Dr. Thomas D. O'Sullivan
Associate Professor
SPIE Involvement:
Author | Editor | Leadership Workshop Facilitator
Area of Expertise:
Biomedical Optics , Cancer Imaging , Lasers , Implantable optical sensors , Diffuse optical spectroscopy
Profile Summary

Dr. Thomas O'Sullivan is an associate professor in the Department of Electrical Engineering at the University of Notre Dame. Prior to that he was the Director of the Diffuse Optical Spectroscopy and Imaging Laboratory at the Beckman Laser Institute at the University of California, Irvine and a U.S. Department of Defense Breast Cancer Research Program Postdoctoral Fellow. He received the B.S. degree in Electrical Engineering from Northwestern University in 2005 and the M.S. and Ph.D. in Electrical Engineering from Stanford University in 2007 and 2011, respectively. Dr. O'Sullivan is engaged in translational biomedical research based upon the development and application of deep tissue optical imaging and sensing. In particular, Dr. O'Sullivan’s lab is advancing diffuse optical spectroscopy and imaging (DOSI), which allows for contrast-free quantitative measurements of tissue architecture and metabolic function. This work, while relevant to many diseases, is presently focused on applications in breast cancer including risk assessment, screening, differential diagnosis, and predicting individual response to chemotherapy treatment. Dr. O'Sullivan has co-founded one company in this area (NearWave Corp.) and holds several patents on DOSI-related technologies. In addition to his research, Dr. O’Sullivan is passionate about community outreach, has served the optics and photonics community as a senior member of OSA and SPIE, and is currently an associate editor for Biomedical Optics Express.
Publications (40)

Proceedings Article | 13 March 2024 Presentation
Roy Stillwell, Adam Longoria, Eric Sheeder, Karla Gonzalez, Nicholas Ross, Thomas O'Sullivan
Proceedings Volume PC12827, PC128270A (2024) https://doi.org/10.1117/12.3003850
KEYWORDS: Optical properties, Near infrared spectroscopy, Imaging systems, Laser frequency, Tissues, Data acquisition, Tumors, Tissue optics, Tablets, System on a chip

Proceedings Article | 13 March 2024 Poster + Paper
Nathan Campeau, Alicia Wei, Anuj Gajjar, Ola Abdalsalam, Thomas O'Sullivan
Proceedings Volume 12827, 1282707 (2024) https://doi.org/10.1117/12.3003431
KEYWORDS: 3D modeling, Monte Carlo methods, Tissues, Systems modeling, Diffusion, Optical sensors, Sensors, Ray tracing, Design

Proceedings Article | 17 March 2023 Presentation
Proceedings Volume PC12430, PC1243012 (2023) https://doi.org/10.1117/12.2649023
KEYWORDS: Tissue optics, Imaging spectroscopy, Diffuse optical spectroscopy, Optical imaging, Near infrared spectroscopy, Diffuse optical imaging, Scattering, Optical testing, Technologies and applications, Photonics

Proceedings Article | 7 March 2023 Presentation + Paper
Ola Abdalsalam, Nicholas Ross, Guy Perkins, Robin Dale, Hamid Dehghani, Thomas O'Sullivan, Silvina L. Ferradal
Proceedings Volume 12376, 1237607 (2023) https://doi.org/10.1117/12.2650970
KEYWORDS: Optical properties, Tissues, Absorption, Error analysis, Modulation frequency, Near infrared spectroscopy, Signal detection, Source detector separation, Tissue optics, Scattering

Proceedings Article | 7 March 2023 Presentation + Paper
Proceedings Volume 12376, 1237606 (2023) https://doi.org/10.1117/12.2651676
KEYWORDS: Tomography, Near infrared spectroscopy, Tissues, Signal attenuation, Optical properties, Tissue optics, Modulation frequency, Image resolution, Finite element methods, Scattering

Showing 5 of 40 publications
Proceedings Volume Editor (2)

SPIE Conference Volume | 30 August 2023

SPIE Conference Volume | 9 December 2021

Conference Committee Involvement (6)
Optical Tomography and Spectroscopy of Tissue XVI
25 January 2025 | San Francisco, California, United States
Diffuse Optical Spectroscopy and Imaging
25 June 2023 | Munich, Germany
Optical Tomography and Spectroscopy of Tissue XV
30 January 2023 | San Francisco, California, United States
Diffuse Optical Spectroscopy and Imaging VIII
20 June 2021 | Online Only, Germany
Optical Tomography and Spectroscopy of Tissue XIV
6 March 2021 | Online Only, California, United States
Showing 5 of 6 Conference Committees
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