Dr. Tobias Meyer-Zedler Profile

Dr. Tobias Meyer-Zedler

at Leibniz-Institut fur Photonische Technologien eV

SPIE Involvement:

Author

Publications (27)

Proceedings Article | 13 March 2024 Presentation

Rigid endomicroscopic system for cancer diagnosis and tissue removal

Matteo Calvarese, Hyeonsoo Bae, Chenting Lai, Karl Reichwald, Tobias Meyer-Zedler, Bernhard Messerschmidt, Ayman Bali, David Pertzborn, Anna Mühlig, Orlando Guntinas-Lichius, Micheal Schmitt, Jürgen Popp

Proceedings Volume PC12839, PC1283906 (2024) https://doi.org/10.1117/12.3009975

KEYWORDS: Tissues, Cancer, Imaging systems, Diagnostics, Laser ablation, Second harmonic generation, Neck, Head, Femtosecond phenomena, Endoscopy

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Proceedings Article | 13 March 2024 Presentation

Compact fiber-based sources for broad-range CARS and SRS imaging

Sven Breitkopf, Florian Just, Christian Gaida, Oliver Herrfurth, Tobias Meyer-Zedler, Jürgen Popp, Tino Eidam, Jens Limpert

Proceedings Volume PC12827, PC1282706 (2024) https://doi.org/10.1117/12.3002470

KEYWORDS: CARS tomography, Microscopy, Laser sources, Thermal effects, Resistance, Raman spectroscopy, Photonic crystal fibers, Laser frequency, Laser development, Four wave mixing

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Proceedings Article | 13 March 2024 Presentation + Paper

Miniaturized CARS endomicroscopic probe with a large field of view using a MEMS mirror scanner: concept and design considerations

Tobias Habisreuther, Chenting Lai, Aida Amantayeva, Karl Reichwald, Sandra Gerlach-Anhut, Tobias Meyer-Zedler, Adrian Lorenz, Bernhard Messerschmidt, Jörg Bierlich

Proceedings Volume 12820, 1282003 (2024) https://doi.org/10.1117/12.3003833

KEYWORDS: Mirrors, Microelectromechanical systems, Miniaturization, Blazed gratings, Tissues, Design, Diffraction gratings, Second harmonic generation, Diffraction, Cladding, Endomicroscopy, MEMS based endomicroscopy, Nonlinear endomicroscopy, Miniature imaging systems

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Proceedings Article | 12 March 2024 Presentation + Paper

Ultrabroadband two-beam CARS as a tool in diagnostics and therapy

Stefan Nolte, Timea Koch, Axel Stöcker, Jeannine Mißbach-Güntner, Thomas Gabler, Tobias Meyer-Zedler, Christoph Rußmann, Tom Lippoldt, Roland Ackermann

Proceedings Volume 12875, 1287502 (2024) https://doi.org/10.1117/12.3009765

KEYWORDS: Raman spectroscopy, Pulse signals, Diagnostics, Tissues, Ablation, Ultrafast phenomena, Signal intensity, Raman scattering, Femtosecond pulse shaping, Bioalcohols

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SPIE Journal Paper | 28 June 2023 Open Access

Design and test of a rigid endomicroscopic system for multimodal imaging and femtosecond laser ablation

Chenting Lai, Matteo Calvarese, Karl Reichwald, Hyeonsoo Bae, Mohammadsadegh Vafaeinezhad, Tobias Meyer-Zedler, Franziska Hoffmann, Anna Mühlig, Tino Eidam, Fabian Stutzki, Bernhard Messerschmidt, Herbert Gross, Michael Schmitt, Orlando Guntinas-Lichius, Jürgen Popp

JBO, Vol. 28, Issue 06, 066004, (June 2023) https://doi.org/10.1117/12.10.1117/1.JBO.28.6.066004

KEYWORDS: Tissues, Laser ablation, Imaging systems, Multimodal imaging, Femtosecond phenomena, Biological samples, Pulse signals, Design and modelling, Image resolution, Fluorescence

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Proceedings Article | 25 April 2023 Presentation + Paper

Multiphoton imaging in conjunction with ICG imaging by a rigid endomicroscope combined with laser ablation in the head and neck region

Sven Flämig, Chenting Lai, Bernhard Messerschmidt, Karl Reichwald, Tino Eidam, Fabian Stutzki, Matteo Calvarese, Hyeonsoo Bae, Tobias Meyer-Zedler, Michael Schmitt, Herbert Gross, Franziska Hoffmann, Orlando Guntinas-Lichius, Juergen Popp

