surface laser-induced damage

Proc. SPIE. 9632, Laser-Induced Damage in Optical Materials: 2015

KEYWORDS: Optical fibers, Foam, Silica, Laser induced damage, Particles, Dielectrics, Materials processing, Scanning electron microscopy, Explosives, Pulsed laser operation, Temperature metrology, Laser systems engineering, Liquids

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PROCEEDINGS ARTICLE | November 23, 2015

Energetic laser cleaning of metallic particles and surface damage on silica optics: investigation of the underlying mechanisms

Proc. SPIE. 9632, Laser-Induced Damage in Optical Materials: 2015

KEYWORDS: Iron, Silica, Metals, Laser energy, Particles, Silicon, Laser ablation, Pulsed laser operation, Atmospheric particles, Plasma

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SPIE Conference Volume | April 10, 2015

Optical Biopsy XIII: Toward Real-Time Spectroscopic Imaging and Diagnosis

PROCEEDINGS ARTICLE | March 11, 2015

Microscopy with UV Surface Excitation (MUSE) for slide-free histology and pathology imaging

Proc. SPIE. 9318, Optical Biopsy XIII: Toward Real-Time Spectroscopic Imaging and Diagnosis

KEYWORDS: Tunable lasers, Light emitting diodes, Tissues, Pathology, Ultraviolet radiation, Microscopy, Luminescence, Kidney, Tissue optics, Natural surfaces

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PROCEEDINGS ARTICLE | October 31, 2014

Modeling the material properties at the onset of damage initiation in bulk potassium dihydrogen phosphate crystals

Proc. SPIE. 9237, Laser-Induced Damage in Optical Materials: 2014

KEYWORDS: Potassium, Optical properties, Laser induced damage, Crystals, Laser damage threshold, Picosecond phenomena, Laser crystals, Performance modeling, Thermal modeling, Absorption

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SPIE Conference Volume | April 1, 2014

Optical Biopsy XII

PROCEEDINGS ARTICLE | March 17, 2014

Enhanced visualization of the bile duct via parallel white light and indocyanine green fluorescence laparoscopic imaging

Proc. SPIE. 8940, Optical Biopsy XII

KEYWORDS: Tissues, Surgery, Imaging systems, Cameras, Luminescence, Image acquisition, Endoscopes, Image enhancement, Laparoscopy, RGB color model

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PROCEEDINGS ARTICLE | December 2, 2013

Interaction of laser pulse with confined plasma during exit surface nanosecond laser damage

Proc. SPIE. 8885, Laser-Induced Damage in Optical Materials: 2013

KEYWORDS: Silica, Visualization, Laser induced damage, Laser energy, Particles, Dielectrics, Laser development, Pulsed laser operation, Plasma, Absorption

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PROCEEDINGS ARTICLE | November 14, 2013

Comparison of material response in fused silica and KDP following exit surface laser- induced breakdown

Proc. SPIE. 8885, Laser-Induced Damage in Optical Materials: 2013

KEYWORDS: Silica, Laser induced damage, Laser energy, Particles, Crystals, Materials processing, Pulsed laser deposition, Laser beam diagnostics, Plasma, Laser systems engineering

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SPIE Conference Volume | March 26, 2013

Optical Biopsy XI

SPIE Journal Paper | April 3, 2012

In vivo testing of a prototype system providing simultaneous white light and near infrared autofluorescence image acquisition for detection of bladder cancer

Jacobson, Michael , deVere White, Ralph , Demos, Stavros

JBO Vol. 17 Issue 03

KEYWORDS: Near infrared, Tumors, Tissues, Bladder, RGB color model, In vivo imaging, Luminescence, Atrial fibrillation, Visible radiation, Prototyping

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SPIE Conference Volume | March 1, 2012

Optical Biopsy X

PROCEEDINGS ARTICLE | February 17, 2012

In vivo imaging of bladder cancer using prototype endoscope-adaptable system providing parallel RGB and NIR autofluorescence image acquisition

Proc. SPIE. 8220, Optical Biopsy X

KEYWORDS: Near infrared, Visible radiation, Atrial fibrillation, Tumors, Tissues, Imaging systems, Bladder, In vivo imaging, Prototyping, RGB color model

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SPIE Journal Paper | February 13, 2012

Establishment of rules for interpreting ultraviolet autofluorescence microscopy images for noninvasive detection of Barrett's esophagus and dysplasia

Lin, Bevin , Matthews, Dennis , Demos, Stavros , Urayama, Shiro , Saroufeem, Ramez

