Dr. Udo Klotzbach Profile

Dr. Udo Klotzbach

Managing Director at European Society of Thin Films e.V.

SPIE Involvement:

Track Chair | Editor | Author

Area of Expertise:

laser micro material processing , micro systems , micro fluidic

Websites:

Company Website

Profile Summary

Dr. techn. Dipl. Ing. Udo Klotzbach, gained his degree in “Electrical Engineering” at the Technical
University Dresden in 1995. Since July 1997 he has been employed at the Fraunhofer IWS Dresden.
He is experienced in laser micro materials processing and currently he is the Head of the Department for Micro Processing. With more than 10 years experience in managing RTD projects. Dr. Udo Klotzbach has experience in participation of several EC projects and he lead the European project LIFT project (Large scale integrating project NMP 2-LA-2009- 228587) with 21 partners and 16 Mio. Euro Budget.

Publications (23)

Proceedings Article | 5 March 2021 Presentation

Presentation

Detection and analysis of airborne acoustic signals in direct laser interference patterning

Tobias Steege, Sabri Alamri, Udo Klotzbach, Andrés Lasagni, Tim Kunze

Proceedings Volume 11674, 1167405 (2021) https://doi.org/10.1117/12.2587162

KEYWORDS: Acoustics, Signal detection, Optical lithography, Airborne laser technology, Pulsed laser operation, Laser processing, Laser energy, Beam shaping, Acoustic emission

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Proceedings Article | 2 March 2020 Presentation + Paper

Presentation + Paper

Laser-induced cell injury in closed micro physiological systems: a novel method to study regeneration processes in vitro

Udo Klotzbach, Florian Schmieder, Deborah Förster, Mechthild Rösler, Jan Sradnick, Bernd Hohenstein, Frank Sonntag

Proceedings Volume 11268, 1126804 (2020) https://doi.org/10.1117/12.2566162

KEYWORDS: Injuries, In vitro testing, Systems modeling, Microfluidics, Laser systems engineering, Laser irradiation, Laser ablation, Lab on a chip

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Proceedings Article | 2 March 2020 Paper

Paper

Efficiency improvement of multilayer lab-on-a-chip production by dynamic beam shaping

Stephan Behrens, Frank Sonntag, Thomas Kuntze, Volker Franke, Patrick Schöps, Florian Schmieder, Udo Klotzbach

Proceedings Volume 11268, 112681C (2020) https://doi.org/10.1117/12.2542018

KEYWORDS: Mirrors, Scanners, Lab on a chip, Beam shaping, Control systems, Logic, Polymers, Interfaces, System on a chip, Laser processing

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Proceedings Article | 4 March 2019 Presentation + Paper

Presentation + Paper

Functionalization of fiber-reinforced plastic based on laser micro structuring

Andrés Fabían Lasagni, Jana Gebauer, Udo Klotzbach

Proceedings Volume 10906, 109060C (2019) https://doi.org/10.1117/12.2505114

KEYWORDS: Coating, Composites, Fiber lasers, Fiber reinforced polymers, Metals, Laser processing, Interfaces

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Proceedings Article | 4 March 2019 Presentation + Paper

Presentation + Paper

Quo Vadis surface functionalization: How direct laser interference patterning tackle productivity and flexibility in industrial applications

S. Alamri, A. Aguilar-Morales, T. Steege, B. Krupop, A. Lasagni, B. Voisiat, V. Lang, S. Storm, F. Schell, C. Zwahr, M. Bieda, U. Klotzbach, C. Kracht, T. Kunze

Proceedings Volume 10906, 109060S (2019) https://doi.org/10.1117/12.2514209

KEYWORDS: Laser applications, Optical lithography, Laser processing, Pulsed laser operation, Picosecond phenomena, Biomimetics, High power lasers, Natural surfaces, Control systems, Laser sources

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Proceedings Article | 14 March 2018 Presentation

Presentation

R2R suitable processing of large area organic electronics with integrated barrier layer using short-pulsed lasers

Udo Klotzbach, Henri Fledderus, Niels Friedrich-Schilling, Thomas Kuntze

Proceedings Volume 10520, 105200U (2018) https://doi.org/10.1117/12.2319072

Proceedings Article | 7 March 2017 Presentation + Paper

Presentation + Paper

Roll-to-roll suitable short-pulsed laser scribing of organic photovoltaics and close-to-process characterization

