Prof. Xiaoliang Sunney Xie Profile

Prof. Xiaoliang Sunney Xie

Director at Peking Univ

SPIE Involvement:

Conference Program Committee | Author | Editor

Publications (26)

Proceedings Article | 5 March 2021 Presentation

Super-resolution imaging reveals spatio-temporal propagation of human replication foci mediated by CTCF-organized chromatin structures

Ziqing Winston Zhao, Qian Peter Su, Sunney Xie, Yujie Sun

Proceedings Volume 11650, 1165004 (2021) https://doi.org/10.1117/12.2582893

KEYWORDS: Super resolution, Electromagnetic coupling, Visualization, Stochastic processes, Optical microscopy, Microscopy, Biological research, Bioinformatics

Proceedings Article | 20 November 2019 Paper

Label-free imaging of lymph nodes with stimulated Raman scattering microscopy

Yuanzhen Suo, Wenlong Yang, Fake Lu, Xiaoliang Sunney Xie

Proceedings Volume 11190, 111900J (2019) https://doi.org/10.1117/12.2536264

KEYWORDS: Lymphatic system, Raman scattering

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Proceedings Article | 24 April 2017 Presentation

Label-free biomolecular characterization of human breast cancer tissue with stimulated Raman scattering (SRS) spectral imaging (Conference Presentation)

Fa-Ke Lu, David Calligaris, Yuanzhen Suo, Sandro Santagata, Alexandra Golby, X. Sunney Xie, Melissa Mallory, Mehra Golshan, Deborah Dillon, Nathalie Y. Agar

Proceedings Volume 10069, 100690R (2017) https://doi.org/10.1117/12.2253366

KEYWORDS: Tumors, Breast cancer, Tissues, Microscopy, Raman scattering, Cancer, Raman spectroscopy, Proteins, Calcium, Imaging spectroscopy

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Proceedings Article | 27 April 2016 Open Access

Coherent Raman scattering microscopy: an emerging platform for biology and medicine (Conference Presentation)

Sunney Xie

Proceedings Volume 9712, 971206 (2016) https://doi.org/10.1117/12.2219754

KEYWORDS: Microscopy, Raman scattering, Biomedical optics, Biology, Medicine, Multiphoton microscopy, Raman spectroscopy, Imaging spectroscopy, Spectroscopy, Tissues

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SPIE Journal Paper | 23 May 2014 Open Access

Three-dimensional chemical imaging of skin using stimulated Raman scattering microscopy

Dane Drutis, Thomas Hancewicz, Eugene Pashkovski, Lin Feng, Dawn Mihalov, Gary Holtom, Kavssery Ananthapadmanabhan, X. Sunney Xie, Manoj Misra

JBO, Vol. 19, Issue 11, 111604, (May 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.11.111604

KEYWORDS: Skin, Proteins, 3D image processing, Imaging spectroscopy, Raman spectroscopy, Raman scattering, Microscopy, Visualization, Spectroscopy, Tissues

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Proceedings Article | 28 February 2014 Paper

High-performance fiber parametric oscillator for coherent Raman microscopy

Erin Lamb, Simon Lefrancois, Minbiao Ji, William Wadsworth, X. Sunney Xie, Frank Wise

Proceedings Volume 8948, 894815 (2014) https://doi.org/10.1117/12.2037328

KEYWORDS: Optical parametric oscillators, Microscopy, Picosecond phenomena, Oscillators, Optical filters, Raman spectroscopy, Dispersion, Fiber lasers, CARS tomography, Solid state physics

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Proceedings Article | 9 February 2012 Paper

Towards a tunable fiber source for coherent Raman imaging

Simon Lefrancois, Dan Fu, Gary Holtom, Lingjie Kong, William Wadsworth, Patrick Schneider, Robert Herda, Armin Zach, X. Sunney Xie, Frank Wise

Proceedings Volume 8226, 822620 (2012) https://doi.org/10.1117/12.920187

KEYWORDS: Chromium, Picosecond phenomena, Fiber lasers, Microscopy, Dispersion, Coherence imaging, Raman spectroscopy, Four wave mixing, Fiber amplifiers, Tissues

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Proceedings Article | 11 February 2011 Paper

All fiber 1064-nm time-lens source for coherent anti-Stokes Raman scattering and stimulated Raman scattering microscopy