JBO Vol. 17 Issue 1

KEYWORDS: Atrial fibrillation, Tissues, Biopsy, Esophagus, Ultraviolet radiation, Natural surfaces, Microscopy, Tissue optics, Endoscopy, Visualization

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PROCEEDINGS ARTICLE | November 23, 2011

Estimation of the transverse stimulated Raman scattering gain coefficient in KDP and DKDP at 2-omega, 3-omega, and 4-omega

Proc. SPIE. 8190, Laser-Induced Damage in Optical Materials: 2011

KEYWORDS: Polarization, Scattering, Laser induced damage, Crystals, Laser scattering, Raman spectroscopy, Raman scattering, Laser crystals, Harmonic generation, Laser systems engineering

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SPIE Journal Paper | April 1, 2011

Endomicroscopy imaging of epithelial structures using tissue autofluorescence

Lin, Bevin , Matthews, Dennis , Demos, Stavros , Urayama, Shiro , Saroufeem, Ramez

JBO Vol. 16 Issue 04

KEYWORDS: Tissues, Atrial fibrillation, Imaging systems, Tissue optics, Endomicroscopy, Biopsy, Ultraviolet radiation, Prototyping, In vivo imaging, Image acquisition

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PROCEEDINGS ARTICLE | February 17, 2011

Translating ultraviolet autofluorescence microscopy toward clinical endomicroscopy

Proc. SPIE. 7895, Optical Biopsy IX

KEYWORDS: Atrial fibrillation, Visualization, Tissues, Imaging systems, Ultraviolet radiation, Microscopy, Image acquisition, Image filtering, Tissue optics, Esophagus

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SPIE Conference Volume | February 16, 2011

Optical Biopsy IX

PROCEEDINGS ARTICLE | January 3, 2011

Clinical translation of ultraviolet autofluorescence microscopy towards endomicroscopy for early detection of cancer

Proc. SPIE. 7990, Optical Sensors and Biophotonics II

KEYWORDS: Endoscopy, Microscopes, Atrial fibrillation, Tissues, Imaging systems, Ultraviolet radiation, Microscopy, Image filtering, Endomicroscopy, Tissue optics

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SPIE Journal Paper | January 1, 2011

Time-resolved microscope system to image material response following localized laser energy deposition: exit surface damage in fused silica as a case example

Raman, Rajesh , Negres, Raluca , Demos, Stavros

OE Vol. 50 Issue 01

KEYWORDS: Imaging systems, Particles, Microscopes, Polarization, Silica, Laser energy, Laser beam diagnostics, Image processing, Laser induced damage, Temporal resolution

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PROCEEDINGS ARTICLE | December 1, 2010

Imaging the early material response associated with exit surface damage in fused silica

Proc. SPIE. 7842, Laser-Induced Damage in Optical Materials: 2010

KEYWORDS: Microscopes, Silica, Polarization, Imaging systems, Temporal resolution, Picosecond phenomena, Spatial resolution, Laser beam diagnostics, Pulsed laser operation, Laser systems engineering

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SPIE Journal Paper | July 1, 2010

Direct curvature correction for noncontact imaging modalities applied to multispectral imaging

Kainerstorfer, Jana , Amyot, Franck , Ehler, Martin , Hassan, Moinuddin , Demos, Stavros , Chernomordik, Victor , Hitzenberger, Christoph , Gandjbakhche, Amir , Casale, Giuseppe

JBO Vol. 15 Issue 04

KEYWORDS: Multispectral imaging, Blood, In vivo imaging, Spatial frequencies, Optical properties, Numerical simulations, Chromophores, Skin, Absorption, Optical imaging

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SPIE Journal Paper | July 1, 2010

Principal component model of multispectral data for near real-time skin chromophore mapping

Kainerstorfer, Jana , Ehler, Martin , Amyot, Franck , Hassan, Moinuddin , Demos, Stavros , Chernomordik, Victor , Hitzenberger, Christoph , Gandjbakhche, Amir , Riley, Jason

JBO Vol. 15 Issue 04

KEYWORDS: Blood, Principal component analysis, Skin, Data modeling, Chromophores, Multispectral imaging, Associative arrays, Absorption, RGB color model, Biological research

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SPIE Conference Volume | February 25, 2010

Optical Biopsy VII

PROCEEDINGS ARTICLE | February 23, 2010

Optical spectroscopy approach for the predictive assessment of kidney functional recovery following ischemic injury

Proc. SPIE. 7561, Optical Biopsy VII

KEYWORDS: Injuries, Ischemia, Atrial fibrillation, Tissues, Scattering, Blood, Light scattering, Optical spectroscopy, Kidney, Tissue optics

