Low temperature co-fired ceramic (LTCC) technology was originally developed for the realization of multilayer circuits
of high reliability. It was recognized that LTCC technology is a valuable development in thick film technology, which
launches new application areas as it becomes evident that complex three-dimensional structures can easily be realized.
When considered for biological applications ceramic tape material must be proved with regard to its biocompatibility. A
selection of appropriate commercially available ceramic tapes has been characterized in respect to the influence on
proliferation, viability and adherence of cells. Aspects of realization of a complex biological monitoring module
comprising a three-dimensional network of channels and cavities will be demonstrated.
This paper presents a new concept for bonding micro-parts with dimensions in the range of 50 μm to 300 μm. Two different kinds of adhesives - polyurethane adhesive foil and hot melt glue - were applied to a basic substrate by different techniques. The focused and concentrated hot gas stream softened glue which had been applied in a solid state. Micro-parts were then embossed in the softened glue, or covered and shielded by it. In this way, a rigid and compact bond was obtained after cooling. For the positioning of micro-parts (optical fibers), it has been necessary to manufacture adequate V-grooves. Finite element analyses using the ANSYS<sup>TM</sup> program package were performed in order to evaluate parameters which govern the heat transfer to the adhesive and substrate respectively. Experimental results are in good agreement with results obtained by the numerical simulations. The advantages of this new approach are small system size, low capital costs, simple usage, applicability to many material combinations, easy integration into existing production lines, etc.