Ke Wang, Christian Freudiger, Jennifer Lee, Brian Saar, X. Sunney Xie, Chris Xu

Proceedings Volume 7903, 79030X (2011) https://doi.org/10.1117/12.875898

KEYWORDS: Mode locking, Chromium, Picosecond phenomena, Fiber lasers, Microscopy, CARS tomography, Modulation, Modulators, Fiber amplifiers, Raman scattering

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SPIE Journal Paper | 1 February 2011 Open Access

Multimodal coherent anti-Stokes Raman scattering microscopy reveals microglia-associated myelin and axonal dysfunction in multiple sclerosis-like lesions in mice

Jaime Imitola, Stine Rasmussen, Yingru Liu, Tanuja Chitnis, Samia Khoury, Daniel Côté, X. Sunney Xie, Charles Lin, Richard Sidman

JBO, Vol. 16, Issue 02, 021109, (February 2011) https://doi.org/10.1117/12.10.1117/1.3533312

KEYWORDS: Reflectivity, Axons, CARS tomography, Spinal cord, Tissues, Microscopy, Visualization, Confocal microscopy, Green fluorescent protein, Microscopes

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SPIE Journal Paper | 1 February 2011 Open Access

Special Section Guest Editorial: Coherent Raman Imaging Techniques and Biomedical Applications

Eric Potma, Ji-Xin Cheng, X. Sunney Xie

JBO, Vol. 16, Issue 02, 021101, (February 2011) https://doi.org/10.1117/12.10.1117/1.3558735

KEYWORDS: Raman spectroscopy, Biomedical optics, Chromium, Coherence imaging, Tissues, Microscopes, Cameras, Photography, Biology, Microscopy

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SPIE Journal Paper | 1 February 2011 Open Access

Label-free imaging of biomolecules in food products using stimulated Raman microscopy

Maarten Roeffaers, Xu Zhang, Christian Freudiger, Brian Saar, X. Sunney Xie, Marjolein van Ruijven, Gerard van Dalen, Chunhong Xiao

JBO, Vol. 16, Issue 02, 021118, (February 2011) https://doi.org/10.1117/12.10.1117/1.3516591

KEYWORDS: Raman spectroscopy, Microscopy, Proteins, Raman scattering, Luminescence, Optical parametric oscillators, Molecular spectroscopy, Coherence imaging, Signal detection, Modulation

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Proceedings Article | 26 February 2010 Paper

Short-pulse fiber lasers for Raman microscopies

F. Wise, W. Renninger, S. Lefrancois, K. Kieu, M. Farrar, C, Schaffer, Brian Saar, Gary Holtom, Sunney Xie

Proceedings Volume 7569, 75690I (2010) https://doi.org/10.1117/12.841406

KEYWORDS: Microscopy, Fiber lasers, Picosecond phenomena, Dispersion, Raman spectroscopy, Solitons, Femtosecond phenomena, Amplifiers, Optical parametric oscillators, Pulsed laser operation

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Proceedings Article | 25 February 2009 Paper

Fiber lasers for CARS microscopy

F. Wise, K. Kieu, Brian Saar, Gary Holtom, Sunney Xie

Proceedings Volume 7183, 718318 (2009) https://doi.org/10.1117/12.817128

KEYWORDS: Microscopy, Picosecond phenomena, Fiber lasers, Optical parametric oscillators, Fiber amplifiers, Oscillators, CARS tomography, Amplifiers, Laser systems engineering, Raman spectroscopy

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Proceedings Article | 13 February 2009 Paper

Stimulated Raman scattering microscopy for biomedical imaging

Wei Min, Christian Freudiger, Sijia Lu, Chengwei He, Jing Kang, X. Sunney Xie

Proceedings Volume 7183, 718320 (2009) https://doi.org/10.1117/12.809802

KEYWORDS: Raman spectroscopy, Microscopy, Raman scattering, Biomedical optics, Tissues, Multiphoton microscopy, Brain, Modulation, Neuroimaging, Skin

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Proceedings Article | 15 February 2008 Paper

Adaptive optics applied to coherent anti-Stokes Raman scattering microscopy

John Girkin, Simon Poland, Amanda Wright, Christian Freudiger, Conor Evans, X. Sunney Xie

Proceedings Volume 6860, 68600T (2008) https://doi.org/10.1117/12.764445

KEYWORDS: Adaptive optics, Microscopy, Aberration correction, Microscopes, Tissue optics, Actuators, Mirrors, Genetic algorithms, CARS tomography, Image enhancement

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Proceedings Article | 12 July 2007 Paper

A new easy to use light source for CARS microscopy based on an optical parametric oscillator