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PROCEEDINGS ARTICLE | February 18, 2010

Time-resolved imaging of material response following laser-induced breakdown in the bulk and surface of fused silica

Proc. SPIE. 7581, High Energy/Average Power Lasers and Intense Beam Applications IV

KEYWORDS: Microscopes, Silica, Polarization, Backscatter, Imaging systems, Image processing, Laser induced damage, Particles, Spatial resolution, Absorption

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PROCEEDINGS ARTICLE | February 11, 2010

Visualization of epithelial morphology using autofluorescence microscopy under ultraviolet excitation

Proc. SPIE. 7561, Optical Biopsy VII

KEYWORDS: Atrial fibrillation, Visualization, Tissues, Spectroscopy, Ultraviolet radiation, Microscopy, Imaging spectroscopy, Image filtering, Tissue optics, Prototyping

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PROCEEDINGS ARTICLE | December 31, 2009

Imaging system to measure kinetics of material cluster ejection during exit-surface damage initiation and growth in fused silica

Proc. SPIE. 7504, Laser-Induced Damage in Optical Materials: 2009

KEYWORDS: Microscopes, Silica, Polarization, Backscatter, Imaging systems, Image processing, Particles, Spatial resolution, Laser beam diagnostics, Pulsed laser operation

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PROCEEDINGS ARTICLE | July 10, 2009

Quantitative assessment of ischemia and reactive hyperemia of the dermal layers using multi - spectral imaging on the human arm

Proc. SPIE. 7369, Diffuse Optical Imaging II

KEYWORDS: Veins, Ischemia, Tissues, Imaging systems, Blood, Skin, Imaging spectroscopy, Oxygen, Chromophores, Reconstruction algorithms

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SPIE Journal Paper | March 1, 2009

Evaluation of the contribution of the renal capsule and cortex to kidney autofluorescence intensity under ultraviolet excitation

Raman, Rajesh , Pivetti, Christopher , Rubenchik, Alexander , Matthews, Dennis , Troppmann, Christoph , Demos, Stavros

JBO Vol. 14 Issue 02

KEYWORDS: Kidney, Atrial fibrillation, Tissues, Ultraviolet radiation, Signal attenuation, Luminescence, Microscopy, Mode conditioning cables, Blood, Mathematical modeling

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PROCEEDINGS ARTICLE | December 30, 2008

Interactions between x-ray induced transient defects and pre-existing damage precursors in DKDP crystals

Proc. SPIE. 7132, Laser-Induced Damage in Optical Materials: 2008

KEYWORDS: Laser induced damage, Crystals, X-rays, Copper, Laser applications, Laser damage threshold, Laser crystals, Rhodium, Crystallography, Laser systems engineering

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PROCEEDINGS ARTICLE | December 30, 2008

Time-resolved imaging of material response during laser-induced bulk damage in SiO2

Proc. SPIE. 7132, Laser-Induced Damage in Optical Materials: 2008

KEYWORDS: Silica, Laser induced damage, Ions, Wave propagation, Image enhancement, Zoom lenses, Laser beam diagnostics, Bulk lasers, Current controlled current source, Absorption

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PROCEEDINGS ARTICLE | March 11, 2008

Evaluation of optical imaging and spectroscopy approaches for cardiac tissue depth assessment

Proc. SPIE. 6864, Biomedical Applications of Light Scattering II

KEYWORDS: Mathematical modeling, Optical imaging, Near infrared, Polarization, Tissues, Spectroscopy, Light scattering, Imaging spectroscopy, Optical spectroscopy, Tissue optics

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PROCEEDINGS ARTICLE | February 20, 2008

Autofluorescence dynamics during reperfusion following long-term renal ischemia in a rat model

Proc. SPIE. 6853, Biomedical Optical Spectroscopy

KEYWORDS: Injuries, Ischemia, Optical properties, Tissues, Light scattering, Oxygen, Kidney, In vivo imaging, Tissue optics, Natural surfaces

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PROCEEDINGS ARTICLE | December 20, 2007

High-resolution 3D imaging of surface damage sites in fused silica with optical coherence tomography

Proc. SPIE. 6720, Laser-Induced Damage in Optical Materials: 2007

KEYWORDS: Microscopes, Silica, Lenses, Calibration, Optical coherence tomography, Laser induced damage, Microscopy, 3D metrology, Gas lasers, National Ignition Facility

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PROCEEDINGS ARTICLE | December 20, 2007

Pump and probe damage testing for investigation of transient material modifications associated with laser damage in optical materials

Proc. SPIE. 6720, Laser-Induced Damage in Optical Materials: 2007

KEYWORDS: Silica, Laser induced damage, Dielectrics, Nd:YAG lasers, Objectives, Q switched lasers, Helium neon lasers, Laser beam diagnostics, Pulsed laser operation, Absorption

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PROCEEDINGS ARTICLE | December 18, 2007

Does complex absorption behavior leading to conditioning and damage in KDP/DKDP reflect the electronic structure of initiators?

