In this study, we demonstrate the potential manufacturing method and application of 2D WSe2-based field-effect transistors (2D-FETs) as a promising biosensor for the selective and rapid detection of a pathogen such as SARS-CoV-2 in vitro. The sensors are manufactured by first synthesizing 2D material on Si/SiO2 substrates, followed by photolithography processes to form the FET devices. Then, the surface of 2D material WSe2 has been functionalized with a specific antibody to selectively detect the SARS-CoV-2 spike protein. The TMDC-based 2D-FETs can potentially serve as sensitive and selective biosensors for the rapid detection of infectious diseases.
The scalable and patterned growth of two-dimensional (2D) quantum materials is essential for wafer-scale device integration in order to transition their exciting properties and performance from lab to fab. However, the current gas-phase synthesis methods are incompatible with conventional patterning technologies (e.g., lithography) or require extensive top-down processing steps (e.g., etching) to create the desired device structures on the substrates. In this talk, I will describe some of the laser-based approaches we are undertaking to control the synthesis and integration of various 2D materials. I will particularly highlight our recently developed condensed phase growth approach compatible with direct laser writing as well as the conventional lithography and device integration technologies.
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