Ingo Rimke, Conor Evans, Edlef Büttner, Sunny Xie

Proceedings Volume 6630, 66300R (2007) https://doi.org/10.1117/12.728126

KEYWORDS: Optical parametric oscillators, Microscopy, Picosecond phenomena, Light sources, Mirrors, Imaging systems, CARS tomography, Tissues, Nonlinear optics, Laser sources

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Proceedings Article | 10 February 2007 Paper

CARS imaging with a new 532-nm synchronously pumped picosecond OPO

Edlef Büttner, Silvia Carrasco, Conor Evans, Feruz Ganikhanov, Johannes Herbst, Daniel Kopf, Ingo Rimke, Sunney Xie

Proceedings Volume 6442, 64420C (2007) https://doi.org/10.1117/12.700072

KEYWORDS: Optical parametric oscillators, Picosecond phenomena, Microscopy, CARS tomography, Mirrors, Multiphoton microscopy, Laser sources, Raman spectroscopy, Light sources, Imaging systems

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Proceedings Article | 1 October 2005 Paper

Towards an integrated coherent anti-Stokes Raman scattering (CARS) microscopy system

Francois Legare, Feruz Ganikhanov, X. Sunney Xie

Proceedings Volume 5971, 597108 (2005) https://doi.org/10.1117/12.629926

KEYWORDS: Microscopes, Microscopy, Raman spectroscopy, CARS tomography, Signal detection, Imaging systems, Optical parametric oscillators, Picosecond phenomena, Raman scattering, Signal processing

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Proceedings Article | 23 May 2005 Paper

Observation of a power law memory kernel for distance fluctuation within a single protein molecule

Wei Min, Guobin Luo, Binny Cherayil, Samuel Kou, X. Sunney Xie

Proceedings Volume 5841, (2005) https://doi.org/10.1117/12.608514

KEYWORDS: Proteins, Molecules, Luminescence, Correlation function, Crystals, Chemistry, Photons, Particles, Biology, Fluctuations and noise

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Proceedings Article | 17 June 2002 Paper

Recent advances on Coherent Anti-Strokes Raman scattering (CARS) microscopy

Ji-xin Cheng, Eric Potma, Sunney Xie

Proceedings Volume 4620, (2002) https://doi.org/10.1117/12.470697

KEYWORDS: Microscopy, Cell death, CARS tomography, Microscopes, Raman spectroscopy, Proteins, Diffusion, Luminescence, Confocal microscopy, Infrared imaging

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Proceedings Article | 24 April 1998 Paper

Optical microscopy and spectroscopy beyond the diffraction limit

Lukas Novotny, Erik Sanchez, Sunney Xie

Proceedings Volume 3273, (1998) https://doi.org/10.1117/12.306128

KEYWORDS: Metals, Near field, Optical microscopy, Near field optics, Aluminum, Spectroscopy, Diffraction, Luminescence, Dielectrics, Dielectric polarization

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Proceedings Article | 7 April 1995 Paper

Near-field single molecule spectroscopy

Sunney Xie, Robert Dunn

Proceedings Volume 2385, (1995) https://doi.org/10.1117/12.206436

KEYWORDS: Molecules, Near field, Luminescence, Spectroscopy, Molecular spectroscopy, Single molecule spectroscopy, Glasses, Fluorescence spectroscopy, Spatial resolution, Aluminum

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Proceedings Article | 17 August 1994 Paper

Near-field fluorescence microscopy and spectroscopy: applications to single chromophores, single proteins, and photosynthetic membranes

Sunney Xie, Errol Allen, Gary Holtom, Robert Dunn, Laurens Mets

Proceedings Volume 2137, (1994) https://doi.org/10.1117/12.182708

KEYWORDS: Luminescence, Near field, Molecules, Proteins, Spatial resolution, Spectroscopy, Chromophores, Picosecond phenomena, Microscopes, Near field optics

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Proceedings Article | 1 April 1992 Paper

Femtosecond fluorescence depolarization study of photosynthetic antenna proteins: observation of ultrafast energy transfer in trimeric C-phycocyanin and allophycocyanin

Sunney Xie, Mei Du, Laurens Mets, Graham Fleming

Proceedings Volume 1640, (1992) https://doi.org/10.1117/12.58278

KEYWORDS: Luminescence, Compound parabolic concentrators, Energy transfer, Absorption, Crystals, Chromophores, Laser spectroscopy, Biochemistry, Picosecond phenomena, Femtosecond phenomena

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Proceedings Article | 1 June 1991 Paper

