Prof. Tuan Vo-Dinh Profile

Prof. Tuan Vo-Dinh

Distinguished Professor of Biomedical Engineering at Duke Univ

SPIE Involvement:

Conference Program Committee | Conference Chair | Track Chair | Editor | Author

Publications (134)

Proceedings Article | 13 March 2024 Presentation

Bimetallic silver-gold nanostars: synthesis, surface modification, and application in SERS sensing

Supriya Atta, Tuan Vo-Dinh

Proceedings Volume PC12860, PC1286003 (2024) https://doi.org/10.1117/12.3003586

KEYWORDS: Localized surface plasmon resonances, Optical properties, Gold nanoparticles, Silver, Scattering, Resonance enhancement, Reproducibility, Plasmons, Pesticides, Gold

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Proceedings Article | 13 March 2024 Presentation

Colloidal gold nanostars for biomedical sensing application

Supriya Atta, Tuan Vo-Dinh

Proceedings Volume PC12859, PC1285903 (2024) https://doi.org/10.1117/12.3003581

KEYWORDS: Gold, Biomedical applications, Surface enhanced Raman spectroscopy, Biosensing, Plasmonics, Metals, Localized surface plasmon resonances, Gold nanoparticles, Sensors, Reproducibility

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Proceedings Article | 13 March 2024 Presentation

Lateral-flow immunoassay using high aspect ratio plasmonic gold nanostars

Supriya Atta, Tuan Vo-Dinh

Proceedings Volume PC12860, PC1286006 (2024) https://doi.org/10.1117/12.3003588

KEYWORDS: Gold, Plasmonics, Gold nanoparticles, Systems modeling, Sensors, Visualization, Silver, Satellite navigation systems, Diseases and disorders, Design and modelling

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Proceedings Article | 31 March 2023 Presentation

Multiplatform and synergetic photothermal heating using plasmonic gold nanostars

Ren Odion, Yang Liu, Stephen Norton, Tuan Vo-Dinh

Proceedings Volume PC12368, PC123680Q (2023) https://doi.org/10.1117/12.2650598

KEYWORDS: Gold, Plasmonics, Absorption, Tissues, Surface enhanced Raman spectroscopy, Oncology, Cancer, Tissue optics, Thermography, Thermal effects

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Proceedings Article | 17 March 2023 Presentation

Plasmonic nanostars: Synthesis, characterization, surface modification, and applications in sensing, imaging, and photothermal therapy (Conference Presentation)

Aidan Canning, Supriya Atta, Ren Odion, Tuan Vo-Dinh

Proceedings Volume PC12395, PC1239506 (2023) https://doi.org/10.1117/12.2650930

KEYWORDS: Plasmonics, Nanoparticles, Particles, In vivo imaging, Optical properties, Imaging spectroscopy, Tumors, Gold, X-rays, X-ray microscopy

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Proceedings Article | 16 March 2023 Presentation

Stand-off system for remote Raman detection of miRNA biomarkers using shifted excitation Raman difference spectroscopy (Conference Presentation)

Ren Odion, Vanessa Cupil-Garcia, Hsin-Neng Wang, Aidan Canning, Jianhong Hu, Martin Maiwald, Bernd Sumpf, Tai-Ping Sun, Tuan Vo-Dinh

Proceedings Volume PC12396, PC1239601 (2023) https://doi.org/10.1117/12.2650554

KEYWORDS: Raman spectroscopy, Spectroscopy, Target detection, Surface enhanced Raman spectroscopy, Diagnostics, Biosensing, Biofuels, Signal detection, Polymers, Plasmonics

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Proceedings Article | 16 March 2023 Presentation

Multiplexed detection of cancer biomarkers using inverse molecular sentinel integrated on plasmonic bimetallic nanostar substrate (Conference Presentation)

Aidan Canning, Xinrong Chen, Hsin-Neng Wang, Tuan Vo-Dinh

Proceedings Volume PC12396, PC1239603 (2023) https://doi.org/10.1117/12.2650723

KEYWORDS: Multiplexing, Cancer, Plasmonics, Target detection, Error control coding, Colorectal cancer, Raman scattering, Profiling, Point-of-care devices, Plasma

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Proceedings Article | 16 March 2023 Presentation

The ORCHID system for 3D hyperspectral imaging of plasmonic nanosystems (Conference Presentation)

Ren Odion, Tuan Vo-Dinh

Proceedings Volume PC12396, PC1239606 (2023) https://doi.org/10.1117/12.2668230

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Proceedings Article | 16 March 2023 Presentation

Colorimetric detection of microRNA biomarkers using plasmonic nanoplatforms on a smartphone (Conference Presentation)

Tushar Krishnan, Ren Odion, Hsin-Neng Wang, Tuan Vo-Dinh

Proceedings Volume PC12396, PC123960F (2023) https://doi.org/10.1117/12.2650585

KEYWORDS: Plasmonics, Cancer, Target detection, Sensing systems, Point-of-care devices, Diagnostics, 3D acquisition

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Proceedings Article | 3 March 2022 Poster + Paper

In vivo SERS monitoring in plants using plasmonic nanoprobes

Vanessa Cupil-Garcia, Joy Li, Ren Odion, Pietro Strobbia, Bridget Crawford, Hsin-neng Wang, Jianhong Hu, Rodolfo Zentella, Kenneth Kemner, Tai-ping Sun, Tuan Vo-Dinh