Proceedings Volume 12384, 123840G (2023) https://doi.org/10.1117/12.2650213

KEYWORDS: Tissues, Laser ablation, Head, Neck, Second harmonic generation, Pulse signals, Indocyanine green, Imaging systems, Biological samples, Tumors

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Proceedings Article | 16 March 2023 Presentation

Ultra-compact widely tunable dual-wavelength fiber-based sources for CARS and SRS imaging (Conference Presentation)

Sven Breitkopf, Armin Hoffmann, Florian Just, Christian Gaida, Oliver Herrfurth, Tobias Meyer-Zedler, Jürgen Popp, Tino Eidam, Jens Limpert

Proceedings Volume PC12391, PC123910S (2023) https://doi.org/10.1117/12.2649987

KEYWORDS: CARS tomography, Microscopy, Laser sources, Thermal effects, Raman spectroscopy, Fiber lasers

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Proceedings Article | 14 March 2023 Presentation + Paper

Rigid endomicroscopic system for multiphoton imaging and tissue ablation in the head and neck region

Chenting Lai, Bernhard Messerschmidt, Karl Reichwald, Sven Flämig, Tino Eidam, Fabian Stutzki, Matteo Calvarese, Hyeonsoo Bae, Tobias Meyer-Zedler, Michael Schmitt, Herbert Gross, Franziska Hoffmann, Orlando Guntinas-Lichius, Juergen Popp

Proceedings Volume 12356, 1235609 (2023) https://doi.org/10.1117/12.2650081

KEYWORDS: Imaging systems, Tissues, Head, Neck, Pulse signals, Laser ablation, Ablation, Tumors, Second harmonic generation, Femtosecond phenomena

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Proceedings Article | 27 May 2022 Presentation + Paper

Multimodal handheld endomicroscopic system designed for in vivo laser ablation and nonlinear imaging with a large field of view

Chenting Lai, Bernhard Messerschmidt, Sven Flämig, Karl Reichwald, Hyeonsoo Bae, Tobias Meyer, Michael Schmitt, Orlando Guntinas-Lichius, Jürgen Popp, Matteo Calvarese, Franziska Hoffmann

Proceedings Volume 12144, 1214408 (2022) https://doi.org/10.1117/12.2621692

KEYWORDS: Laser ablation, Imaging systems, Laser tissue interaction, Confocal microscopy, Tissues, Second-harmonic generation, Scanners, Mirrors, Monochromatic aberrations

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Proceedings Article | 5 March 2021 Presentation + Paper

CARS endomicroscopic imaging probe enabled by a double-core double-clad fiber and related focus-combining micro-optical concept

Bernhard Messerschmidt, Ekaterina Pshenay-Severin, Gregor Matz, Karl Reichwald, Jörg Bierlich, Jens Kobelke, Hyeonsoo Bae, Tobias Meyer-Zedler, Jürgen Popp, Michael Schmitt

Proceedings Volume 11636, 116360A (2021) https://doi.org/10.1117/12.2578538

KEYWORDS: CARS tomography, Endoscopy, Tissues, Silica, Signal processing, Image processing, Fiber lasers, Coherence imaging, Surgery, Signal generators

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SPIE Journal Paper | 7 January 2021 Open Access

FLIM data analysis based on Laguerre polynomial decomposition and machine-learning

Shuxia Guo, Anja Silge, Hyeonsoo Bae, Tatiana Tolstik, Tobias Meyer, Georg Matziolis, Michael Schmitt, Jürgen Popp, Thomas Bocklitz

JBO, Vol. 26, Issue 02, 022909, (January 2021) https://doi.org/10.1117/12.10.1117/1.JBO.26.2.022909

KEYWORDS: Fluorescence lifetime imaging, Data modeling, Data analysis, Liver, Luminescence, Chemometrics, Computer simulations, Visualization, Laser phosphor displays, Picosecond phenomena

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Proceedings Article | 1 April 2020 Presentation + Paper

Coherent anti-Stokes Raman scattering microscopy through a multimode fiber endoscope

Johanna Trägårdh, Tomáš Pikálek, Mojmír Šerý, Denis Akimov, Tobias Meyer, Jürgen Popp, Tomáš Cižmár

Proceedings Volume 11359, 1135907 (2020) https://doi.org/10.1117/12.2555080

KEYWORDS: Multimode fibers, Spatial light modulators, Endoscopes, Polarization, Microscopy, CARS tomography, Signal detection, Second-harmonic generation, Speckle pattern, Calibration

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Proceedings Article | 22 February 2019 Paper

Virtual HE histology by fiber-based picosecond two-photon microscopy

Wolfgang Draxinger, Jan Philip Kolb, Daniel Weng, Hubertus Hakert, Sebastian Nino Karpf, Robert Huber, Jürgen Popp, Tobias Meyer, Jens Limpert, Thomas Gottschall, Matthias Eibl, Ralf Brinkmann, Reginald Birngruber