Proc. SPIE. 6720, Laser-Induced Damage in Optical Materials: 2007

KEYWORDS: Databases, Laser induced damage, Laser energy, Photons, Crystals, Electrons, Laser damage threshold, Laser crystals, Frequency conversion, Absorption

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SPIE Journal Paper | September 1, 2007

Using noninvasive multispectral imaging to quantitatively assess tissue vasculature

Vogel, Abby , Chernomordik, Victor , Riley, Jason , Hassan, Moinuddin , Amyot, Franck , Dasgeb, Bahar , Demos, Stavros , Pursley, Randy , Little, Richard , Yarchoan, Robert , Tao, Yang , Gandjbakhche, Amir

JBO Vol. 12 Issue 05

KEYWORDS: Blood, Tissues, Skin, Multispectral imaging, Tissue optics, Calibration, Near infrared spectroscopy, Absorption, Therapeutics, Doppler effect

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PROCEEDINGS ARTICLE | February 19, 2007

In-vivo quantification of autofluorescence dynamics during renal ischemia and reperfusion under dual-UV excitation

Proc. SPIE. 6441, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues V

KEYWORDS: Injuries, Ischemia, Tissues, Surgery, Luminescence, Oxygen, Kidney, In vivo imaging, Tissue optics, Mode conditioning cables

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PROCEEDINGS ARTICLE | January 15, 2007

Thermal imaging investigation of modified fused silica at surface damage sites for understanding the underlying mechanisms of damage growth

Proc. SPIE. 6403, Laser-Induced Damage in Optical Materials: 2006

KEYWORDS: Thermography, Continuous wave operation, Silica, Laser induced damage, Ultraviolet radiation, Luminescence, Diffusion, Thermal modeling, Temperature metrology, Absorption

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PROCEEDINGS ARTICLE | January 15, 2007

An expedited approach to evaluate the importance of different crystal growth parameters on laser damage performance in KDP and DKDP

Proc. SPIE. 6403, Laser-Induced Damage in Optical Materials: 2006

KEYWORDS: Prisms, Nanoparticles, Laser induced damage, Ultraviolet radiation, Crystals, Light scattering, Resistance, Raw materials, Laser crystals, Absorption

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SPIE Journal Paper | October 1, 2006

Differentiation of defect populations responsible for bulk laser-induced damage in potassium dihydrogen phosphate crystals

DeMange, Paul , Negres, Raluca , Radousky, Harry , Demos, Stavros

OE Vol. 45 Issue 10

KEYWORDS: Scattering, Crystals, Laser induced damage, Potassium, Laser crystals, Light scattering, Optical engineering, Pulsed laser operation, Microscopes, Physics

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PROCEEDINGS ARTICLE | February 22, 2006

In vivo spectroscopic monitoring of renal ischemia and reperfusion in a rat model

Proc. SPIE. 6091, Optical Biopsy VI

KEYWORDS: Injuries, Ischemia, Tissues, Blood, Spectroscopy, Light scattering, Optical spectroscopy, Image filtering, Kidney, In vivo imaging

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PROCEEDINGS ARTICLE | February 22, 2006

Real-time imaging of tissue microstructures using intrinsic optical signatures

Proc. SPIE. 6091, Optical Biopsy VI

KEYWORDS: Confocal microscopy, Microscopes, Real time imaging, Tissues, Light scattering, Image acquisition, Objectives, Image filtering, Image enhancement, Tissue optics

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PROCEEDINGS ARTICLE | February 10, 2006

Laser-induced defect reactions governing damage performance in KDP and DKDP crystals

Proc. SPIE. 6103, Nonlinear Frequency Generation and Conversion: Materials, Devices, and Applications V

KEYWORDS: Modulation, Laser induced damage, Crystals, Physics, Laser damage threshold, Laser crystals, Frequency conversion, Bulk lasers, Laser systems engineering, Absorption

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PROCEEDINGS ARTICLE | February 7, 2006

A multi-dimensional investigation of laser conditioning in KDP and DKDP crystals

Proc. SPIE. 5991, Laser-Induced Damage in Optical Materials: 2005

KEYWORDS: Eye, Laser induced damage, Crystals, Physics, CCD cameras, Solids, Laser damage threshold, Laser crystals, Laser optics, Laser systems engineering