Proceedings Volume 11978, 119780B (2022) https://doi.org/10.1117/12.2617364

KEYWORDS: Raman spectroscopy, Nanoprobes, Surface enhanced Raman spectroscopy, In vivo imaging, Gold, Plasmonics, Nanoparticles, Biofuels, Transmission electron microscopy

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Proceedings Article | 3 March 2022 Presentation + Paper

Analysis of SERS spectra of plasmonic nanoprobes for multiplexed biomarker detection using machine learning

Joy Li, Tuan Vo-Dinh

Proceedings Volume 11978, 1197805 (2022) https://doi.org/10.1117/12.2617363

KEYWORDS: Surface enhanced Raman spectroscopy, Multiplexing, Raman spectroscopy, Machine learning, Plasmonics, Nanoparticles, Diagnostics, Statistical analysis

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Proceedings Article | 12 March 2021 Presentation + Paper

Translation of SERS sensing to real-world settings through the combination with shifted-excitation Raman difference spectroscopy (SERDS)

Pietro Strobbia, Vanessa Cupil-Garcia, Ren Odion, Bridget Crawford, Hsin-Neng Wang, Yang Liu, Martin Maiwald, Bernd Sumpf, Tuan Vo-Dinh

Proceedings Volume 11661, 1166103 (2021) https://doi.org/10.1117/12.2583914

KEYWORDS: Raman spectroscopy, Surface enhanced Raman spectroscopy, Spectroscopy, Tumors, Sensors, Laser development, In vivo imaging, Raman scattering, Nanoprobes

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Proceedings Article | 21 February 2020 Presentation + Paper

Fiberoptics SERS sensors using plasmonic nanostar probes for detection of molecular biotargets

Vanessa Cupil-Garcia, Pietro Strobbia, Yang Ran, Bridget Crawford, Hsin-neng Wang, Rodolfo Zentella, Tai-Ping Sun, Tuan Vo-Dinh

Proceedings Volume 11257, 112570O (2020) https://doi.org/10.1117/12.2552993

KEYWORDS: Surface enhanced Raman spectroscopy, Sensors, Rhodamine B, Fiber optics sensors, Gold, Raman spectroscopy, Silver, Plasmonics, Signal detection, Fiber optics

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Proceedings Article | 21 February 2020 Paper

Nanostar probes: a golden platform for Synergistic Immuno Photothermal Nanotherapy (SYMPHONY) for the treatment of metastatic cancer

Vanessa Cupil-Garcia, Yang Liu, Bridget Crawford, Pakawat Chongsathidkiet, Gregory Palmer, Paolo Maccarini, Peter Fecci, Brant Inman, Tuan Vo-Dinh

Proceedings Volume 11257, 1125714 (2020) https://doi.org/10.1117/12.2552995

KEYWORDS: Tumors, Cancer, Oncology, Bladder cancer, Gold, Nanoparticles, Nanotherapeutics, Near infrared, Tumor growth modeling, Computed tomography

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Proceedings Article | 21 February 2020 Paper

Applications of plasmonic nanoparticles for in vivo biosensing of plants

Vanessa Cupil-Garcia, Pietro Strobbia, Bridget Crawford, Hsin-neng Wang, Rodolfo Zentella, Tai-Ping Sun, Tuan Vo-Dinh

Proceedings Volume 11257, 1125715 (2020) https://doi.org/10.1117/12.2553020

KEYWORDS: Raman spectroscopy, Nanoprobes, In vivo imaging, Gold, Nanoparticles, Temporal resolution, Plasmonics, Target detection, Biosensing, Spatial resolution

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Proceedings Article | 9 September 2019 Presentation + Paper

Direct detection of cancer biomarkers using plasmonics-based Inverse Molecular Sentinel (iMS) nanobiosensors

Bridget Crawford, Hsin-Neng Wang, Michelle Bowie, Victoria Seewaldt, Tuan Vo-Dinh

Proceedings Volume 11087, 1108702 (2019) https://doi.org/10.1117/12.2529832

KEYWORDS: Nanoprobes, Cancer, Raman spectroscopy, Surface enhanced Raman spectroscopy, Raman scattering, Diagnostics, Nanoparticles, Plasmonics

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Proceedings Article | 9 September 2019 Presentation + Paper

In vivo detection of microRNA within plants using plasmonic nanosensors

Bridget Crawford, Pietro Strobbia, Hsin-Neng Wang, Rodolfo Zentella, Maxim Boyanov, Zhen-Ming Pei, Tai-Ping Sun, Kenneth Kemner, Tuan Vo-Dinh

Proceedings Volume 11082, 1108215 (2019) https://doi.org/10.1117/12.2529818

KEYWORDS: Nanoprobes, Raman spectroscopy, Nanoparticles, In vivo imaging, Plasmonics, Biosensing, Plasmonic sensors

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Proceedings Article | 9 September 2019 Paper

Inverse molecular sentinel-integrated fiber sensor for direct detection of miRNA targets

Pietro Strobbia, Yang Ran, Bridget Crawford, Vanessa Cupil-Garcia, Rodolfo Zentella, Hsin-Neng Wang, Tai-ping Sun, Tuan Vo-Dinh

Proceedings Volume 11082, 110822L (2019) https://doi.org/10.1117/12.2529844

KEYWORDS: Fiber optics sensors, Target detection, Sensors, Raman spectroscopy, Nanosensors, Optical fibers

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Proceedings Article | 10 May 2019 Paper