Proceedings Volume 10882, 108822F (2019) https://doi.org/10.1117/12.2507866

KEYWORDS: Luminescence, Femtosecond phenomena, Picosecond phenomena, Fiber lasers, Optical filters, Tissues, Laser systems engineering, Objectives, Microscopes

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Proceedings Article | 29 April 2017 Paper

Non-linear multimodal imaging for disease diagnostics and treatment monitoring

Thomas Bocklitz, Michael Schmitt, Aleksandar Lukić, Sandro Heuke, Olga Chernavskaia, Tobias Meyer, Jürgen Popp

Proceedings Volume 10340, 103400F (2017) https://doi.org/10.1117/12.2275361

KEYWORDS: Diagnostics, Multimodal imaging, Image analysis, Cancer, Image processing, Image enhancement, Second-harmonic generation, Feature extraction, Tissues, Statistical analysis, Optical parametric oscillators, Visualization

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Proceedings Article | 22 February 2017 Paper

All-fiber optical parametric oscillator for bio-medical imaging applications

Thomas Gottschall, Tobias Meyer, Cesar Jauregui, Michael Schmitt, Jürgen Popp, Jens Limpert, Andreas Tünnermann, Tino Eidam, Florian Just

Proceedings Volume 10083, 100831E (2017) https://doi.org/10.1117/12.2250484

KEYWORDS: Optical parametric oscillators, Tunable lasers, Fiber lasers, Signal to noise ratio, Laser systems engineering, Four wave mixing, Laser optics, Optical fibers, Microscopy, Raman scattering, Imaging systems, Oscillators, Interference (communication), Photonic crystal fibers

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Proceedings Article | 3 May 2016 Presentation

Multimodal nonlinear microscopy of biopsy specimen: towards intraoperative diagnostics (Conference Presentation)

Michael Schmitt, Sandro Heuke, Tobias Meyer, Olga Chernavskaia, Thomas Bocklitz, Juergen Popp

Proceedings Volume 9704, 97040H (2016) https://doi.org/10.1117/12.2216043

KEYWORDS: Tissues, In vivo imaging, Microscopy, Diagnostics, Biopsy, Chemical analysis, Tissue optics, Spectroscopy, Molecules, Real time imaging

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Proceedings Article | 14 March 2016 Paper

Four-wave mixing based light sources for real-world biomedical applications of coherent Raman microscopy

Jens Limpert, Andreas Tünnermann, Cesar Jauregui, Thomas Gottschall, Tobias Meyer, Michael Schmitt, Jürgen Popp

Proceedings Volume 9712, 971202 (2016) https://doi.org/10.1117/12.2212213

KEYWORDS: Fiber lasers, Four wave mixing, CARS tomography, Light sources, Raman scattering, Optical parametric oscillators, Chromium, Tunable lasers, Neodymium, Oscillators

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Proceedings Article | 5 March 2015 Paper

Non-linear imaging and characterization of atherosclerotic arterial tissue using combined SHG and FLIM microscopy

Riccardo Cicchi, Christian Matthäus, Tobias Meyer, Annika Lattermann, Benjamin Dietzek, Bernhard Brehm, Jürgen Popp, Francesco Pavone

Proceedings Volume 9329, 932919 (2015) https://doi.org/10.1117/12.2078892

KEYWORDS: Collagen, Tissues, Second-harmonic generation, Microscopy, Fluorescence lifetime imaging, Diagnostics, Image analysis, Luminescence, Tissue optics, Nonlinear optics

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Proceedings Article | 20 March 2014 Paper

Interpreting CARS images of tissue within the C-H-stretching region

Rolf Kalff, Rupert Reichart, Bernd F. M. Romeike, Benjamin Dietzek, Tobias Meyer, Christoph Krafft, Anna Medyukhina, Michael Schmitt, Norbert Bergner, Jürgen Popp

Proceedings Volume 8928, 892806 (2014) https://doi.org/10.1117/12.2036547

KEYWORDS: Tissues, Microscopy, Raman spectroscopy, Molecules, Proteins, CARS tomography, Tissue optics, Brain, Image segmentation, Spectral resolution

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Proceedings Article | 28 February 2014 Paper

Non-linear imaging and characterization of atherosclerotic arterial tissue using combined two photon fluorescence, second-harmonic generation and CARS microscopy

Riccardo Cicchi, Christian Matthäus, Tobias Meyer, Annika Lattermann, Benjamin Dietzek, Bernhard Brehm, Jürgen Popp, Francesco Pavone