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PROCEEDINGS ARTICLE | February 7, 2006

Different precursor populations revealed by microscopic studies of bulk damage in KDP and DKDP crystals

Proc. SPIE. 5991, Laser-Induced Damage in Optical Materials: 2005

KEYWORDS: Microscopes, Continuous wave operation, Scattering, Laser induced damage, Crystals, Light scattering, Image resolution, Pixel resolution, Helium neon lasers, Crystallography

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PROCEEDINGS ARTICLE | February 7, 2006

Laser-induced damage in DKDP crystals under simultaneous exposure to laser harmonics

Proc. SPIE. 5991, Laser-Induced Damage in Optical Materials: 2005

KEYWORDS: Laser induced damage, Crystals, Nd:YAG lasers, Objectives, Laser damage threshold, Laser crystals, Harmonic generation, Frequency conversion, Nonlinear crystals, Laser systems engineering

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SPIE Journal Paper | July 1, 2005

Real-time assessment of in vivo renal ischemia using laser autofluorescence imaging

Fitzgerald, Jason , Michalopoulou, Andromachi , Pivetti, Christopher , Raman, Rajesh , Troppmann, Christoph , Demos, Stavros

JBO Vol. 10 Issue 04

KEYWORDS: Ischemia, Kidney, Injuries, Spectroscopy, In vivo imaging, Control systems, Absorption, Light scattering, Optical spectroscopy, Tissues

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PROCEEDINGS ARTICLE | March 23, 2005

Nonlinear behavior of laser-induced damage in KDP and DKDP under multiwavelength irradiation

Proc. SPIE. 5710, Nonlinear Frequency Generation and Conversion: Materials, Devices, and Applications IV

KEYWORDS: Potassium, Imaging systems, Laser induced damage, Crystals, Laser development, Nd:YAG lasers, Laser crystals, Analog electronics, Frequency conversion, Laser systems engineering

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PROCEEDINGS ARTICLE | February 21, 2005

Stoichiometric changes to KH2PO4 during laser-induced breakdown

Proc. SPIE. 5647, Laser-Induced Damage in Optical Materials: 2004

KEYWORDS: Spectroscopy, Laser induced damage, High power lasers, Luminescence, Crystals, Laser scattering, Raman spectroscopy, Raman scattering, Laser crystals, Crystallography

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PROCEEDINGS ARTICLE | February 21, 2005

A new damage testing system for detailed evaluation of damage behavior of bulk KDP and DKDP

Proc. SPIE. 5647, Laser-Induced Damage in Optical Materials: 2004

KEYWORDS: Microscopes, Laser induced damage, Crystals, Light scattering, Laser development, Laser scattering, Optical testing, CCD cameras, Laser damage threshold, Laser crystals

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PROCEEDINGS ARTICLE | February 21, 2005

The nature of emission from optical breakdown induced by pulses of fs and ns duration

Proc. SPIE. 5647, Laser-Induced Damage in Optical Materials: 2004

KEYWORDS: Second-harmonic generation, Femtosecond phenomena, Chromium, Laser induced fluorescence, Time metrology, Black bodies, Ionization, Harmonic generation, Pulsed laser operation, Plasma

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PROCEEDINGS ARTICLE | July 13, 2004

Spectroscopic monitoring of kidney tissue ischemic injury

Proc. SPIE. 5326, Optical Biopsy V

KEYWORDS: Optical filters, Injuries, Ischemia, Spectroscopy, Light scattering, Transplantation, Optical spectroscopy, Image filtering, Kidney, Tissue optics

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SPIE Journal Paper | July 1, 2004

Spectroscopic detection of bladder cancer using near-infrared imaging techniques

Demos, Stavros , Gandour-Edwards, Regina , Ramsamooj, Rajen , White, Ralph de Vere

JBO Vol. 9 Issue 04

KEYWORDS: Tissues, Cancer, Tumors, Bladder cancer, Bladder, Tissue optics, Near infrared, Spectroscopy, Imaging spectroscopy, Light scattering

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PROCEEDINGS ARTICLE | June 14, 2004

Challenges for the development of clinically useful fluorescing diagnostic contrast agents for optical imaging: a radiologist's perspective

Proc. SPIE. 5329, Genetically Engineered and Optical Probes for Biomedical Applications II

KEYWORDS: Optical imaging, Tumors, Tissues, Imaging systems, Blood, Magnetic resonance imaging, Diagnostics, Indocyanine green, In vivo imaging, Plasma

