Prof. Steven L. Jacques
Professor/SPIE Fellow at Tufts Univ
SPIE Involvement:
Fellow status | Conference Program Committee | Conference Chair | Track Chair | Author | Instructor
Area of Expertise:
tissue optics , laser-tissue interactions
Profile Summary

Steven L. Jacques, Ph.D., received a B.S. degree in Biology at M.I.T., and an M.S. degree in Electrical Engineering and Computer Science and a Ph.D. degree in Biophysics and Medical Physics from the University of California-Berkeley (1984), where he used dielectric microwave measurements to explore the in vivo distribution of water in the stratum corneum of human skin.
His postdoctoral work was at the Wellman Center for Photomedicine at Massachusetts General Hospital, rising to the position of Lecturer in Dermatology/Bioengineering, Harvard Medical School. His team developed the use of Monte Carlo computer simulations to study optical transport in biological tissues, which is now widely used in the field of biophotonics.
In 1988, he joined the University of Texas M. D. Anderson Cancer as an Assistant Professor of Urology/Biophysics and established a laboratory developing novel laser and optical methods for medicine, later achieving a tenured position as Associate Professor. He developed a hand-held spectrometer and the analysis software to noninvasively measure hyperbilirubinemia in newborns. This device was patented, licensed, and FDA approved to replace heel stick tests, and is now in practice in neonatal care. As of 2009, over 20 million newborns have been tested with the device.
In 1996, he joined the Oregon Health and Science University in Portland where he now serves as Professor of Dermatology and Biomedical Engineering. His work continues on developing novel uses of optical technologies for both therapy and diagnosis. Currently, he has developed a hand-held polarized light camera to visualize skin cancer margins and guide surgical excision, now in clinical trials. He has developed in vivo sub-nm measurements of vibration of the cochlear membrane of the inner ear in animal models. He is developing novel microscopes that are sensitive to the ultrastructure of cells and tissues.
Publications (272)

SPIE Journal Paper | December 5, 2018
JBO Vol. 23 Issue 12
KEYWORDS: Tissues, Light emitting diodes, Imaging systems, Skin, Multispectral imaging, Cameras, Scattering, Monte Carlo methods, Spectroscopy, Blood

SPIE Journal Paper | January 26, 2018
JBO Vol. 23 Issue 07
KEYWORDS: Light emitting diodes, Absorption, Optical spectroscopy, Optical properties, Tissue optics, Blood, Reflectivity, Condition numbers, Error analysis, Tissues

SPIE Journal Paper | November 6, 2017
JBO Vol. 22 Issue 11
KEYWORDS: Skin, Optical character recognition, Blood, Oxygen, Tissue optics, In vivo imaging, Blood circulation, Reflectivity, Tissues, Optical fibers

SPIE Journal Paper | May 22, 2017
JBO Vol. 22 Issue 05
KEYWORDS: Reflectivity, Sensors, Scattering, Tissue optics, Photons, Light scattering, Monte Carlo methods, Optical properties, Sodium, Backscatter

Proc. SPIE. 10055, Optics and Biophotonics in Low-Resource Settings III
KEYWORDS: Light sources, Light emitting diodes, Data modeling, Tissues, Imaging systems, Cameras, Light scattering, Multispectral imaging, Image transmission, Tissue optics