In vivo nucleic acid detection and imaging within whole plants using plasmonic nanosensors

Bridget Crawford, Pietro Strobbia, Hsin-Neng Wang, Rodolfo Zentella, Maxim Boyanov, Ren Odion, Zhen-Ming Pei, Tai-Ping Sun, Kenneth Kemner, Tuan Vo-Dinh

Proceedings Volume 11007, 1100708 (2019) https://doi.org/10.1117/12.2524840

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Proceedings Article | 10 May 2019 Presentation + Paper

Surface-enhanced spatially offset Raman spectroscopy (SESORS) for subsurface detection of nanostar probes

Ren Odion, Pietro Strobbia, Bridget Crawford, Tuan Vo-Dinh

Proceedings Volume 11007, 110070I (2019) https://doi.org/10.1117/12.2524847

KEYWORDS: Raman spectroscopy, Skull, Surface enhanced Raman spectroscopy, Nanoparticles, Bone, Tissue optics, Raman scattering, Signal detection, Scattering, Molecular spectroscopy

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Proceedings Article | 7 March 2019 Paper

Implantable "smart tattoo" SERS nanosensors for in vivo detection of nucleic acid biotargets in a large animal model

Hsin-Neng Wang, Janna Register, Andrew Fales, Naveen Gandra, Pietro Strobbia, Eugenia Cho, Alina Boico, Gregory Palmer, Bruce Klitzman, Tuan Vo-Dinh

Proceedings Volume 10894, 108941J (2019) https://doi.org/10.1117/12.2514634

KEYWORDS: Nanosensors, Animal model studies, Sensors, Raman spectroscopy, Plasmonics

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Proceedings Article | 7 March 2019 Presentation + Paper

Application of plasmonic nanoprobes for SERS sensing and imaging of biotargets in plant systems

Pietro Strobbia, Bridget Crawford, Hsin-Neng Wang, Rodolfo Zentella, Maxim Boyanov, Zhen-Ming Pei, Tai-Ping Sun, Kenneth Kemner, Tuan Vo-Dinh

Proceedings Volume 10894, 108940C (2019) https://doi.org/10.1117/12.2512010

KEYWORDS: Nanoprobes, Raman spectroscopy, Imaging systems, In vivo imaging, Functional imaging, Plasmonics, Biofuels

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Proceedings Article | 4 March 2019 Presentation

SYMPHONY: a new concept of plasmonics-amplified immunotherapy for cancer treatment

Tuan Vo-Dinh, Brant Inman

Proceedings Volume 10894, 1089405 (2019) https://doi.org/10.1117/12.2512334

KEYWORDS: Cancer, Tumors, Oncology, Nanoparticles, Plasmonics, Nanotherapeutics, Medicine, Electromagnetism, Nanomedicine, Optical properties

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Cancer is the most common cause of death in people aged less than 85 years and it is estimated that in 2012 there were more than 14.1 million new cancer cases worldwide and 8.2 million deaths that resulted [1]. Nanomedicine has contributed to important advances in health care over the past few decades. In particular, the use of nanoparticles in medicine has attracted increased attention for their unique efficacy and specificity in therapy. A special type of metallic nanoparticles, called “plasmonic” nanoparticles, has received great interest because they exhibit enhanced optical and electromagnetic properties. Plasmonic nanoparticles have unique properties that allow them to amplify the optical properties of the excitation light and thus increase the effectiveness of light-based photothermal tumor ablation. Among nanoparticles used for light-induced photothermal therapy, gold nanostars (GNS) are of particular interest because their structure has multiple sharp branches that produce the numerous curvatures responsible for the ‘lightning rod’ effect that strongly enhances the local electromagnetic field when subject to light stimulation. As with other nanoparticles, GNS sizes can be controlled so that they passively accumulate in tumors due to the enhanced permeability and retention (EPR) effect of tumor vasculature. The combination of the EPR effect and the capacity for efficient photon to heat conversion, make GNS an ideal photothermal transducer for selective cancer therapy at the nanoscale level, as we have demonstrated both in vitro and in vivo. The unique properties of GNS which contribute to plasmonics-amplified immune nanotherapy for cancer, include: (1) plasmonic nano-enhancers of light, (2) nano-targeting of tumor cells, (3) nano-sources for heating tumor cells from the inside (4) nano-activators of the immune system, and (5) synergistic amplification of immunomodulation. These elements will be discussed in detail. We demonstrated that the use of plasmonic nanoparticles in combination with immunotherapy—a treatment we referred to as Synergistic Immuno Photothermal Nanotherapy (SYMPHONY)—can dramatically enhance the efficacy of immunotherapy [2]. Remarkably, we have found that SYMPHONY not only eradicates primary “treated” tumors but also has resulted in the immune-mediated destruciton of distant “untreated” metastatic tumors. This abscopal effect occurred uniquely when nanoparticle tumor heating was used in combination with immunotherapy. This strategy could lead to an entirely new treatment paradigm that challenges traditional surgical resection approaches for many cancers and metastases. Of great importance is the possibility that such an approach can induce long-term immunological memory that can provide protection against tumor recurrence long after treatment of the initial tumors similar to an “anti-cancer vaccine”. [1] World Health Organization, Latest world cancer statistics: Global cancer burden rises to 14.1 million new cases in 2012: Marked increase in breast cancers must be addressed [2] Liu Y, Maccarini P, Palmer GM, Etienne W, Zhao Y, Lee C, Ma X, Inman BA, Vo-Dinh T. Synergistic Immuno Photothermal Nanotherapy (SYMPHONY) for the Treatment of Unresec-table and Metastatic Cancers. Scientific Reports. 7, 8606 (2017).