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PROCEEDINGS ARTICLE | June 14, 2004

Microscopic characterization of laser-induced damage performance of large-size KDP and DKDP nonlinear crystals

Proc. SPIE. 5337, Nonlinear Frequency Generation and Conversion: Materials, Devices, and Applications III

KEYWORDS: Optical components, Laser induced damage, Crystals, Light scattering, CCD cameras, Laser damage threshold, Laser crystals, Frequency conversion, Nonlinear crystals, Laser systems engineering

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SPIE Journal Paper | May 1, 2004

Near-infrared autofluorescence imaging for detection of cancer

Demos, Stavros , Gandour-Edwards, Regina , Ramsamooj, Rajen , White, Ralph de Vere

JBO Vol. 9 Issue 03

KEYWORDS: Tissues, Cancer, Near infrared, Tumors, Kidney, Liver, Auto-fluorescence imaging, Luminescence, Bladder, Polarization

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PROCEEDINGS ARTICLE | December 12, 2003

Hyperspectral imaging of cells: toward real-time pathological assessment

Proc. SPIE. 5201, Photonic Devices and Algorithms for Computing V

KEYWORDS: Microscopes, Polarization, Tissues, Imaging systems, Microscopy, Luminescence, Light scattering, Imaging spectroscopy, In vivo imaging, Tissue optics

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PROCEEDINGS ARTICLE | October 8, 2003

In vivo NIR autofluorescence of rat mammary tumors discriminates pathological malignancy

Proc. SPIE. 5141, Diagnostic Optical Spectroscopy in Biomedicine II

KEYWORDS: Optical imaging, Near infrared, Tumor growth modeling, Cancer, Breast cancer, Tumors, Visualization, Tissues, Luminescence, Signal detection

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PROCEEDINGS ARTICLE | September 12, 2003

Spectroscopic imaging of bladder cancer

Proc. SPIE. 4949, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XIII

KEYWORDS: Near infrared, Cancer, Tumors, Tissues, Spectroscopy, Light scattering, Imaging spectroscopy, Bladder, Tissue optics, Bladder cancer

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PROCEEDINGS ARTICLE | May 30, 2003

Evolution of bulk damage initiation in DKDP crystals

Proc. SPIE. 4932, Laser-Induced Damage in Optical Materials: 2002 and 7th International Workshop on Laser Beam and Optics Characterization

KEYWORDS: Laser induced damage, Crystals, Laser scattering, Laser beam propagation, Laser damage threshold, Laser crystals, Pulsed laser operation, Plasma, Laser systems engineering, Fusion energy

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PROCEEDINGS ARTICLE | May 30, 2003

Experimental study of wavelength-dependent damage threshold in DKDP

Proc. SPIE. 4932, Laser-Induced Damage in Optical Materials: 2002 and 7th International Workshop on Laser Beam and Optics Characterization

KEYWORDS: Potassium, Optical parametric oscillators, Data modeling, Laser induced damage, Particles, Electrons, Laser damage threshold, Laser optics, Pulsed laser operation, Absorption

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PROCEEDINGS ARTICLE | May 1, 2002

Tissue imaging for cancer detection using NIR autofluorescence

Proc. SPIE. 4613, Optical Biopsy IV

KEYWORDS: Near infrared, Cancer, Tumors, Polarization, Tissues, Luminescence, Light scattering, Kidney, Tissue optics, Laser tissue interaction

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PROCEEDINGS ARTICLE | April 9, 2002

Investigation of fluorescence microscopy as a tool for noninvasive detection and imaging of damage precursors at 351 nm

Proc. SPIE. 4679, Laser-Induced Damage in Optical Materials: 2001

KEYWORDS: Polishing, Contamination, Laser induced damage, Microscopy, Luminescence, Crystals, Light scattering, Laser damage threshold, Surface finishing, Plasma

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PROCEEDINGS ARTICLE | April 9, 2002

Performance of bare and sol-gel-coated DKDP crystal surfaces exposed to multiple 351-nm laser pulses in vacuum and air

Proc. SPIE. 4679, Laser-Induced Damage in Optical Materials: 2001

KEYWORDS: Carbon, Silica, Reflection, Luminescence, Crystals, Nitrogen, Reflectivity, Laser crystals, Information operations, Absorption

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PROCEEDINGS ARTICLE | April 9, 2002

Improving 351-nm damage performance of large-aperture fused silica and DKDP optics

Proc. SPIE. 4679, Laser-Induced Damage in Optical Materials: 2001

KEYWORDS: Polishing, Silica, Etching, Laser induced damage, Crystals, Light scattering, National Ignition Facility, Surface finishing, UV optics, Absorption