Picosecond absorption and circular dichroism studies of proteins

John Simon, Sunney Xie, Robert Dunn

Proceedings Volume 1432, (1991) https://doi.org/10.1117/12.44220

KEYWORDS: Picosecond phenomena, Absorption, Adaptive optics, Proteins, Dichroic materials, Spectroscopy, Excitons, Rubidium, Circular dichroism spectroscopy, Electroactive polymers

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Proceedings Article | 1 May 1990 Paper

Picosecond circular dichroism spectroscopy: experiment, theory, and applications to protein dynamics

Sunney Xie, John Simon

Proceedings Volume 1204, (1990) https://doi.org/10.1117/12.17688

KEYWORDS: Dichroic materials, Signal detection, Circular dichroism spectroscopy, Proteins, Picosecond phenomena, Modulation, Polarization, Birefringence, Laser beam diagnostics, Biochemistry

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Showing 5 of 26 publications

Proceedings Volume Editor (2)

SPIE Conference Volume | 11 April 2018

Multiphoton Microscopy in the Biomedical Sciences XVIII

SPIE Conference Volume | 17 May 2017

Multiphoton Microscopy in the Biomedical Sciences XVII

Conference Committee Involvement (29)

Advanced Chemical Microscopy for Life Science and Translational Medicine 2025

25 January 2025 | San Francisco, California, United States

Advanced Chemical Microscopy for Life Science and Translational Medicine 2024

27 January 2024 | San Francisco, California, United States

Advanced Chemical Microscopy for Life Science and Translational Medicine 2023

28 January 2023 | San Francisco, California, United States

Multiphoton Microscopy in the Biomedical Sciences XXII

23 January 2022 | San Francisco, California, United States

Advanced Chemical Microscopy for Life Science and Translational Medicine 2022

23 January 2022 | San Francisco, California, United States

Advanced Chemical Microscopy for Life Science and Translational Medicine 2021

6 March 2021 | Online Only, California, United States

Multiphoton Microscopy in the Biomedical Sciences XXI

6 March 2021 | Online Only, California, United States

Multiphoton Microscopy in the Biomedical Sciences XX

2 February 2020 | San Francisco, California, United States

Advanced Chemical Microscopy for Life Science and Translational Medicine

1 February 2020 | San Francisco, California, United States

Multiphoton Microscopy in the Biomedical Sciences XIX

3 February 2019 | San Francisco, California, United States

Multiphoton Microscopy in the Biomedical Sciences XVIII

28 January 2018 | San Francisco, California, United States

Multiphoton Microscopy in the Biomedical Sciences XVII

29 January 2017 | San Francisco, California, United States

Multiphoton Microscopy in the Biomedical Sciences XVI

14 February 2016 | San Francisco, California, United States

Multiphoton Microscopy in the Biomedical Sciences XV

8 February 2015 | San Francisco, California, United States

Multiphoton Microscopy in the Biomedical Sciences XIV

2 February 2014 | San Francisco, California, United States

Multiphoton Microscopy in the Biomedical Sciences XIII

3 February 2013 | San Francisco, California, United States

Multiphoton Microscopy in the Biomedical Sciences XII

22 January 2012 | San Francisco, California, United States

Multiphoton Microscopy in the Biomedical Sciences XI

23 January 2011 | San Francisco, California, United States

Multiphoton Microscopy in the Biomedical Sciences X

24 January 2010 | San Francisco, California, United States

Multiphoton Microscopy in the Biomedical Sciences IX

25 January 2009 | San Jose, California, United States

Multiphoton Microscopy in the Biomedical Sciences VIII

20 January 2008 | San Jose, California, United States

Confocal, Multiphoton, and Nonlinear Microscopic Imaging

17 June 2007 | Munich, Germany

Multiphoton Microscopy in the Biomedical Sciences VII

21 January 2007 | San Jose, California, United States

Multiphoton Microscopy in the Biomedical Sciences VI

22 January 2006 | San Jose, California, United States

Multiphoton Microscopy in the Biomedical Sciences V

23 January 2005 | San Jose, CA, United States

Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems II

26 May 2004 | Maspalomas, Gran Canaria Island, Spain

Multiphoton Microscopy in the Biomedical Sciences IV

25 January 2004 | San Jose, CA, United States

Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems

2 June 2003 | Santa Fe, New Mexico, United States

Multiphoton Microscopy in the Biomedical Sciences III

26 January 2003 | San Jose, CA, United States

Showing 5 of 29 Conference Committees

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