Proceedings Article | 26 February 2019 Presentation + Paper

A nanophotonic-based assay for point-of-care medical diagnostics of malaria in low and middle income countries

Hoan Ngo, Pietro Strobbia, Priya Vohra, Elizabeth Freedman, Agampodi Swarnapali De Silva Indrasekara, Walter Lee, Steve Taylor, Tuan Vo-Dinh

Proceedings Volume 10869, 108690V (2019) https://doi.org/10.1117/12.2512012

KEYWORDS: Target detection, Point-of-care devices, Signal detection, Diagnostics, Blood, Medical diagnostics, Surface enhanced Raman spectroscopy

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Proceedings Article | 26 February 2019 Presentation + Paper

Direct detection of nanostar probes through a monkey skull using inverse surface-enhanced spatially offset Raman spectroscopy (SESORS)

Ren Odion, Pietro Strobbia, Bridget Crawford, Tuan Vo-Dinh

Proceedings Volume 10868, 108680B (2019) https://doi.org/10.1117/12.2512011

KEYWORDS: Skull, Surface enhanced Raman spectroscopy, Nanoparticles, Raman spectroscopy, Bone, Raman scattering, Tissue optics

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Proceedings Article | 12 February 2018 Paper

Synergistic immuno photothermal nanotherapy (SYMPHONY) to treat unresectable and metastatic cancers and produce and cancer vaccine effect

Tuan Vo-Dinh, Brant Inman, Paolo Maccarini, Gregory Palmer, Yang Liu

Proceedings Volume 10484, 1048408 (2018) https://doi.org/10.1117/12.2300089

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Proceedings Article | 12 February 2018 Paper

Surface-enhanced patially offset Raman spectroscopy (SESORS) for biomedical applications

Ren Odion, Pietro Strobbia, Tuan Vo-Dinh

Proceedings Volume 10484, 1048404 (2018) https://doi.org/10.1117/12.2300088

KEYWORDS: Raman spectroscopy, Surface enhanced Raman spectroscopy, Nanoparticles, Tissue optics, Signal detection, Gold, Raman scattering, Photons, Scattering, Particles

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Proceedings Article | 8 February 2018 Paper

Creation of an optically tunable, solid tissue phantom for use in cancer detection

Matthew Tucker, Catherine Wallace, Sreekar Mantena, Neil Cornwell, Weston Ross, Ren Odion, Tuan Vo-Dinh, Patrick Codd

Proceedings Volume 10480, 104800H (2018) https://doi.org/10.1117/12.2290499

KEYWORDS: Tissues, Solids, Tissue optics, Cancer, Luminescence, Data modeling, Fluorescence spectroscopy, Error analysis, Principal component analysis, Surgery

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Proceedings Article | 3 May 2017 Presentation + Paper

Plasmonic nanochip for SERS chemical and biomedical sensing

Hoan Ngo, Pietro Strobbia, Hsin-Neng Wang, Bridget Crawford, Andrew Fales, Tuan Vo-Dinh

Proceedings Volume 10215, 102150G (2017) https://doi.org/10.1117/12.2267759

KEYWORDS: Surface enhanced Raman spectroscopy, Plasmonics, Biosensing, Biosensors, Raman scattering, Target detection, Raman spectroscopy, Medical diagnostics, Signal detection, Genetics

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Proceedings Article | 3 May 2017 Presentation + Paper

Nanosensors for nucleic acid targets detection using SERS

Pietro Strobbia, Bridget Crawford, Hsin-Neng Wang, Tuan Vo-Dinh

Proceedings Volume 10215, 1021508 (2017) https://doi.org/10.1117/12.2267757

KEYWORDS: Surface enhanced Raman spectroscopy, Nanosensors, Target detection, Biosensors, Raman spectroscopy, Optical fibers, Nanoprobes, Gold, Microscopes, Biological research

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Proceedings Article | 17 February 2017 Paper

SERS-based inverse molecular sentinel (iMS) nanoprobes for multiplexed detection of microRNA cancer biomarkers in biological samples

Bridget Crawford, Hsin-Neng Wang, Andrew Fales, Michelle Bowie, Victoria Seewaldt, Tuan Vo-Dinh

Proceedings Volume 10080, 1008008 (2017) https://doi.org/10.1117/12.2258272

KEYWORDS: Target detection, Cancer, Nanoprobes, Multiplexing, Surface enhanced Raman spectroscopy, Raman scattering, Diagnostics, Plasmonics, Biosensors, Raman spectroscopy, Signal detection, Breast cancer, Signal processing, Gold, Biosensing

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Proceedings Article | 17 February 2017 Presentation + Paper

Plasmonic SERS nanochips and nanoprobes for medical diagnostics and bio-energy applications

Hoan Ngo, Hsin-Neng Wang, Bridget Crawford, Andrew Fales, Tuan Vo-Dinh

Proceedings Volume 10080, 100800A (2017) https://doi.org/10.1117/12.2267857

KEYWORDS: Chemical analysis, Surface enhanced Raman spectroscopy, Plasmonics, Nanoprobes, Medical diagnostics, Biosensors, Raman scattering, Target detection, Raman spectroscopy, Signal detection, Gold, Genetics