Philipp Wollmann, Thomas Kuntze, Henri Fledderus, Udo Klotzbach

Proceedings Volume 10092, 100920J (2017) https://doi.org/10.1117/12.2255934

KEYWORDS: Organic photovoltaics, Pulsed laser operation, Picosecond phenomena, Laser systems engineering, Electrodes, Laser processing, Calcium, Laser ablation, Hyperspectral imaging, Solar cells

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Proceedings Article | 28 February 2017 Presentation + Paper

Presentation + Paper

Microfluidic system for in-vitro hypoxia assays

C. Steinfelder, M. Busek, S. Grünzner, T. Steege, F. Schmieder, U. Klotzbach, F. Sonntag

Proceedings Volume 10061, 1006110 (2017) https://doi.org/10.1117/12.2253664

KEYWORDS: Hypoxia, Oxygen, Microfluidics, 3D modeling, Animal model studies, Systems modeling, In vitro testing, Lab on a chip, Mode conditioning cables, Animal testing, Nitrogen, Luminescence, Velocity measurements, Tissues, Gases

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Proceedings Article | 28 February 2017 Presentation + Paper

Presentation + Paper

Lab-on-a-chip platform for high throughput drug discovery with DNA-encoded chemical libraries

M. Cui, S. Grünzner, F. Reddavide, M. Busek, U. Klotzbach, F. Sonntag, Y. Zhang, C. Steinfelder

Proceedings Volume 10061, 1006111 (2017) https://doi.org/10.1117/12.2253840

KEYWORDS: Industrial chemicals, Molecules, Signal processing, Chemistry, Biological research, Chemical analysis, Proteins, Solids, Thermodynamics, Signal to noise ratio

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The fast development of DNA-encoded chemical libraries (DECL) in the past 10 years has received great attention from pharmaceutical industries. It applies the selection approach for small molecular drug discovery. Because of the limited choices of DNA-compatible chemical reactions, most DNA-encoded chemical libraries have a narrow structural diversity and low synthetic yield. There is also a poor correlation between the ranking of compounds resulted from analyzing the sequencing data and the affinity measured through biochemical assays. By combining DECL with dynamical chemical library, the resulting DNA-encoded dynamic library (EDCCL) explores the thermodynamic equilibrium of reversible reactions as well as the advantages of DNA encoded compounds for manipulation/detection, thus leads to enhanced signal-to-noise ratio of the selection process and higher library quality. However, the library dynamics are caused by the weak interactions between the DNA strands, which also result in relatively low affinity of the bidentate interaction, as compared to a stable DNA duplex. To take advantage of both stably assembled dual-pharmacophore libraries and EDCCLs, we extended the concept of EDCCLs to heat-induced EDCCLs (hi-EDCCLs), in which the heat-induced recombination process of stable DNA duplexes and affinity capture are carried out separately. To replace the extremely laborious and repetitive manual process, a fully automated device will facilitate the use of DECL in drug discovery. Herein we describe a novel lab-on-a-chip platform for high throughput drug discovery with hi-EDCCL. A microfluidic system with integrated actuation was designed which is able to provide a continuous sample circulation by reducing the volume to a minimum. It consists of a cooled and a heated chamber for constant circulation. The system is capable to generate stable temperatures above 75 °C in the heated chamber to melt the double strands of the DNA and less than 15 °C in the cooled chamber, to reanneal the reshuffled library. In the binding chamber (the cooled chamber) specific retaining structures are integrated. These hold back beads functionalized with the target protein, while the chamber is continuously flushed with library molecules. Afterwards the whole system can be flushed with buffer to wash out unspecific bound molecules. Finally the protein-loaded beads with attached molecules can be eluted for further investigation.

Proceedings Article | 17 February 2017 Paper

Paper

Patterning of organic photovoltaic on R2R processed thin film barriers using IR laser sources

U. Klotzbach, H. Fledderus, H. Akkerman, N. Friedrich Schilling, A. Salem

Proceedings Volume 10092, 100920I (2017) https://doi.org/10.1117/12.2248533

KEYWORDS: Laser development, Thin films, Calcium, Laser ablation, Pulsed laser operation, Picosecond phenomena, Laser systems engineering, Femtosecond phenomena, Laser induced damage, Optical lithography

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Proceedings Article | 21 March 2016 Presentation + Paper

Presentation + Paper

Universal lab-on-a-chip platform for complex, perfused 3D cell cultures

F. Sonntag, F. Schmieder, J. Ströbel, S. Grünzner, M. Busek, U. Klotzbach, K. Günther, T. Steege, C. Polk

Proceedings Volume 9705, 970516 (2016) https://doi.org/10.1117/12.2218606

KEYWORDS: Lab on a chip, Microfluidics, 3D printing, BioMEMS, Nonimpact printing, Tissue engineering, Rapid manufacturing, Medical diagnostics, Skin, Liver, Oxygen, Tissues, Manufacturing, Printing, Sensors, Laser applications, Embedded systems