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PROCEEDINGS ARTICLE | April 9, 2002

Time-resolved spectroscopic investigation of emission observed during damage in the bulk of fused silica and DKDP crystals

Proc. SPIE. 4679, Laser-Induced Damage in Optical Materials: 2001

KEYWORDS: Mirrors, Silica, Spectroscopy, Laser induced damage, Crystals, Black bodies, Time resolved spectroscopy, Pulsed laser operation, Off axis mirrors, Plasma

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PROCEEDINGS ARTICLE | April 16, 2001

Endoscopic subsurface imaging in tissues

Proc. SPIE. 4261, Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing VIII

KEYWORDS: Breast, Endoscopy, Cancer, Polarization, Tissues, Imaging systems, Photons, Endoscopes, Bladder, Natural surfaces

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PROCEEDINGS ARTICLE | April 12, 2001

Chemical etch effects on laser-induced surface damage growth in fused silica

Proc. SPIE. 4347, Laser-Induced Damage in Optical Materials: 2000

KEYWORDS: Silica, Etching, Laser induced damage, Ultraviolet radiation, Luminescence, Oxygen, Scanning electron microscopy, Wet etching, Hydrogen fluoride lasers, HF etching

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PROCEEDINGS ARTICLE | April 12, 2001

Nature of damage in fused silica induced by high-fluence 3-omega 355-nm laser pulses, a multiscale morphology microstructure, and defect chemistry study

Proc. SPIE. 4347, Laser-Induced Damage in Optical Materials: 2000

KEYWORDS: Polishing, Silica, Laser induced damage, X-rays, Silicon, Chemistry, Scanning electron microscopy, Transmission electron microscopy, Tomography, Surface finishing

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PROCEEDINGS ARTICLE | April 12, 2001

Mechanisms to explain damage growth in optical materials

Proc. SPIE. 4347, Laser-Induced Damage in Optical Materials: 2000

KEYWORDS: Silica, Image processing, Laser induced damage, Luminescence, Light scattering, Laser scattering, Laser irradiation, Ionization, Pulsed laser operation, Plasma

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PROCEEDINGS ARTICLE | October 26, 2000

Effect of vacuum on the occurrence of UV-induced surface photoluminescence, transmission loss, and catastrophic surface damage

Proc. SPIE. 4134, Photonics for Space Environments VII

KEYWORDS: Visible radiation, Silica, Laser induced damage, Ultraviolet radiation, Luminescence, Reflectivity, CCD cameras, Transmittance, Sol-gels, Absorption

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PROCEEDINGS ARTICLE | October 25, 2000

Properties of modified silica detected within laser-induced damage sites

Proc. SPIE. 4102, Inorganic Optical Materials II

KEYWORDS: Silica, Laser induced damage, Luminescence, Silicon, 3D modeling, Oxygen, Raman spectroscopy, Raman scattering, Surface finishing, Absorption

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PROCEEDINGS ARTICLE | June 7, 2000

Spectroscopic investigation of SiO2 surfaces of optical materials for high-power lasers

Proc. SPIE. 3933, Laser Applications in Microelectronic and Optoelectronic Manufacturing V

KEYWORDS: Polishing, Silica, Spectroscopy, Laser induced damage, High power lasers, Luminescence, Laser applications, Raman spectroscopy, Raman scattering, Surface finishing

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PROCEEDINGS ARTICLE | April 19, 2000

Instrumentation for subsurface imaging in a clinical environment

Proc. SPIE. 3917, Optical Biopsy III

KEYWORDS: Endoscopy, Cancer, Tumors, Polarization, Tissues, Imaging systems, Polarizers, Endoscopes, Tissue optics, Natural surfaces

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PROCEEDINGS ARTICLE | March 24, 2000

Optical spectroscopy study of transparent noncarious human dentin and dentin-enamel junction

Proc. SPIE. 3910, Lasers in Dentistry VI

KEYWORDS: Optical filters, Minerals, Teeth, Tissues, Spectroscopy, Microscopy, Luminescence, Fluorescence spectroscopy, Optical spectroscopy, Zoom lenses

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PROCEEDINGS ARTICLE | March 3, 2000

Laser-induced material modification in the bulk KDP crystals

Proc. SPIE. 3902, Laser-Induced Damage in Optical Materials: 1999

KEYWORDS: Imaging systems, Laser induced damage, High power lasers, Luminescence, Crystals, Light scattering, Laser damage threshold, Laser crystals, Surface finishing, Plasma

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PROCEEDINGS ARTICLE | March 3, 2000