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Proceedings Article | 14 February 2017 Presentation + Paper

DNA detection and single nucleotide mutation identification using SERS for molecular diagnostics and global health

Hoan Ngo, Naveen Gandra, Andrew Fales, Steve Taylor, Tuan Vo-Dinh

Proceedings Volume 10054, 100540C (2017) https://doi.org/10.1117/12.2268779

KEYWORDS: Surface enhanced Raman spectroscopy, Diagnostics, Point-of-care devices, Raman scattering, Target detection, Raman spectroscopy, Signal detection, Gold, Nanoparticles, Scanning electron microscopy

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Proceedings Article | 22 April 2016 Paper

Plasmonic fano resonance sensing system using gold nanosphere and J-aggregates

Andrew Fales, Bridget Crawford, Stephen Norton, Brendan DeLacy, Tuan Vo-Dinh

Proceedings Volume 9724, 97240O (2016) https://doi.org/10.1117/12.2222122

KEYWORDS: Nanorods, Photonic integrated circuits, Nanoparticles, Plasmons, Gold, Excitons, Absorption, Plasmonics, Coating, Particles

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Proceedings Article | 13 May 2015 Paper

Plasmonics-active gold nanostars for chemical and biological sensing using SERS detection

Yang Liu, Hsiangkuo Yuan, Andrew Fales, Tuan Vo-Dinh

Proceedings Volume 9486, 948607 (2015) https://doi.org/10.1117/12.2182123

KEYWORDS: Surface enhanced Raman spectroscopy, Gold, Raman spectroscopy, Nanoparticles, Plasmonics, Nanoprobes, Chemical analysis, Raman scattering, Near infrared, Biosensing

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Proceedings Article | 3 March 2014 Paper

Plasmonic gold nanostar for biomedical sensing

Yang Liu, Hsiangkuo Yuan, Andrew Fales, Tuan Vo-Dinh

Proceedings Volume 8957, 895703 (2014) https://doi.org/10.1117/12.2040636

KEYWORDS: Surface enhanced Raman spectroscopy, Raman spectroscopy, Gold, Cancer, Nanoprobes, Plasmonics, Biosensing, Raman scattering, Environmental sensing, Near infrared

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Proceedings Article | 3 March 2014 Paper

Micovascular integration into porous polyHEMA scaffold

Eugenia Cho, Alina Boico, Natalie Wisniewski, Rebecca Gant, Kristen Helton, Nga Brown, Janna Register, Tuan Vo-Dinh, Thies Schroeder, Bruce Klitzman

Proceedings Volume 8958, 89580B (2014) https://doi.org/10.1117/12.2037950

KEYWORDS: Tissues, Interfaces, Sensors, Photomicroscopy, Solids, Surface enhanced Raman spectroscopy, Skin, Silicon, Signal detection, Biological research

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Proceedings Article | 27 February 2014 Paper

Optically enhanced blood-brain-barrier crossing of plasmonic-active nanoparticles in preclinical brain tumor animal models

Hsiangkuo Yuan, Christy Wilson, Shuqin Li, Andrew Fales, Yang Liu, Gerald Grant, Tuan Vo-Dinh

Proceedings Volume 8935, 89350E (2014) https://doi.org/10.1117/12.2040960

KEYWORDS: Tumors, Brain, Blood brain barrier, Nanoparticles, Neuroimaging, Tissues, Gold, Biomedical optics, Animal model studies, Cancer

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Proceedings Article | 17 October 2012 Paper

Optical nanosensors and nanoprobes: from single-cell exploration to medical diagnostics

Tuan Vo-Dinh, Hsin-Neng Wang

Proceedings Volume 8421, 84210S (2012) https://doi.org/10.1117/12.2007658

KEYWORDS: Nanoprobes, Plasmonics, Raman spectroscopy, Nanoparticles, Nanosensors, Fiber optics, Molecules, Medical diagnostics, Biomedical optics, Diagnostics

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Proceedings Article | 22 February 2012 Paper

Plasmonic coupling interference: a new approach for cancer diagnostics using SERS detection

Hsin-Neng Wang, Tuan Vo-Dinh

Proceedings Volume 8214, 821405 (2012) https://doi.org/10.1117/12.917630

KEYWORDS: Plasmonics, Nanoparticles, Silver, Raman spectroscopy, Diagnostics, Biomedical optics, Target detection, Cancer, Nanoprobes, Molecules

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Proceedings Article | 15 April 2011 Open Access

Nanotechnology research and development for military and industrial applications

Paul Ruffin, Christina Brantley, Eugene Edwards, J. Keith Roberts, William Chew, Larry Warren, Paul Ashley, Henry Everitt, Eric Webster, John Foreman, Mohan Sanghadasa, Sihon Crutcher, Mark Temmen, Vijay Varadan, Devlin Hayduke, Pae Wu, Christopher Khoury, Yang Yang, Tong-Ho Kim, Tuan Vo-Dinh, April Brown, John Callahan

Proceedings Volume 7980, 798002 (2011) https://doi.org/10.1117/12.878970

KEYWORDS: Sensors, Raman spectroscopy, Combustion, Missiles, Gallium, Acoustics, Nanotechnology, Microfluidics, Carbon, Nanowires

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SPIE Journal Paper | 1 March 2011 Open Access

Compact point-detection fluorescence spectroscopy system for quantifying intrinsic fluorescence redox ratio in brain cancer diagnostics

