It is well known that cells respond to structured surface cues that are on the micro/nanometer scale. Tissue engineering
and bio-fouling fields have utilized the semiconductor device fabrication processes to make micro- and nanometer
patterned surfaces to study animal cell tissue formation and to prevent algae attachment on marine surfaces respectively.
In this paper we describe the use of micro-structured surfaces to study the attachment and growth of algal films. This
paper gives an overview of how micro-structured surfaces are made for this purpose, how they are incorporated into a
photo bioreactor and how this patterning influences the growth of an algal biofilm. Our results suggest that surface
patterning with deeper V-groove patterns that are of the same size scale as the algal species has resulted in higher
biomass productivity giving them a chance to embed and attach on the slope and flat surfaces whereas shallower size
grooves and completely flat surfaces did not show this trend.