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Proceedings Article | 12 March 2015 Paper

Paper

Laser processing of glass fiber reinforced thermoplastics with different wavelengths and pulse durations

N. Schilling, U. Klotzbach, B. Krupop

Proceedings Volume 9351, 93510N (2015) https://doi.org/10.1117/12.2081903

KEYWORDS: Laser ablation, Glasses, Polymers, Laser processing, Carbon, Fiber lasers, Carbon dioxide lasers, Picosecond phenomena, Laser systems engineering, Absorption

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Proceedings Article | 12 March 2015 Paper

Paper

Multilayer based lab-on-a-chip-systems for substance testing

Frank Sonntag, Udo Klotzbach, Volker Franke, Florian Schmieder, Stefan Grünzner, Mathias Busek

Proceedings Volume 9351, 93510C (2015) https://doi.org/10.1117/12.2083100

KEYWORDS: Microfluidics, Lab on a chip, Multilayers, Manufacturing, Laser bonding, Polymers, Laser applications, Laser development, Diffusion, Laser tissue interaction

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Proceedings Article | 12 March 2014 Paper

Paper

Effective mitigation of photodarkening in Yb-doped lasers based on Al-silicate using UV/visible light

Udo Klotzbach, Stefano Taccheo, Riccardo Piccoli, Thierry Robin, David Méchin, Thomas Brand

Proceedings Volume 8961, 896121 (2014) https://doi.org/10.1117/12.2039013

KEYWORDS: Fiber lasers, Absorption, Photons, Visible radiation, Doping, Ions, Laser applications, Ytterbium, Laser resonators, Fiber Bragg gratings

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Proceedings Article | 16 February 2012 Paper

Paper

Formation of tribological structures by laser ablation

Sami Hendow, Udo Klotzbach, Mike Paschke, Niels Schilling

Proceedings Volume 8243, 82430X (2012) https://doi.org/10.1117/12.908940

KEYWORDS: Pulsed laser operation, Laser ablation, Solids, Abrasives, Semiconductor lasers, Fiber lasers, Particles, Laser processing, Diffusion, Reflection

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Proceedings Article | 26 May 2009 Paper

Paper

Novel lab-on-a-chip system for the label-free detection of DNA hybridization and protein-protein interaction by surface plasmon resonance (SPR)

N. Schilling, E. Beyer, M. Mertig, F. Sonntag, U. Klotzbach, N. Danz, S. Schmieder

Proceedings Volume 7365, 73650Q (2009) https://doi.org/10.1117/12.821467

KEYWORDS: Proteins, Gold, Microfluidics, Printing, Sensors, Surface plasmons, Lab on a chip, Molecules, Diagnostics, Integrated optics

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Proceedings Article | 26 May 2009 Paper

Paper

Characterization of novel micro fluidic approaches for increased sensitivity of sensors measuring surface reactions

U. Klotzbach, F. Sonntag, M. Gruchow, S. Vogelsang, F. Mehringer, E. Beyer

Proceedings Volume 7365, 73650P (2009) https://doi.org/10.1117/12.821463

KEYWORDS: Dielectrophoresis, Particles, Electrodes, Diffusion, Dielectrics, Sensors, Statistical analysis, Lab on a chip, Molecules, Systems modeling

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Proceedings Article | 20 March 2007 Paper

Paper

Requirements and potentialities of packaging for bioreactors with LTCC and polymers

Udo Klotzbach, Lothar Morgenthal, Volker Franke, Eckhard Beyer, Frank Sonntag

Proceedings Volume 6459, 645902 (2007) https://doi.org/10.1117/12.702206

KEYWORDS: Polymers, Ceramics, Sensors, Polymeric sensors, Pulsed laser operation, Nd:YAG lasers, Laser applications, Laser systems engineering, Lab on a chip, Packaging

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Proceedings Article | 20 March 2007 Paper

Paper

Potentials of fiber laser technology in microfabrication

Roger Püschel, Udo Klotzbach, Michael Panzner, Volker Franke

Proceedings Volume 6459, 64590J (2007) https://doi.org/10.1117/12.700486

KEYWORDS: Fiber lasers, Laser cutting, Laser systems engineering, Rod lasers, Laser applications, Laser marking, Laser drilling, Ruby, Aluminum, Laser ablation