Quan Liu, Gerald Grant, Shuqin Li, Christy Wilson, Jianjun Li, Darell Bigner, Yan Zhang, Fangyao Hu, Tuan Vo-Dinh, Kui Chen

JBO, Vol. 16, Issue 03, 037004, (March 2011) https://doi.org/10.1117/12.10.1117/1.3558840

KEYWORDS: Luminescence, Tissues, Tumors, Brain, Fluorescence spectroscopy, Absorption, Diagnostics, Calibration, Brain cancer, Scattering

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Proceedings Article | 1 May 2009 Paper

Fiber optic SERS-based plasmonics nanobiosensing in single living cells

Jonathan Scaffidi, Molly Gregas, Victoria Seewaldt, Tuan Vo-Dinh

Proceedings Volume 7312, 731205 (2009) https://doi.org/10.1117/12.824453

KEYWORDS: Nanoprobes, Fiber optics, Surface enhanced Raman spectroscopy, Raman spectroscopy, Fiber optics tests, Plasmonics, Nanoparticles, Calibration, Microscopes, Raman scattering

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Proceedings Article | 19 February 2009 Paper

Fabrication of novel plasmonics-active substrates

Anuj Dhawan, Michael Gerhold, Yan Du, Veena Misra, Tuan Vo-Dinh

Proceedings Volume 7205, 72050S (2009) https://doi.org/10.1117/12.809887

KEYWORDS: Silicon, Molecules, Nanostructures, Nanolithography, Germanium, Diamond, Raman scattering, Lithography, Metals, Nanowires

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Proceedings Article | 18 February 2009 Paper

Fabrication of metallic nanodot structures using focused ion beam (FIB) and electron beam-induced deposition for plasmonic waveguides

Anuj Dhawan, Michael Gerhold, Phillip Russell, Tuan Vo-Dinh, Donovan Leonard

Proceedings Volume 7224, 722414 (2009) https://doi.org/10.1117/12.809927

KEYWORDS: Nanostructures, Nanolithography, Gold, Nanoparticles, Electron beams, Plasmonic waveguides, Ion beams, Plasmons, Metals, Electron beam-induced deposition

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SPIE Journal Paper | 1 September 2008 Open Access

Spectral bounds on plasmon resonances for Ag and Au prolate and oblate nanospheroids

Stephen Norton, Tuan Vo Dinh

JNP, Vol. 2, Issue 01, 029501, (September 2008) https://doi.org/10.1117/12.10.1117/1.3001731

KEYWORDS: Plasmons, Silver, Gold, Optical spheres, Dielectrics, Particles, Electrons, Data modeling, Nanostructures, Raman scattering

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Proceedings Article | 28 February 2008 Paper

Modeling of amplitude and exit location variations of light propagation under ultrasonic modulation

Quan Liu, Stephen Norton, Tuan Vo-Dinh

Proceedings Volume 6856, 68561Q (2008) https://doi.org/10.1117/12.762326

KEYWORDS: Modulation, Ultrasonics, Refractive index, Sensors, Monte Carlo methods, Phase shift keying, Transmittance, Optical properties, Reflectivity, Ultrasonography

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Proceedings Article | 21 February 2008 Paper

Detection of multidrug-resistant tuberculosis gene using plasmonics nanoprobes

Hsin-Neng Wang, Fei Yan, Yan Zhang, Tuan Vo-Dinh

Proceedings Volume 6869, 686903 (2008) https://doi.org/10.1117/12.761897

KEYWORDS: Nanoprobes, Raman spectroscopy, Surface enhanced Raman spectroscopy, Silver, Nanoparticles, Plasmonics, Metals, Target detection, Diagnostics, Raman scattering

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Proceedings Article | 21 February 2008 Paper

Nano-engineered surface-enhanced Raman scattering (SERS) substrates with patterned structures on the distal end of optical fibers

Anuj Dhawan, Yan Zhang, Fei Yan, Michael Gerhold, Tuan Vo-Dinh

Proceedings Volume 6869, 68690G (2008) https://doi.org/10.1117/12.763879

KEYWORDS: Gold, Nanostructures, Nanoparticles, Optical fibers, Surface plasmons, Electromagnetism, Raman scattering, Annealing, Molecules, Nanorods

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Proceedings Article | 21 February 2008 Paper

Theoretical modeling of plasmon resonances: effect of aspect ratio in spheroidal nanoshells

Stephen Norton, Anuj Dhawan, Michael Gerhold, Tuan Vo-Dinh

Proceedings Volume 6869, 68690Y (2008) https://doi.org/10.1117/12.779203

KEYWORDS: Spherical lenses, Plasmons, Particles, Finite element methods, Optical spheres, Scattering, Plasmonics, Dielectrics, Solids, Nanorods

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Proceedings Article | 11 February 2008 Paper

Geometry-dependent plasmon resonances of metallic nanostructures for enhancement of localized electromagnetic fields around the nanostructures

Michael Gerhold, Anuj Dhawan, Tuan Vo-Dinh

Proceedings Volume 6902, 690208 (2008) https://doi.org/10.1117/12.771440

KEYWORDS: Nanostructures, Electromagnetism, Finite-difference time-domain method, Nanolithography, Optical fibers, Nanoparticles, Ion beams, Gold, Plasmons, Nanorods

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Proceedings Article | 25 September 2007 Paper

Tracking SERS-active nanoprobe intracellular uptake for chemical and biological sensing