Time-resolved studies of laser damage processes in DKDP crystals

Proc. SPIE. 3902, Laser-Induced Damage in Optical Materials: 1999

KEYWORDS: Birefringence, Laser induced damage, Luminescence, Crystals, Laser processing, Polarizers, Wave propagation, Solids, Laser crystals, Crystallography

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PROCEEDINGS ARTICLE | March 3, 2000

Luminescence investigation of SiO2 surfaces damaged by 0.35-nm laser illumination

Proc. SPIE. 3902, Laser-Induced Damage in Optical Materials: 1999

KEYWORDS: Polishing, Silica, Laser induced damage, Particles, Luminescence, Silicon, Oxygen, Surface finishing, Plasma, Absorption

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PROCEEDINGS ARTICLE | July 15, 1999

Subsurface imaging using the spectral polarization difference technique and NIR illumination

Proc. SPIE. 3597, Optical Tomography and Spectroscopy of Tissue III

KEYWORDS: Breast, Near infrared, Optical filters, Light sources, Veins, Polarization, Tissues, Photons, Light scattering, Natural surfaces

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PROCEEDINGS ARTICLE | May 26, 1999

Steady-state and transient defect populations in KH2PO4 subsequent to high-fluence laser irradiation

Proc. SPIE. 3610, Laser Material Crystal Growth and Nonlinear Materials and Devices

KEYWORDS: High power lasers, Luminescence, Crystals, Ions, Raman spectroscopy, Laser irradiation, Raman scattering, Laser crystals, Laser beam diagnostics, Absorption

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PROCEEDINGS ARTICLE | April 7, 1999

Observation of photoexcited emission clusters in the bulk of KDP and laser conditioning under 355-nm irradiation

Proc. SPIE. 3578, Laser-Induced Damage in Optical Materials: 1998

KEYWORDS: Imaging systems, Laser induced damage, High power lasers, Luminescence, Crystals, Ions, Laser irradiation, Laser crystals, Active optics, Absorption

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PROCEEDINGS ARTICLE | May 1, 1998

Miniature uncooled infrared sensitive detectors for in-vivo biomedical applications

Proc. SPIE. 3253, Biomedical Sensing and Imaging Technologies

KEYWORDS: Infrared detectors, Thermography, Infrared sensors, Infrared imaging, Mirrors, Modulation, Sensors, Infrared radiation, In vivo imaging, Absorption

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PROCEEDINGS ARTICLE | April 20, 1998

Temperature and spectral investigation of bulk KDP below damage using 355-nm laser irradiation

Proc. SPIE. 3244, Laser-Induced Damage in Optical Materials: 1997

KEYWORDS: Near infrared, Visible radiation, Crystals, Raman spectroscopy, Laser irradiation, Laser crystals, Temperature metrology, High temperature raman spectroscopy

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PROCEEDINGS ARTICLE | April 16, 1998

Far-red and NIR emissions from tissues

Proc. SPIE. 3250, Optical Biopsy II

KEYWORDS: Breast, Near infrared, Optical filters, Polarization, Tissues, Spectroscopy, Laser scattering, Linear filtering, Raman scattering, Picosecond phenomena

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PROCEEDINGS ARTICLE | August 18, 1997

Time-gated images of calcification regions in turbid media

Proc. SPIE. 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II

KEYWORDS: Breast, Cancer, Breast cancer, Tissues, Imaging systems, Scattering, Scattering media, Particles, Calcium, Picosecond phenomena

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PROCEEDINGS ARTICLE | August 18, 1997

Differential spectral polarization imaging

Proc. SPIE. 2979, Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II

KEYWORDS: Optical imaging, Polarization, Backscatter, Tissues, Imaging systems, Scattering, Photons, Light scattering, Natural surfaces, Absorption

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PROCEEDINGS ARTICLE | June 16, 1997

Raman spectra of biomedical samples using optical fiber probes

Proc. SPIE. 2976, Biomedical Sensing, Imaging, and Tracking Technologies II

KEYWORDS: Optical fibers, Optical filters, Silica, Fiber optics, Tissues, Luminescence, Fourier transforms, Fiber lasers, Raman spectroscopy, Raman scattering

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PROCEEDINGS ARTICLE | November 8, 1996

Temporal polarization preservation in human breast tissue: a method for optical imaging

Proc. SPIE. 2965, ALT '96 International Symposium on Laser Methods for Biomedical Applications

KEYWORDS: Optical imaging, Breast, Cancer, Tumors, Polarization, Tissues, Picosecond phenomena, Tissue optics, Laser tissue interaction, Light wave propagation

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