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Proceedings Article | 15 July 2004 Paper

Paper

Excimer lasers turning flexible: variable marking with micromirror devices

Thomas Kuntze, Udo Klotzbach, Eckhard Beyer

Proceedings Volume 5339, (2004) https://doi.org/10.1117/12.532134

KEYWORDS: Laser marking, Excimer lasers, Micromirrors, Mirrors, Photomasks, Reflectivity, Pulsed laser operation, Ultraviolet radiation, Titanium, Oxides

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Proceedings Article | 15 July 2004 Paper

Paper

Influence of gas on cutting silicon with solid state laser

F. Sonntag, Thomas Kuntze, Eckhard Beyer, Michael Panzner, Stephanie Maelzer, Udo Klotzbach, Michael Doetschel

Proceedings Volume 5339, (2004) https://doi.org/10.1117/12.532133

KEYWORDS: Silicon, Laser cutting, Helium, Argon, Semiconductor lasers, Semiconducting wafers, Gases, Oxygen, Solid state lasers, Laser processing

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Proceedings Article | 18 November 2003 Paper

Paper

New excimer laser marking method using MMD

Udo Klotzbach, Thomas Kuntze, Michael Panzner, Eckhard Beyer

Proceedings Volume 5063, (2003) https://doi.org/10.1117/12.541162

KEYWORDS: Laser marking, Excimer lasers, Photomasks, Pulsed laser operation, Mirrors, Reflectivity, Micromirrors, Coating, Packaging, Phase shifts

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Proceedings Article | 18 June 2002 Paper

Paper

Processing of silicon by Nd:YAG lasers with harmonics generation

Udo Klotzbach, Jorg Kasper, Hendrik Wust, Eckhard Beyer, Michael Panzner

Proceedings Volume 4637, (2002) https://doi.org/10.1117/12.470659

KEYWORDS: Silicon, Semiconductor lasers, Ultraviolet radiation, Plasma, Semiconducting wafers, Harmonic generation, Laser cutting, Laser ablation, Absorption, Etching

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Showing 5 of 23 publications

Proceedings Volume Editor (9)

SPIE Conference Volume | 27 April 2021

Laser-based Micro- and Nanoprocessing XV

SPIE Conference Volume | 15 April 2020

Laser-based Micro- and Nanoprocessing XIV

SPIE Conference Volume | 7 June 2019

Laser-based Micro- and Nanoprocessing XIII

SPIE Conference Volume | 6 June 2018

Laser-based Micro- and Nanoprocessing XII

SPIE Conference Volume | 21 March 2017

Laser-based Micro- and Nanoprocessing XI

Showing 5 of 9 publications

Conference Committee Involvement (18)

Laser-based Micro- and Nanoprocessing XVI

25 January 2022 | San Francisco, California, United States

Laser-based Micro- and Nanoprocessing XV

6 March 2021 | Online Only, California, United States

Fiber Lasers and Glass Photonics: Materials through Applications II

6 April 2020 | Online Only, France

Laser-based Micro- and Nanoprocessing XIV

3 February 2020 | San Francisco, California, United States

Laser-based Micro- and Nanoprocessing XIII

5 February 2019 | San Francisco, California, United States

Fiber Lasers and Glass Photonics: Materials through Applications

22 April 2018 | Strasbourg, France

Laser-based Micro- and Nanoprocessing XII

30 January 2018 | San Francisco, California, United States

Laser-based Micro- and Nanoprocessing XI

31 January 2017 | San Francisco, California, United States

Laser-based Micro- and Nanoprocessing X

16 February 2016 | San Francisco, California, United States

Laser-based Micro- and Nanoprocessing IX

10 February 2015 | San Francisco, California, United States

Laser-based Micro- and Nano-Processing VIII

5 February 2014 | San Francisco, California, United States

Laser-based Micro- and Nanopackaging and Assembly VII

5 February 2013 | San Francisco, California, United States

Laser-based Micro- and Nanopackaging and Assembly VI

25 January 2012 | San Francisco, California, United States

Laser-based Micro- and Nanopackaging and Assembly V

26 January 2011 | San Francisco, California, United States

Laser-based Micro- and Nanopackaging and Assembly IV

27 January 2010 | San Francisco, California, United States

Laser-based Micro- and Nanopackaging and Assembly III

28 January 2009 | San Jose, California, United States

Laser-Based Micro- and Nano-Packaging and Assembly II

22 January 2008 | San Jose, California, United States

Workshop on Laser Applications in Europe

23 November 2005 | Dresden, Germany

Showing 5 of 18 Conference Committees

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