Molly Gregas, Fei Yan, Jonathan Scaffidi, Hsin-Neng Wang, Christopher Khoury, Yan Zhang, Tuan Vo-Dinh

Proceedings Volume 6755, 67550H (2007) https://doi.org/10.1117/12.758287

KEYWORDS: Raman spectroscopy, Nanoparticles, Silver, Nanoprobes, Surface enhanced Raman spectroscopy, Particles, Raman scattering, Chemical analysis, Biosensing, Molecules

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Proceedings Article | 25 February 2006 Paper

Hyperspectral fluorescence imaging system for biomedical diagnostics

Matthew Martin, Musundi Wabuyele, Masoud Panjehpour, Mary Phan, Bergein Overholt, Tuan Vo-Dinh

Proceedings Volume 6080, 60800Q (2006) https://doi.org/10.1117/12.664113

KEYWORDS: Tumors, Tissues, Luminescence, Imaging systems, Cancer, Hyperspectral imaging, Diagnostics, Endoscopes, Biopsy, Biomedical optics

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Proceedings Article | 25 February 2006 Paper

Short-pulse laser propagation through tissue medium for tumor detection

Gopalendu Pal, Kunal Mitra, Tuan Vo-Dinh

Proceedings Volume 6080, 608005 (2006) https://doi.org/10.1117/12.664121

KEYWORDS: Tissue optics, Tumors, Skin, Tissues, Photons, Numerical modeling, Scattering, Laser tissue interaction, Beam splitters, Optical properties

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Proceedings Article | 9 November 2005 Paper

Application of surface-enhanced Raman scattering (SERS) for the identification of anthraquinone dyes used in works of art

K. Chen, Marco Leona, K. C. Vo-Dinh, F. Yan, M. Wabuyele, Tuan Vo-Dinh

Proceedings Volume 5993, 59930M (2005) https://doi.org/10.1117/12.639103

KEYWORDS: Surface enhanced Raman spectroscopy, Silver, Nanoparticles, Raman spectroscopy, Glasses, Metals, Raman scattering, Microscopes, Luminescence, Molecules

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Proceedings Article | 8 November 2005 Paper

Portable AOTF Raman integrated tunable sensor (RAMiTS) for chemical and biosensing

K. Chen, M. Martin, Tuan Vo-Dinh

Proceedings Volume 5993, 599307 (2005) https://doi.org/10.1117/12.639098

KEYWORDS: Raman spectroscopy, Surface enhanced Raman spectroscopy, Sensors, Avalanche photodetectors, Biological weapons, Biosensing, Crystals, Chemical analysis, Raman scattering

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Proceedings Article | 23 May 2005 Paper

FRET based biosensor for detection of active NF-kB

Francesco Baldini, Lorenzo Citti, Claudio Domenici, Ambra Giannetti, Lorena Tedeschi, Tuan Vo-Dinh, Musundi Wabuyele

Proceedings Volume 5855, (2005) https://doi.org/10.1117/12.623696

KEYWORDS: Capillaries, Luminescence, Fluorescence resonance energy transfer, Proteins, Biosensors, Molecules, Signal detection, Glasses, Direct methods, Sensors

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Proceedings Article | 1 April 2005 Paper

Portable Raman device for detection of chemical and biological warfare agents

Musundi Wabuyele, Matthew Martin, Fei Yan, David Stokes, Joel Mobley, Brian Cullum, Alan Wintenberg, Roberto Lenarduzzi, Tuan Vo-Dinh

Proceedings Volume 5692, (2005) https://doi.org/10.1117/12.604451

KEYWORDS: Raman spectroscopy, Surface enhanced Raman spectroscopy, Biological weapons, Sensors, Biological detection systems, Avalanche photodetectors, Chemical analysis, Crystals, Linear filtering

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Proceedings Article | 1 April 2005 Paper

Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications

Matthew Martin, Musundi Wabuyele, Masoud Panjehpour, Mary Phan, Bergein Overholt, Robert DeNovo, Tamberlyn Moyers, Seong Gon Song, Tuan Vo-Dinh

Proceedings Volume 5692, (2005) https://doi.org/10.1117/12.604445

KEYWORDS: Luminescence, Tissues, Imaging systems, Hyperspectral imaging, Fluorescence spectroscopy, Cancer, Laser induced fluorescence, Spectroscopy, Reflectivity, Tunable filters

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Proceedings Article | 1 April 2005 Paper

Surface-enhanced Raman scattering molecular nanoprobes

Musundi Wabuyele, Fei Yan, Guy Griffin, Tuan Vo-Dinh

Proceedings Volume 5692, (2005) https://doi.org/10.1117/12.604447

KEYWORDS: Surface enhanced Raman spectroscopy, Silver, Raman spectroscopy, Nanoprobes, Nanoparticles, Raman scattering, Luminescence, Molecules, Chemical analysis, Multiplexing

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Proceedings Article | 1 April 2005 Paper

Hyperspectral fluorescence image analysis for use in medical diagnostics

Seong Kong, Zheng Du, Matthew Martin, Tuan Vo-Dinh

Proceedings Volume 5692, (2005) https://doi.org/10.1117/12.596463

KEYWORDS: Luminescence, Hyperspectral imaging, Tumors, Skin, Tissues, Imaging systems, Skin cancer, Diagnostics, Spatial filters, Image filtering

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Proceedings Article | 23 March 2005 Paper