Proceedings Volume 8948, 894807 (2014) https://doi.org/10.1117/12.2037018

KEYWORDS: Second-harmonic generation, Collagen, Tissues, Microscopy, Signal detection, Image analysis, Tissue optics, Diagnostics, Nonlinear optics, Luminescence

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Proceedings Article | 17 June 2013 Paper

Characterization of atherosclerotic arterial tissue using multimodal non-linear optical microscopy

Riccardo Cicchi, Christian Matthäus, Tobias Meyer, Annika Lattermann, Benjamin Dietzek, Bernhard Brehm, Jürgen Popp, Francesco Pavone

Proceedings Volume 8797, 87970D (2013) https://doi.org/10.1117/12.2030879

KEYWORDS: Second-harmonic generation, Collagen, Tissues, Microscopy, Signal detection, Image analysis, Tissue optics, Nonlinear optics, Diagnostics, In vivo imaging

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Proceedings Article | 8 May 2012 Paper

Non-invasive label-free investigation and typing of head and neck cancers by multimodal nonlinear microscopy

Jürgen Popp, Orlando Guntinas-Lichius, Benjamin Dietzek, Nadine Vogler, Tobias Meyer, Johanna Inhestern, Denis Akimov

Proceedings Volume 8427, 84270Z (2012) https://doi.org/10.1117/12.921631

KEYWORDS: Tissues, Tumors, Head, Neck, Second-harmonic generation, Cancer, Visualization, Tissue optics, Collagen, Connective tissue

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Proceedings Article | 1 February 2012 Paper

Monitoring the morphochemistry of laryngeal carcinoma by multimodal imaging

Benjamin Dietzek, Jürgen Popp, Günther Ernst, Christoph Krafft, Orlando Guntinas-Lichius, Tobias Meyer, Ferdinand von Eggeling

Proceedings Volume 8220, 82200R (2012) https://doi.org/10.1117/12.906180

KEYWORDS: Tissues, Second-harmonic generation, Tumors, Multimodal imaging, Visualization, Cancer, Luminescence, Image resolution, Connective tissue, Microscopy

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Proceedings Article | 30 January 2012 Paper

Alignment and maintenance free all-fiber laser source for CARS microscopy based on frequency conversion by four-wave-mixing

Martin Baumgartl, Jens Limpert, Tobias Meyer, Jürgen Popp, Andreas Tünnermann, Benjamin Dietzek, Mario Chemnitz, Cesar Jauregui

Proceedings Volume 8247, 82470F (2012) https://doi.org/10.1117/12.908170

KEYWORDS: Frequency conversion, Microscopy, Picosecond phenomena, Fiber lasers, Laser sources, Oscillators, Pulsed laser operation, Photonic crystal fibers, Laser systems engineering, Laser applications

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Proceedings Article | 18 February 2011 Paper

Nonlinear optical imaging: toward chemical imaging during neurosurgery

Christoph Krafft, Rupert Reichart, Rolf Kalff, Tobias Meyer, Jürgen Popp, Bernd F. Romeike, Benjamin Dietzek

Proceedings Volume 7883, 78833W (2011) https://doi.org/10.1117/12.873375

KEYWORDS: Second-harmonic generation, Tissues, Brain, Tumors, Microscopy, Signal detection, Multimodal imaging, CARS tomography, Microscopes, Neuroimaging

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Proceedings Article | 11 February 2011 Paper

Nonlinear microscopy and infrared and Raman microspectroscopy for brain tumor analysis

Benjamin Dietzek, Jürgen Popp, Tobias Meyer, Rolf Kalff, Norbert Bergner, Rupert Reichart, Christoph Krafft, Bernd F. Romeike

Proceedings Volume 7903, 790319 (2011) https://doi.org/10.1117/12.872711

KEYWORDS: Tumors, Raman spectroscopy, Brain, Tissues, FT-IR spectroscopy, Microscopy, Neuroimaging, Microscopes, Solids, Spectroscopy

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SPIE Journal Paper | 1 February 2011 Open Access

Nonlinear microscopy, infrared, and Raman microspectroscopy for brain tumor analysis

Tobias Meyer, Norbert Bergner, Christoph Krafft, Denis Akimov, Benjamin Dietzek, Jürgen Popp, Christiane Bielecki, Bernd Romeike, Rupert Reichart, Rolf Kalff

JBO, Vol. 16, Issue 02, 021113, (February 2011) https://doi.org/10.1117/12.10.1117/1.3533268

KEYWORDS: Tumors, Raman spectroscopy, Brain, Tissues, Second-harmonic generation, Microscopy, Neuroimaging, FT-IR spectroscopy, Infrared imaging, Imaging spectroscopy

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