Instrumentation considerations in spectral imaging for tissue demarcation: comparing three methods of spectral resolution

Steven Gebhart, David Stokes, Tuan Vo-Dinh, Anita Mahadevan-Jansen

Proceedings Volume 5694, (2005) https://doi.org/10.1117/12.611351

KEYWORDS: Imaging systems, Signal to noise ratio, Imaging spectroscopy, Tissues, Optical filters, Luminescence, Spectral resolution, Tissue optics, Auto-fluorescence imaging, Tunable filters

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Proceedings Article | 7 December 2004 Paper

Miniature biochip system for bioenvironmental applications

Musundi Wabuyele, Fei Yan, M. Martin, Guy Griffin, David Stokes, Dimitra Stratis-Cullum, Joel Mobley, Arpad Vass, Tuan Vo-Dinh

Proceedings Volume 5586, (2004) https://doi.org/10.1117/12.580126

KEYWORDS: Luminescence, Pathogens, Integrated circuits, CMOS sensors, Sensors, Liquids, Organisms, Optical filters, Statistical analysis, Medical diagnostics

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Proceedings Article | 7 December 2004 Paper

Portable Raman integrated tunable sensor (RAMiTs) for environmental field monitoring

Musundi Wabuyele, Matthew Martin, Fei Yan, David Stokes, Joel Mobley, Brian Cullum, Alan Wintenberg, Roberto Lenarduzzi, Tuan Vo-Dinh

Proceedings Volume 5586, (2004) https://doi.org/10.1117/12.580125

KEYWORDS: Raman spectroscopy, Surface enhanced Raman spectroscopy, Sensors, Avalanche photodetectors, Chemical analysis, Linear filtering, Crystals, Homeland security, Spectral resolution, Semiconductor lasers

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Proceedings Article | 1 July 2004 Paper

Surface-enhanced Raman scattering (SERS) detection for chemical and biological agents

Fei Yan, David Stokes, Musundi Wabuyele, Guy Griffin, Arpad Vass, Tuan Vo-Dinh

Proceedings Volume 5321, (2004) https://doi.org/10.1117/12.558478

KEYWORDS: Silver, Surface enhanced Raman spectroscopy, Oxides, Biological weapons, Raman spectroscopy, Biological detection systems, Ultraviolet radiation, Raman scattering, Glasses, Thin films

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Proceedings Article | 16 June 2004 Paper

Metallic nanostructures for plasmonic sensors using surface-enhanced fluorescence and Raman detection

Fei Yan, Musundi Wabuyele, Guy Griffin, Tuan Vo-Dinh

Proceedings Volume 5327, (2004) https://doi.org/10.1117/12.542455

KEYWORDS: Silver, Luminescence, Glasses, Raman spectroscopy, Surface enhanced Raman spectroscopy, Silicon, Plasmonic sensors, Rhodamine, Fluorescence spectroscopy, Molecules

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SPIE Journal Paper | 1 May 2004 Open Access

Screening for the breast cancer gene (BRCA1) using a biochip system and molecular beacon probes immobilized on solid surfaces

Mustafa Culha, David Stokes, Guy Griffin, Tuan Vo-Dinh

JBO, Vol. 9, Issue 03, (May 2004) https://doi.org/10.1117/12.10.1117/1.1691025

KEYWORDS: Luminescence, Solids, CMOS sensors, Breast cancer, CMOS technology, Sensors, Genetics, Ovarian cancer, Cancer, Glasses

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Proceedings Article | 22 July 2003 Paper

SERS gene probe for DNA diagnostics

David Stokes, Leonardo Allain, Narayana Isola, Tuan Vo-Dinh

Proceedings Volume 4958, (2003) https://doi.org/10.1117/12.488679

KEYWORDS: Surface enhanced Raman spectroscopy, Silver, Diagnostics, Raman spectroscopy, Molecules, Raman scattering, Glasses, Rhodamine, Sodium, Rhodamine B

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Proceedings Article | 22 July 2003 Paper

Laser-induced fluorescence for the detection of esophageal and skin cancer

Tuan Vo-Dinh, Masoud Panjehpour, Bergein Overholt, Clark Julius, Suzanne Overholt, Mary Phan

Proceedings Volume 4958, (2003) https://doi.org/10.1117/12.488678

KEYWORDS: Tissues, Laser induced fluorescence, Cancer, Skin, Skin cancer, Luminescence, Esophagus, Biopsy, Diagnostics, In vivo imaging

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Proceedings Article | 22 July 2003 Paper

Short-pulse laser propagation through tissues

Champak Das, Ashish Trivedi, Kunal Mitra, Tuan Vo-Dinh

Proceedings Volume 4958, (2003) https://doi.org/10.1117/12.497340

KEYWORDS: Tissues, Laser scattering, Scattering, Pulsed laser operation, Tissue optics, Absorption, Tumors, Laser beam propagation, Streak cameras, Photons

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Proceedings Article | 22 July 2003 Paper

Biochip using a biofluidic system for detection of E. coli and other pathogens

David Stokes, Leonardo Allain, Guy Griffin, Joel Mobley, Dimitra Stratis-Cullum, Alan Wintenberg, Robert Maples, Tuan Vo-Dinh

Proceedings Volume 4958, (2003) https://doi.org/10.1117/12.488677

KEYWORDS: Pathogens, Printing, Organisms, Photodiodes, Control systems, Sensors, Integrated circuits, Proteins, CMOS technology, Charge-coupled devices

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